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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12171 scientific papers returned from the database with the search filters currently being used below.
There are 12171 scientific papers returned from the database with the search filters currently being used below.
BMP signaling is required for amphioxus tail regeneration
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Citation:
Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print] Epub:
Yes Abstract:
Amphioxus, a cephalochordate, is an ideal animal in which to address questions about the evolution of regenerative ability and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Branchiostoma japonicum (amphioxus) Citation Extract: Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S. BMP signaling is required for amphioxus tail regeneration. Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print]. |
BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish
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Citation:
PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996 Epub:
Not Epub Abstract:
Pharyngeal pouches, a series of outpocketings that bud from the foregut endoderm, are essential to the formation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q. BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996. |
Piezo1 is required for outflow tract and aortic valve development
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Citation:
J Mol Cell Cardiol. 2020 Jun;143:51-62. doi: 10.1016/j.yjmcc.2020.03.013. Epub 2020 Apr 3. PMID: 32251670 Epub:
Not Epub Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faucherre A, Moha Ou Maati H, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 is required for outflow tract and aortic valve development. J Mol Cell Cardiol. 2020 Jun;143:51-62. doi: 10.1016/j.yjmcc.2020.03.013. Epub 2020 Apr 3. PMID: 32251670. |
CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses
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Citation:
Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071 Epub:
Not Epub Abstract:
Infection by rapidly growing Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF), a genetic disease... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L. CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses. Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071. |
Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate
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Citation:
Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w Epub:
Not Epub Abstract:
Tissue internalisation is a key morphogenetic mechanism by which embryonic tissues generate complex internal organs and a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW. Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w. |
Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort
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Citation:
J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x Epub:
Yes Abstract:
Congenital heart defects (CHDs), the most common congenital human birth anomalies, involves complex genetic factors. Wnt/β-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu M-J, Ma X-Y, Ding P-C, Tang H-F, Peng R, Lu L, Li P-Q, Qiao B, Yang X-Y, Zheng Y-F, Wang H-Y, Gao Y-Q, Chen F-S. Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort. J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x. |
tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis
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Citation:
Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7 Epub:
Not Epub Abstract:
Angiogenesis requires co-ordination of multiple signalling inputs to regulate the behaviour of endothelial cells (ECs) as they... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN. tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis. Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7. |
A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
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Citation:
Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5 Epub:
Not Epub Abstract:
Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hadzhiev Y, Qureshi HK, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, Wragg JW, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvàgner G, Tora L, Gambus A, Fossey JS, Müller F. A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation. Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5. |
TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways
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Citation:
Am J Hum Genet. 2019 Feb 7;104(2):348-355. doi: 10.1016/j.ajhg.2018.12.016. Epub 2019 Jan 17 Epub:
Not Epub Abstract:
Steroid-resistant nephrotic syndrome (SRNS) is characterized by high-range proteinuria and most often focal and segmental... Organism or Cell Type:
zebrafish Citation Extract: Dorval G, Kuzmuk V, Gribouval O, Welsh GI, Bierzynska A, Schmitt A, Miserey-Lenkei S, Koziell A, Haq S, Benmerah A, Mollet G, Boyer O, Saleem MA, Antignac C.. TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways. Am J Hum Genet. 2019 Feb 7;104(2):348-355. doi: 10.1016/j.ajhg.2018.12.016. Epub 2019 Jan 17. |
Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model
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Citation:
Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x Epub:
Not Epub Abstract:
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality in humans mainly due to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A. Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model. Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x. |