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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12184 scientific papers returned from the database with the search filters currently being used below.

Mucociliary Wnt signaling promotes cilia biogenesis and beating

Authors:
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C
Citation:
Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2
Epub:
Not Epub
Abstract:
It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile cilia are signaling-inert...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Mucociliary Wnt signaling promotes cilia biogenesis and beating. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2.

Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis

Authors:
Murayama E, Vivier C, Schmidt A, Herbomel P
Citation:
Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y
Epub:
Not Epub
Abstract:
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murayama E, Vivier C, Schmidt A, Herbomel P. Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis. Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y.

sox1a:eGFP transgenic line and single-cell transcriptomics reveal the origin of zebrafish intraspinal serotonergic neurons

Authors:
Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S
Citation:
iScience. 2023 Jul 11;26(8):107342. doi: 10.1016/j.isci.2023.107342. PMID: 37529101; PMCID: PMC10387610
Epub:
Not Epub
Abstract:
Sox transcription factors are crucial for vertebrate nervous system development. In zebrafish embryo, sox1 genes are expressed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S. sox1a:eGFP transgenic line and single-cell transcriptomics reveal the origin of zebrafish intraspinal serotonergic neurons. iScience. 2023 Jul 11;26(8):107342. doi: 10.1016/j.isci.2023.107342. PMID: 37529101; PMCID: PMC10387610.

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia

Authors:
Kim J, Park EA, Shin MY, Park SJ
Citation:
Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print
Epub:
Not Epub
Abstract:
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that control the eukaryotic cell cycle. Limited information is...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Kim J, Park EA, Shin MY, Park SJ. Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia. Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print.

YULINK regulates vascular formation in zebrafish and HUVECs

Authors:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J
Citation:
Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8
Epub:
Not Epub
Abstract:
Background: The distinct arterial and venous cell fates are dictated by a combination of various genetic factors which form...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J. YULINK regulates vascular formation in zebrafish and HUVECs. Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8.

In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery

Authors:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL
Citation:
ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print
Epub:
Yes
Abstract:
Peptide-mediated delivery of macromolecules in cells has significant potential therapeutic benefits, but no therapy employing...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL. In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print.

Mob4 is required for neurodevelopment in zebrafish

Authors:
Florindo C, Mimoso JM, Palma SL, Gonçalves C, Silvestre D, Campinho M, Tavares A
Citation:
microPublication Biology. 2023. 10.17912/micropub.biology.000762
Epub:
Not Epub
Abstract:
Mob4 is an essential evolutionary conserved protein shown to play roles in cell division and neural development. Mob4 is a core...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Florindo C, Mimoso JM, Palma SL, Gonçalves C, Silvestre D, Campinho M, Tavares A. Mob4 is required for neurodevelopment in zebrafish. microPublication Biology. 2023. 10.17912/micropub.biology.000762.

Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish

Authors:
Khatri D, Putoux A, Cologne A, Kaltenbach S, Besson A, Bertiaux E, Guguin J, Fendler A, Dupont MA, Benoit-Pilven C, Qebibo L, Ahmed-Elie S, Audebert-Bellanger S, Blanc P, Rambaud T, Castelle M, Cornen G, Grotto S, Guët A, Guibaud L, Michot C, Odent S, Ruaud L, Sacaze E, Hamel V, Bordonné R, Leutenegger AL, Edery P, Burglen L, Attié-Bitach T, Mazoyer S, Delous M
Citation:
Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2102569120. doi: 10.1073/pnas.2102569120. Epub 2023 Feb 21
Epub:
Not Epub
Abstract:
In the human genome, about 750 genes contain one intron excised by the minor spliceosome. This spliceosome comprises its own...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khatri D, Putoux A, Cologne A, Kaltenbach S, Besson A, Bertiaux E, Guguin J, Fendler A, Dupont MA, Benoit-Pilven C, Qebibo L, Ahmed-Elie S, Audebert-Bellanger S, Blanc P, Rambaud T, Castelle M, Cornen G, Grotto S, Guët A, Guibaud L, Michot C, Odent S, Ruaud L, Sacaze E, Hamel V, Bordonné R, Leutenegger AL, Edery P, Burglen L, Attié-Bitach T, Mazoyer S, Delous M. Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2102569120. doi: 10.1073/pnas.2102569120. Epub 2023 Feb 21.

Quantifying endothelial cell proliferation in the zebrafish embryo

Authors:
Bowley G, Chico TJ, Serbanovic-Canic J, Evans PC
Citation:
F1000Res. 2021 Oct 11;10:1032. doi: 10.12688/f1000research.73130.1. eCollection 2021
Epub:
Not Epub
Abstract:
Introduction: Endothelial cell (EC) proliferation is a fundamental determinant of vascular development and homeostasis, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bowley G, Chico TJ, Serbanovic-Canic J, Evans PC. Quantifying endothelial cell proliferation in the zebrafish embryo. F1000Res. 2021 Oct 11;10:1032. doi: 10.12688/f1000research.73130.1. eCollection 2021.

Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney

Authors:
Wesselman HM, Gatz AE, Pfaff MR, Arceri L, Wingert RA
Citation:
Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666
Epub:
Not Epub
Abstract:
Despite significant advances in understanding nephron segment patterning, many questions remain about the underlying genes and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wesselman HM, Gatz AE, Pfaff MR, Arceri L, Wingert RA. Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666.

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