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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Agonists of prostaglandin E2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies

Authors:
Garcia H, Serafin AS, Silbermann F, Porée E, Viau A, Mahaut C, Billot K, Birgy É, Garfa-Traore M, Roy S, Ceccarelli S, Mehraz M, Rodriguez PC, Deleglise B, Furio L, Jabot-Hanin F, Cagnard N, Del Nery E, Fila M, Sin-Monnot S, Antignac C, Lyonnet S, Krug P, Salomon R, Annereau J-P, Benmerah A, Delous M, Briseño-Roa L, Saunier S
Citation:
Proc Nat Acad Sci USA. 2022;[Epub] doi:10.1073/pnas.2115960119
Epub:
Yes
Abstract:
Nephronophthisis (NPH) is an autosomal recessive tubulointerstitial nephropathy belonging to the ciliopathy disorders and known...
Link:
https://www.pnas.org/doi/10.1073/pnas.2115960119
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garcia H, Serafin AS, Silbermann F, Porée E, Viau A, Mahaut C, Billot K, Birgy É, Garfa-Traore M, Roy S, Ceccarelli S, Mehraz M, Rodriguez PC, Deleglise B, Furio L, Jabot-Hanin F, Cagnard N, Del Nery E, Fila M, Sin-Monnot S, Antignac C, Lyonnet S, Krug P, Salomon R, Annereau J-P, Benmerah A, Delous M, Briseño-Roa L, Saunier S. Agonists of prostaglandin E2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies. Proc Nat Acad Sci USA. 2022;[Epub] doi:10.1073/pnas.2115960119.

The Giardia ventrolateral flange is a lamellar membrane protrusion that supports attachment

Authors:
Hardin WR, Alas GCM, Taparia N, Thomas EB, Steele-Ogus MC, Hvorecny KL, Halpern AR, Tůmová P, Kollman JM, Vaughan JC, Sniadecki NJ, Paredez AR
Citation:
PLoS Pathog. 2022;18(4):e1010496. doi:10.1371/journal.ppat.1010496
Epub:
Not Epub
Abstract:
Attachment to the intestinal epithelium is critical to the lifestyle of the ubiquitous parasite Giardia lamblia. The...
Link:
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010496
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Hardin WR, Alas GCM, Taparia N, Thomas EB, Steele-Ogus MC, Hvorecny KL, Halpern AR, Tůmová P, Kollman JM, Vaughan JC, Sniadecki NJ, Paredez AR. The Giardia ventrolateral flange is a lamellar membrane protrusion that supports attachment. PLoS Pathog. 2022;18(4):e1010496. doi:10.1371/journal.ppat.1010496.

Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction

Authors:
Weng S, Huebner RJ, Wallingford JB
Citation:
Cell Rep. 2022;39:110666. doi:10.1016/j.celrep.2022.110666
Epub:
Not Epub
Abstract:
Convergent extension (CE) is an evolutionarily conserved collective cell movement that elongates several organ systems during...
Link:
https://www.cell.com/cell-reports/pdf/S2211-1247(22)00418-1.pdf
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Weng S, Huebner RJ, Wallingford JB. Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction. Cell Rep. 2022;39:110666. doi:10.1016/j.celrep.2022.110666.

ARVCF catenin controls force production during vertebrate convergent extension

Authors:
Huebner RJ, Weng S, Lee C, Sarikaya S, Papoulas O, Cox RM, Marcotte EM, Wallingford JB
Citation:
Dev Cell. 2022;[Epub] doi:10.1016/j.devcel.2022.04.001
Epub:
Not Epub
Abstract:
The design of an animal’s body plan is encoded in the genome, and the execution of this program is a mechanical progression...
Link:
https://www.cell.com/developmental-cell/pdf/S1534-5807(22)00241-6.pdf
Organism or Cell Type:
Xenopus
Citation Extract:
Huebner RJ, Weng S, Lee C, Sarikaya S, Papoulas O, Cox RM, Marcotte EM, Wallingford JB. ARVCF catenin controls force production during vertebrate convergent extension. Dev Cell. 2022;[Epub] doi:10.1016/j.devcel.2022.04.001.

Left-right symmetry of zebrafish embryos requires somite surface tension

Authors:
Naganathan SR, Popović M, Oates AC
Citation:
Nature. 2022;[Epub ahead of print] doi:10.1038/s41586-022-04646-9
Epub:
Yes
Abstract:
The body axis of vertebrate embryos is periodically segmented into bilaterally symmetric pairs of somites2. The anteroposterior...
Link:
https://www.nature.com/articles/s41586-022-04646-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Naganathan SR, Popović M, Oates AC. Left-right symmetry of zebrafish embryos requires somite surface tension. Nature. 2022;[Epub ahead of print] doi:10.1038/s41586-022-04646-9.

FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells

Authors:
Yang SY, Hayer KE, Fazelinia H, Asnani M, Black KL, Naqvi AS, Pillai V, Spruce LA, Barash Y, Elenitoba-Johnson KSJ, Thomas-Tikhonenko A
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.24.489313
Epub:
Not Epub
Abstract:
Non-canonical exon usage plays many important roles in cellular phenotypes, but its contribution to human B-cell development...
Link:
https://www.biorxiv.org/content/10.1101/2022.04.24.489313v1
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: REH from B-Cell Acute Lymphoblastic Leukemia patients
Citation Extract:
Yang SY, Hayer KE, Fazelinia H, Asnani M, Black KL, Naqvi AS, Pillai V, Spruce LA, Barash Y, Elenitoba-Johnson KSJ, Thomas-Tikhonenko A. FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.24.489313.

Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health

Authors:
Sojan JM, Raman R, Muller M, Carnevali O, Renn J
Citation:
Int J Mol Sci. 2022; 23(9):4748. doi:10.3390/ijms23094748
Epub:
Not Epub
Abstract:
Zebrafish larvae, especially gene-specific mutants and transgenic lines, are increasingly used to study vertebrate skeletal...
Link:
https://www.mdpi.com/1422-0067/23/9/4748
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sojan JM, Raman R, Muller M, Carnevali O, Renn J. Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health. Int J Mol Sci. 2022; 23(9):4748. doi:10.3390/ijms23094748.

Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish

Authors:
Meier AB, Basheer F, Sertori R, Laird M, Liongue C, Ward AC
Citation:
Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110
Epub:
Not Epub
Abstract:
Background: Colony-stimulating factor 3 (CSF3), more commonly known as granulocyte colony-stimulating factor (G-CSF), acts via...
Link:
https://www.imrpress.com/journal/FBL/27/4/10.31083/j.fbl2704110/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meier AB, Basheer F, Sertori R, Laird M, Liongue C, Ward AC. Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish. Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110.

Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells

Authors:
Dierolf JG, Hunter HLM, Watson AJ, Betts DH
Citation:
Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print
Epub:
Not Epub
Abstract:
Cellular metabolism plays both an active and passive role in embryonic development, pluripotency, and cell-fate decisions....
Link:
https://www.liebertpub.com/doi/10.1089/scd.2021.0347
Delivery Method:
cell culture: murine embryonic stem cells
Citation Extract:
Dierolf JG, Hunter HLM, Watson AJ, Betts DH. Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells. Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print.

"Two-story building" of a ctenophore comb plate provides structural and functional integrity for motility of giant multicilia

Authors:
Jokura K, Sato Y, Shiba K, Inaba K
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.27.486007
Epub:
Not Epub
Abstract:
Comb plates (CPs) are large compound cilia uniquely seen in a basal metazoan group of ctenophores. Tens of thousands of cilia...
Link:
https://www.biorxiv.org/content/10.1101/2022.03.27.486007v1
Delivery Method:
microinjection
Organism or Cell Type:
Bolinopsis mikado (ctenophore)
Citation Extract:
Jokura K, Sato Y, Shiba K, Inaba K. "Two-story building" of a ctenophore comb plate provides structural and functional integrity for motility of giant multicilia. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.27.486007 .

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