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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Vitamin D receptor deficiency impairs inner ear development in zebrafish

Authors:
Kwon HJ
Citation:
Biochem Biophys Res Commun. 2016 Aug 12. pii: S0006-291X(16)31325-0. doi: 10.1016/j.bbrc.2016.08.070. [Epub ahead of print]
Epub:
Yes
Abstract:
The biological actions of vitamin D are largely mediated through binding to the vitamin D receptor (VDR), a member of the...
Organism or Cell Type:
zebrafish
Citation Extract:
Kwon HJ. Vitamin D receptor deficiency impairs inner ear development in zebrafish. Biochem Biophys Res Commun. 2016 Aug 12. pii: S0006-291X(16)31325-0. doi: 10.1016/j.bbrc.2016.08.070. [Epub ahead of print].

Zebrafish P54 RNA helicases are cytoplasmic granules residents that are required for development and stress resilience

Authors:
Zampedri C, Tinoco-Cuellar M, Carrillo-Rosas S, Diaz-Tellez A, Ramos-Balderas JL, Pelegri F, Maldonado E
Citation:
Biol Open. 2016 Aug 3. pii: bio.015826. doi: 10.1242/bio.015826. [Epub ahead of print]
Epub:
Yes
Abstract:
Stress granules are cytoplasmic foci that directly respond to the protein synthesis status of the cell. Various environmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zampedri C, Tinoco-Cuellar M, Carrillo-Rosas S, Diaz-Tellez A, Ramos-Balderas JL, Pelegri F, Maldonado E. Zebrafish P54 RNA helicases are cytoplasmic granules residents that are required for development and stress resilience. Biol Open. 2016 Aug 3. pii: bio.015826. doi: 10.1242/bio.015826. [Epub ahead of print].

Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish

Authors:
Powell R, Bubenshchikova E, Fukuyo Y, Hsu C, Lakiza O, Nomura H, Renfrew E, Garrity D, Obara T
Citation:
Mol Med Rep. 2016 Sep;14(3):2665-78. doi: 10.3892/mmr.2016.5550. Epub 2016 Jul 27
Epub:
Not Epub
Abstract:
Wilm's tumor 1 interacting protein (Wtip) was identified as an interacting partner of Wilm's tumor protein (WT1) in a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Powell R, Bubenshchikova E, Fukuyo Y, Hsu C, Lakiza O, Nomura H, Renfrew E, Garrity D, Obara T. Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish. Mol Med Rep. 2016 Sep;14(3):2665-78. doi: 10.3892/mmr.2016.5550. Epub 2016 Jul 27.

Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway

Authors:
Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, Chuang YJ
Citation:
J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9
Epub:
Not Epub
Abstract:
BACKGROUND: Development of neural and vascular systems displays astonishing similarities among vertebrates. This parallelism is...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, Chuang YJ. Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9.

An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells

Authors:
Jain HV, Beaucage SL
Citation:
Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1
Epub:
Not Epub
Abstract:
An innovative approach to the delivery of uncharged peptide nucleic acids (PNAs) and phosphorodiamidate morpholino (PMO)...
Organism or Cell Type:
cell culture: HeLa pLuc705
Citation Extract:
Jain HV, Beaucage SL. An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells. Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1.

[OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease

Authors:
Kreutz R, Schulz A, Meyer AM, Lorenzen T, Stoll M, Panakova D
Citation:
J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76
Epub:
Not Epub
Abstract:
OBJECTIVE: The Munich Wistar Frömter (MWF) rat represents a rat model for chronic kidney disease (CKD) with the development of...
Organism or Cell Type:
zebrafish
Citation Extract:
Kreutz R, Schulz A, Meyer AM, Lorenzen T, Stoll M, Panakova D. [OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease. J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76.

Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits

Authors:
Truszkowski TL, James EJ, Hasan M, Wishard TJ, Liu Z, Pratt KG, Cline HT, Aizenman CD
Citation:
Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7
Epub:
Not Epub
Abstract:
BACKGROUND: Fragile X Syndrome is the leading monogenetic cause of autism and most common form of intellectual disability....
Delivery Method:
brain injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Truszkowski TL, James EJ, Hasan M, Wishard TJ, Liu Z, Pratt KG, Cline HT, Aizenman CD. Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits. Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7.

Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function

Authors:
Kim D, Song J, Kang Y, Park S, Kim YI, Kwak S, Lim D, Park R, Chun CH, Choe SK, Jin EJ
Citation:
J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print]
Epub:
Yes
Abstract:
Cumulative evidence suggests the importance of organelle homeostasis in regulating metabolic functions in response to various...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim D, Song J, Kang Y, Park S, Kim YI, Kwak S, Lim D, Park R, Chun CH, Choe SK, Jin EJ. Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function. J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print].

Sec16 alternative splicing dynamically controls COPII transport efficiency

Authors:
Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, Preußner M, Heyd F
Citation:
Nat Commun. 2016 Aug 5;7:12347. doi: 10.1038/ncomms12347
Epub:
Not Epub
Abstract:
The transport of secretory proteins from the endoplasmic reticulum (ER) to the Golgi depends on COPII-coated vesicles. While...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Hek293 and HeLa and human peripheral blood mononuclear cells (PBMCs) enriched for T cells
Citation Extract:
Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, Preußner M, Heyd F. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016 Aug 5;7:12347. doi: 10.1038/ncomms12347.

Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice

Authors:
Wang M, Wu B, Tucker JD, Bollinger LE, Lu P, Lu Q
Citation:
Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. doi: 10.1038/mtna.2016.51
Epub:
Not Epub
Abstract:
A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated...
Delivery Method:
Endo-Porter, Polyethylenimine and Pluronic (PEAs)
Organism or Cell Type:
cell culture: C2C12E50, mdx mice
Citation Extract:
Wang M, Wu B, Tucker JD, Bollinger LE, Lu P, Lu Q. Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice. Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. doi: 10.1038/mtna.2016.51.

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