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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential

Authors:
Cator LJ, Pietri JE, Murdock CC, Ohm JR, Lewis EE, Read AF, Luckhart S, Thomas MB
Citation:
Sci Rep. 2015;5:11947 doi:10.1038/srep11947
Epub:
Not Epub
Abstract:
Malaria parasites alter mosquito feeding behaviour in a way that enhances parasite transmission. This is widely considered a...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Anopheles stephensi (mosquito)
Citation Extract:
Cator LJ, Pietri JE, Murdock CC, Ohm JR, Lewis EE, Read AF, Luckhart S, Thomas MB. Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential. Sci Rep. 2015;5:11947 doi:10.1038/srep11947.

Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome

Authors:
Rapchak CE, Patel N, Hudson J, Crawford M
Citation:
Biochem Cell Biol. 2015 May 25:1-9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The polo-like kinases are a family of conserved serine/threonine kinases that play multiple roles in regulation of the cell...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rapchak CE, Patel N, Hudson J, Crawford M. Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome. Biochem Cell Biol. 2015 May 25:1-9. [Epub ahead of print].

A conserved role of αA-crystallin in the development of the zebrafish embryonic lens

Authors:
Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS
Citation:
Exp Eye Res. 2015 Jul 3. pii: S0014-4835(15)00220-1. doi: 10.1016/j.exer.2015.07.001. [Epub ahead of print]
Epub:
Yes
Abstract:
αA- and αB-crystallins are small heat shock proteins that bind thermodynamically destabilized proteins thereby inhibiting their...
Organism or Cell Type:
zebrafish
Citation Extract:
Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS. A conserved role of αA-crystallin in the development of the zebrafish embryonic lens. Exp Eye Res. 2015 Jul 3. pii: S0014-4835(15)00220-1. doi: 10.1016/j.exer.2015.07.001. [Epub ahead of print].

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

Authors:
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L
Citation:
PNAS. 2015;112(27):E3495-E3504. doi:10.1073/pnas.1507105112
Epub:
Not Epub
Abstract:
Damage repair mechanisms at transcriptionally active sites during the G0/G1 phase are largely unknown. To elucidate these...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination. PNAS. 2015;112(27):E3495-E3504. doi:10.1073/pnas.1507105112.

In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress

Authors:
Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE
Citation:
PLoS Genet. 2015;11(7):e1005349. doi:10.1371/journal.pgen.1005349
Epub:
Not Epub
Abstract:
African Americans have a disproportionate risk for developing nephropathy. This disparity has been attributed to coding...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson BR, Howell DN, Soldano K, Garrett ME, Katsanis N, Telen MJ, Davis EE, Ashley-Koch AE. In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. PLoS Genet. 2015;11(7):e1005349. doi:10.1371/journal.pgen.1005349.

Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse

Authors:
McGovern VL, Massoni-Laporte A, Wang X, Le TT, Le HT, Beattie CE, Rich MM, Burghes AH
Citation:
PLoS One. 2015 Jul 2;10(7):e0132364. doi: 10.1371/journal.pone.0132364. eCollection 2015
Epub:
Not Epub
Abstract:
Spinal muscular atrophy is caused by loss of the SMN1 gene and retention of SMN2. The SMN2 copy number inversely correlates...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McGovern VL, Massoni-Laporte A, Wang X, Le TT, Le HT, Beattie CE, Rich MM, Burghes AH. Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse. PLoS One. 2015 Jul 2;10(7):e0132364. doi: 10.1371/journal.pone.0132364. eCollection 2015.

Zebrafish Wnt9b Patterns the First Pharyngeal Arch into D-I-V Domains and Promotes Anterior-Medial Outgrowth

Authors:
Jackson HW, Prakash D, Litaker M, Ferreira T, Jezewski PA
Citation:
Am J Molec Biol. 2015;5(3):[Epub] doi:10.4236/ajmb.2015.53006
Epub:
Yes
Abstract:
Disrupted morphogenesis and growth of the embryonic maxillary jaw leads to oral facial clefting in humans (OFC) and results in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jackson HW, Prakash D, Litaker M, Ferreira T, Jezewski PA. Zebrafish Wnt9b Patterns the First Pharyngeal Arch into D-I-V Domains and Promotes Anterior-Medial Outgrowth. Am J Molec Biol. 2015;5(3):[Epub] doi:10.4236/ajmb.2015.53006.

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction

Authors:
Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang HC, Zon LI, Zhou Y, Chen S, Pan W
Citation:
Cell Res. 2015 Jul 3. doi: 10.1038/cr.2015.81. [Epub ahead of print]
Epub:
Yes
Abstract:
Dysregulation of ribosome biogenesis causes human diseases, such as Diamond-Blackfan anemia, del (5q-) syndrome and bone marrow...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang HC, Zon LI, Zhou Y, Chen S, Pan W. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Res. 2015 Jul 3. doi: 10.1038/cr.2015.81. [Epub ahead of print].

Lack of phosphomannomutase 2 affects Xenopus laevis morphogenesis and the non-canonical Wnt5a/Ror2 signalling

Authors:
Himmelreich N, Kaufmann LT, Steinbeisser H, Körner C, Thiel C
Citation:
J Inherit Metab Dis. 2015 Jul 4. [Epub ahead of print]
Epub:
Yes
Abstract:
Reduced phosphomannomutase 2 activity in man leads to hypoglycosylation of glycoconjugates causing PMM2-CDG, the most common...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Himmelreich N, Kaufmann LT, Steinbeisser H, Körner C, Thiel C. Lack of phosphomannomutase 2 affects Xenopus laevis morphogenesis and the non-canonical Wnt5a/Ror2 signalling. J Inherit Metab Dis. 2015 Jul 4. [Epub ahead of print].

Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway

Authors:
Antunes AT, Goos YJ, Pereboom TC, Hermkens D, Wlodarski MW, Da Costa L, MacInnes AW
Citation:
PLoS Genet. 2015;11(7):e1005326. doi:10.1371/journal.pgen.1005326
Epub:
Not Epub
Abstract:
Mutations in ribosomal protein (RP) genes can result in the loss of erythrocyte progenitor cells and cause severe anemia. This...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Antunes AT, Goos YJ, Pereboom TC, Hermkens D, Wlodarski MW, Da Costa L, MacInnes AW. Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway. PLoS Genet. 2015;11(7):e1005326. doi:10.1371/journal.pgen.1005326.

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