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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Recursive splicing in long vertebrate genes

Authors:
Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J
Citation:
Nature. 2015 May 21;521(7552):371-5. doi:10.1038/nature14466
Epub:
Not Epub
Abstract:
It is generally believed that splicing removes introns as single units from precursor messenger RNA transcripts. However, some...
Delivery Method:
Endo-porter, microinjection
Organism or Cell Type:
SH-SY5Y cells, zebrafish
Citation Extract:
Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J. Recursive splicing in long vertebrate genes. Nature. 2015 May 21;521(7552):371-5. doi:10.1038/nature14466.

GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1

Authors:
Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME
Citation:
Biochemical J. 2016;[Epub ahead of print] doi:10.1042/BCJ20160558
Epub:
Yes
Abstract:
Proper hematopoietic cell fate decisions require coordinated functions of transcription factors, their associated co-regulators...
Organism or Cell Type:
zebrafish
Citation Extract:
Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME. GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochemical J. 2016;[Epub ahead of print] doi:10.1042/BCJ20160558.

The endoderm indirectly influences morphogenetic movements of the zebrafish head kidney through the posterior cardinal vein and VegfC

Authors:
Chou CW, Hsu HC, You MS, Lin J, Liu YW
Citation:
Sci Rep. 2016 Aug 1;6:30677. doi: 10.1038/srep30677
Epub:
Not Epub
Abstract:
Integration of blood vessels and organ primordia determines organ shape and function. The head kidney in the zebrafish...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chou CW, Hsu HC, You MS, Lin J, Liu YW. The endoderm indirectly influences morphogenetic movements of the zebrafish head kidney through the posterior cardinal vein and VegfC. Sci Rep. 2016 Aug 1;6:30677. doi: 10.1038/srep30677.

The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/β-catenin activity during zebrafish dorsoventral axial patterning

Authors:
Wei S, Shang H, Cao Y, Wang Q
Citation:
J Genet Genomics. 2016 May 11. pii: S1673-8527(16)30051-0. doi: 10.1016/j.jgg.2016.05.003. [Epub ahead of print]
Epub:
Yes
Abstract:
The coiled-coil domain containing protein CCDC136 is a putative tumor suppressor and significantly down-regulated in gastric...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei S, Shang H, Cao Y, Wang Q. The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/β-catenin activity during zebrafish dorsoventral axial patterning. J Genet Genomics. 2016 May 11. pii: S1673-8527(16)30051-0. doi: 10.1016/j.jgg.2016.05.003. [Epub ahead of print].

Smad4 is required for the development of cardiac and skeletal muscle in zebrafish

Authors:
Yang J, Wang J, Zeng Z, Qiao L, Zhuang L, Jiang L, Wei J, Ma Q, Wu M, Ye S, Gao Q, Ma D, Huang X
Citation:
Differentiation. 2016 Jul 28. pii: S0301-4681(15)30076-1. doi: 10.1016/j.diff.2016.06.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Transforming growth factor-beta (TGF-beta) regulates cellular functions and plays key roles in development and carcinogenesis....
Organism or Cell Type:
zebrafish
Citation Extract:
Yang J, Wang J, Zeng Z, Qiao L, Zhuang L, Jiang L, Wei J, Ma Q, Wu M, Ye S, Gao Q, Ma D, Huang X. Smad4 is required for the development of cardiac and skeletal muscle in zebrafish. Differentiation. 2016 Jul 28. pii: S0301-4681(15)30076-1. doi: 10.1016/j.diff.2016.06.005. [Epub ahead of print].

MAPK signaling is necessary for neurogenesis in Nematostella vectensis

Authors:
Layden MJ, Johnston H, Amiel AR, Havrilak J, Steinworth B, Chock T, Röttinger E, Martindale MQ
Citation:
BMC Biology. 2016;14:61. doi:10.1186/s12915-016-0282-1
Epub:
Not Epub
Abstract:
Background: The nerve net of Nematostella is generated using a conserved cascade of neurogenic transcription factors. For...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Layden MJ, Johnston H, Amiel AR, Havrilak J, Steinworth B, Chock T, Röttinger E, Martindale MQ. MAPK signaling is necessary for neurogenesis in Nematostella vectensis. BMC Biology. 2016;14:61. doi:10.1186/s12915-016-0282-1.

Eph and Ephrin function in Dispersal and Epithelial Insertion of Pigmented Immunocytes in Sea Urchin Embryos

Authors:
Krupke O, Zysk I, Mellott D, Burke RD
Citation:
eLife. 2016;10.7554/eLife.16000 doi:10.7554/eLife.16000
Epub:
Not Epub
Abstract:
The mechanisms that underlie directional cell migration are incompletely understood. Eph receptors usually guide migrations of...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Krupke O, Zysk I, Mellott D, Burke RD. Eph and Ephrin function in Dispersal and Epithelial Insertion of Pigmented Immunocytes in Sea Urchin Embryos. eLife. 2016;10.7554/eLife.16000 doi:10.7554/eLife.16000.

Characterization of the POU5F1 homologue in Nile tilapia: from expression pattern to biological activity

Authors:
Huang X, Zhao Y, Liu L, Fan Z, Zhou L, Wang Z, Wei L, Wang D, Wei J
Citation:
Stem Cells Dev. 2016 Jul 29. [Epub ahead of print]
Epub:
Yes
Abstract:
POU5F1 (OCT4) is a crucial transcription factor for induction and maintenance of cellular pluripotency as well as survival of...
Organism or Cell Type:
Oreochromis niloticus (Nile tilapia)
Citation Extract:
Huang X, Zhao Y, Liu L, Fan Z, Zhou L, Wang Z, Wei L, Wang D, Wei J. Characterization of the POU5F1 homologue in Nile tilapia: from expression pattern to biological activity. Stem Cells Dev. 2016 Jul 29. [Epub ahead of print].

Loss of mtch2 function impairs early development of liver, intestine and visceral adipocytes in zebrafish larvae

Authors:
Landgraf K, Strobach A, Kiess W, Körner A
Citation:
FEBS Lett. 2016 Jul 28. doi: 10.1002/1873-3468.12330. [Epub ahead of print]
Epub:
Yes
Abstract:
The mitochondrial carrier homolog 2 (MTCH2) has been shown to be essential for embryogenesis in mice, and variants in the MTCH2...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landgraf K, Strobach A, Kiess W, Körner A. Loss of mtch2 function impairs early development of liver, intestine and visceral adipocytes in zebrafish larvae. FEBS Lett. 2016 Jul 28. doi: 10.1002/1873-3468.12330. [Epub ahead of print].

Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1

Authors:
Fraszczak J, Helness A, Chen R, Vadnais C, Robert F, Khandanpour C, Möröy T
Citation:
PLoS One. 2016;11(7):e0160344. doi:10.1371/journal.pone.0160344
Epub:
Not Epub
Abstract:
A regulatory circuit that controls myeloid versus B lymphoid cell fate in hematopoietic progenitors has been proposed, in which...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: LSK cells (B cell progenitors)
Citation Extract:
Fraszczak J, Helness A, Chen R, Vadnais C, Robert F, Khandanpour C, Möröy T. Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1. PLoS One. 2016;11(7):e0160344. doi:10.1371/journal.pone.0160344.

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