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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease)

Authors:
Wager K, Zdebik AA, Fu S, Cooper JD, Harvey RJ, Russell C
Citation:
PLoS One. 2016 Jun 21;11(6):e0157365. doi: 10.1371/journal.pone.0157365. eCollection 2016
Epub:
Not Epub
Abstract:
The neuronal ceroid lipofuscinoses are a group of lysosomal storage disorders that comprise the most common, genetically...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157365
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wager K, Zdebik AA, Fu S, Cooper JD, Harvey RJ, Russell C. Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease). PLoS One. 2016 Jun 21;11(6):e0157365. doi: 10.1371/journal.pone.0157365. eCollection 2016.

Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α

Authors:
Lien HW, Yuan RY, Chou CM, Chen YC, Hung CC, Hu CH, Hwang SP, Hwang PP, Shen CN, Chen CL, Cheng CH, Huang CJ
Citation:
Sci Rep. 2016 Jun 21;6:28297. doi: 10.1038/srep28297
Epub:
Not Epub
Abstract:
Cyclins play a central role in cell-cycle regulation; in mammals, the D family of cyclins consists of cyclin D1, D2, and D3. In...
Link:
http://www.nature.com/articles/srep28297
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lien HW, Yuan RY, Chou CM, Chen YC, Hung CC, Hu CH, Hwang SP, Hwang PP, Shen CN, Chen CL, Cheng CH, Huang CJ. Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α. Sci Rep. 2016 Jun 21;6:28297. doi: 10.1038/srep28297.

IFT46 plays crucial roles in craniofacial and cilia development

Authors:
Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS
Citation:
Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)31001-4. doi: 10.1016/j.bbrc.2016.06.083. [Epub ahead of print]
Epub:
Yes
Abstract:
The intraflagellar transport (IFT) system is essential for bidirectional movement of ciliary components from the basal body to...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16310014
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS. IFT46 plays crucial roles in craniofacial and cilia development. Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)31001-4. doi: 10.1016/j.bbrc.2016.06.083. [Epub ahead of print].

Beneficial roles of melanoma cell adhesion molecule in spinal cord transection recovery in adult zebrafish

Authors:
Liu CJ, Xie L, Cui C, Chu M, De Zhao H, Yao L, Li YH, Schachner M, Shen YQ
Citation:
J Neurochem. 2016 Jun 18. doi: 10.1111/jnc.13707. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Melanoma cell adhesion molecule (MCAM) is a multifunctional protein involved in miscellaneous processes, including development...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/jnc.13707/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Liu CJ, Xie L, Cui C, Chu M, De Zhao H, Yao L, Li YH, Schachner M, Shen YQ. Beneficial roles of melanoma cell adhesion molecule in spinal cord transection recovery in adult zebrafish. J Neurochem. 2016 Jun 18. doi: 10.1111/jnc.13707. [Epub ahead of print].

Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity

Authors:
Eichner R, Heider M, Fernández-Sáiz V, van Bebber F, Garz AK, Lemeer S, Rudelius M, Targosz BS, Jacobs L, Knorn AM, Slawska J, Platzbecker U, Germing U, Langer C, Knop S, Einsele H, Peschel C, Haass C, Keller U, Schmid B, Götze KS, Kuster B, Bassermann F
Citation:
Nat Med. 2016 Jun 13. doi: 10.1038/nm.4128. [Epub ahead of print]
Epub:
Yes
Abstract:
Immunomodulatory drugs (IMiDs), such as thalidomide and its derivatives lenalidomide and pomalidomide, are key treatment...
Link:
http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4128.html
Organism or Cell Type:
zebrafish
Citation Extract:
Eichner R, Heider M, Fernández-Sáiz V, van Bebber F, Garz AK, Lemeer S, Rudelius M, Targosz BS, Jacobs L, Knorn AM, Slawska J, Platzbecker U, Germing U, Langer C, Knop S, Einsele H, Peschel C, Haass C, Keller U, Schmid B, Götze KS, Kuster B, Bassermann F. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016 Jun 13. doi: 10.1038/nm.4128. [Epub ahead of print].

Epigenetic activation of Sox2 gene in the developing vertebrate neural plate

Authors:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH
Citation:
Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20
Epub:
Not Epub
Abstract:
One of the earliest manifestations of neural induction is onset of expression of the neural marker Sox2, mediated by the...
Link:
http://www.molbiolcell.org/content/27/12/1921.abstract
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH. Epigenetic activation of Sox2 gene in the developing vertebrate neural plate. Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20.

Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells

Authors:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T
Citation:
Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595
Epub:
Yes
Abstract:
Purpose: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive human T-cell malignancy induced by human T-lymphotrophic virus-...
Link:
https://aacrjournals.org/clincancerres/article/22/23/5915/122959/Dysregulation-of-c-Myb-Pathway-by-Aberrant
Organism or Cell Type:
cell culture: adult T-cell leukemia/lymphoma cells
Citation Extract:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T. Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells. Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595.

A novel function of calcitonin gene-related peptide in body fluid Cl− homeostasis

Authors:
Wang Y-F, Lafont A-G, Lee Y-C, Hwang P-P
Citation:
Proc Royal Soc B Biol. 2016;[Epub ahead of print] doi:10.1098/rspb.2016.0684
Epub:
Yes
Abstract:
Vertebrates need to maintain extracellular chloride (Cl−) concentrations to ensure the normal operation of physiological...
Link:
http://rspb.royalsocietypublishing.org/content/283/1832/20160684
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y-F, Lafont A-G, Lee Y-C, Hwang P-P. A novel function of calcitonin gene-related peptide in body fluid Cl− homeostasis. Proc Royal Soc B Biol. 2016;[Epub ahead of print] doi:10.1098/rspb.2016.0684.

Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos

Authors:
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM
Citation:
Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi:10.1289/EHP141
Epub:
Yes
Abstract:
Exposure to the commonly used dithiocarbamate (DTC) pesticide ziram is associated with an increased risk of developing...
Link:
http://ehp.niehs.nih.gov/EHP141/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM. Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos. Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi:10.1289/EHP141.

Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated α-dystroglycan

Authors:
Marchese M, Pappalardo A, Baldacci J, Verri T, Doccini S, Cassandrini D, Bruno C, Fiorillo C, Garcia-Gil M, Bertini E, Pitto L, Santorelli FM
Citation:
Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30951-2. doi: 10.1016/j.bbrc.2016.06.033. [Epub ahead of print]
Epub:
Yes
Abstract:
Defective dolichol-phosphate mannose synthase (DPMS) complex is a rare cause of congenital muscular dystrophy associated with...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16309512
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marchese M, Pappalardo A, Baldacci J, Verri T, Doccini S, Cassandrini D, Bruno C, Fiorillo C, Garcia-Gil M, Bertini E, Pitto L, Santorelli FM. Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated α-dystroglycan. Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30951-2. doi: 10.1016/j.bbrc.2016.06.033. [Epub ahead of print].

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