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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish
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Citation:
JoVE. 2017;122:e55213. doi:10.3791/55213 Epub:
Not Epub Abstract:
Cellular events that take place during the earliest stages of animal embryonic development are driven by maternally derived... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Welch EL, Eno CC, Nair S, Lindeman RE, Pelegri F. Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish. JoVE. 2017;122:e55213. doi:10.3791/55213. |
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity
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Citation:
Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print] Epub:
Yes Abstract:
Vascular integrity helps maintain brain microenvironment homeostasis, which is critical for the normal development and function... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL. Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity. Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print]. |
CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions
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Citation:
Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. PMID: 28428220 Epub:
Yes Abstract:
Objective: Decrease in VE-cadherin adherens junctions reduces vascular stability, whereas disruption of adherens junctions is a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C. CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. PMID: 28428220. |
Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor
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Citation:
Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487 Epub:
Yes Abstract:
Here we demonstrate a phosphorodiamidate morpholino oligos (PMO)-functionlized nanochannel biosensor for label-free detection... Citation Extract: Liao T, Li X, Tong Q, Zou K, Zhang H, Tang L, Sun Z, Zhang G-J. Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor. Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487. |
Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation
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Citation:
PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296 Epub:
Not Epub Abstract:
Gonad morphogenesis relies on the correct spatiotemporal expression of a number of genes that together fulfill the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse gonad explants Citation Extract: Rudigier LJ, Dame C, Scholz H, Kirschner KM. Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation. PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296. |
Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy
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Citation:
PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744 Epub:
Not Epub Abstract:
Degeneration and loss of lower motor neurons is the major pathological hallmark of spinal muscular atrophy (SMA), resulting... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Boyd PJ, Tu W-Y, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH. Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744. |
Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain
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Citation:
PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573 Epub:
Not Epub Abstract:
All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573. |
An Integrative Developmental Genomics and Systems Biology Approach To Identify An In Vivo Sox Trio-Mediated Gene Regulatory Network In Murine Embryos
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Citation:
BioMed Res Internat. 2017;[Epub ahead of print] Epub:
Yes Abstract:
Embryogenesis is an intricate process involving multiple genes and pathways. Some of the key transcription factors controlling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PP, Prabhakar S, Lufkin T. An Integrative Developmental Genomics and Systems Biology Approach To Identify An In Vivo Sox Trio-Mediated Gene Regulatory Network In Murine Embryos. BioMed Res Internat. 2017;[Epub ahead of print] . |
A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder
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Citation:
Molec Psychiatry. 2017;[Epub ahead of print] doi:10.1038/mp.2017.74 Epub:
Yes Abstract:
Impaired executive inhibition is a core deficit of attention deficit hyperactivity disorder (ADHD), which is a common childhood... Organism or Cell Type:
zebrafish Citation Extract: Yang L, Chang S, Lu Q, Zhang Y, Wu Z, Sun X, Cao Q, Qian Y, Jia T, Xu B, Duan Q, Li Y, Zhang K, Schumann G, Liu D, Wang J, Wang Y, Lu L. A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder. Molec Psychiatry. 2017;[Epub ahead of print] doi:10.1038/mp.2017.74. |
Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos
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Citation:
bioRxiv. 2017;doi:10.1101/125716 Epub:
Not Epub Abstract:
Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Joseph SR, Pálfy M, Hilbert L, Kumar M, Karschau J, Zaburdaev V, Shevchenko A, Vastenhouw NL. Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos. bioRxiv. 2017;doi:10.1101/125716. |