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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
The enteric nervous system promotes intestinal health by constraining microbiota composition
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Citation:
PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689 Epub:
Not Epub Abstract:
Sustaining a balanced intestinal microbial community is critical for maintaining intestinal health and preventing chronic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rolig AS, Mittge EK, Ganz J, Troll JV, Melancon E, Wiles TJ, Alligood K, Stephens WZ, Eisen JS, Guillemin K. The enteric nervous system promotes intestinal health by constraining microbiota composition. PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689. |
Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency
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Citation:
J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. PMID: 28216435; PMCID: PMC7126384 Epub:
Yes Abstract:
An adult with hypomorphic ZAP-70 deficiency due to de novo donor splice site mutation manifested autoimmunity, infections... Citation Extract: Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong MC, Cohen-Blanchet A, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC. Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency. J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. PMID: 28216435; PMCID: PMC7126384. |
Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish
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Citation:
bioRxiv. 2017. doi:10.1101/108779 Epub:
Yes Abstract:
Notch signaling plays an essential role in the proliferation, differentiation and cell fate determination of various tissues,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Veen M, van Pelt J, Mans LA, Moolenaar WH, Haramis A-PG. Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish. bioRxiv. 2017. doi:10.1101/108779. |
Mechanical stretch triggers rapid epithelial cell division through Piezo1
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Citation:
Nature. 2017;543:118–121. doi:10.1038/nature21407 Epub:
Yes Abstract:
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J. Mechanical stretch triggers rapid epithelial cell division through Piezo1. Nature. 2017;543:118–121. doi:10.1038/nature21407. |
The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection
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Citation:
Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185 Epub:
Not Epub Abstract:
Effective recognition of viral components and the subsequent stimulation of the production of type I interferons (IFNs) is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
BALB/c mice Citation Extract: Hazra B, Kumawat KL, Basu A. The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection. Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185. |
Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction
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Citation:
Sci Rep. 2017;7:42583. doi:10.1038/srep42583 Epub:
Not Epub Abstract:
The human ubiquitous protein cystinosin is responsible for transporting the disulphide amino acid cystine from the lysosomal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E. Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction. Sci Rep. 2017;7:42583. doi:10.1038/srep42583. |
Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling
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Citation:
Sci Rep. 2017;7:42590 doi:10.1038/srep42590 Epub:
Not Epub Abstract:
The Tcf/Lef family of transcription factors mediates the Wnt/β-catenin pathway that is involved in a wide range of biological... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Han W, Lee H, Han J-K. Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling. Sci Rep. 2017;7:42590 doi:10.1038/srep42590. |
Dual roles of Akirin2 during Xenopus neural development
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Citation:
J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print] Epub:
Yes Abstract:
To ensure correct spatial and temporal patterning, embryos must maintain pluripotent cell populations and control when cells... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B. Dual roles of Akirin2 during Xenopus neural development. J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print]. |
Snail2 and Zeb2 repress P-Cadherin to define embryonic territories in the chick embryo
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Citation:
Development. 2017 Jan 13. pii: dev.142562. doi: 10.1242/dev.142562. [Epub ahead of print] Epub:
Not Epub Abstract:
Snail and Zeb transcription factors induce epithelial to mesenchymal transition (EMT) in embryonic and adult tissues by direct... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Acloque H, Ocaña OH, Abad D, Stern CD, Nieto MA. Snail2 and Zeb2 repress P-Cadherin to define embryonic territories in the chick embryo. Development. 2017 Jan 13. pii: dev.142562. doi: 10.1242/dev.142562. [Epub ahead of print]. |
Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography
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Citation:
Sci Rep. 2017;7:42506. doi:10.1038/srep42506 Epub:
Not Epub Abstract:
Birth defects affect 3% of children in the United States. Among the birth defects, congenital heart disease and craniofacial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Deniz E, Jonas S, Hooper M, Griffin JN, Choma MA, Khokha MF. Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography. Sci Rep. 2017;7:42506. doi:10.1038/srep42506. |