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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions

Authors:
Wincent E, Stegeman JJ, Jönsson ME
Citation:
Toxicol Appl Pharmacol. 2015 Feb 21. pii: S0041-008X(15)00065-4. doi: 10.1016/j.taap.2015.02.014. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling regulates essential biological functions and acts in developmental toxicity of some chemicals. The aryl...
Organism or Cell Type:
zebrafish
Citation Extract:
Wincent E, Stegeman JJ, Jönsson ME. Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions. Toxicol Appl Pharmacol. 2015 Feb 21. pii: S0041-008X(15)00065-4. doi: 10.1016/j.taap.2015.02.014. [Epub ahead of print].

Angiopoietin-like proteins stimulate HSPC development through interaction with Notch receptor signaling

Authors:
Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, Bernstein ID, Aster JC, White RM, Zon LI
Citation:
Elife. 2015 Feb 25;4. doi: 10.7554/eLife.05544. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Angiopoietin-like proteins (angptls) are capable of ex vivo expansion of mouse and human hematopoietic stem and progenitor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, Bernstein ID, Aster JC, White RM, Zon LI. Angiopoietin-like proteins stimulate HSPC development through interaction with Notch receptor signaling. Elife. 2015 Feb 25;4. doi: 10.7554/eLife.05544. [Epub ahead of print].

Effects of low-dose ionizing radiation and menadione, an inducer of oxidative stress, alone and in combination in a vertebrate embryo model

Authors:
Bladen CL, Kozlowski DJ, Dynan WS
Citation:
Radiat Res. 2012 Nov;178(5):499-503. doi: 10.1667/RR3042.2. Epub 2012 Oct 23
Epub:
Not Epub
Abstract:
Prior work has established the zebrafish embryo as an in vivo model for studying the biological effects of exposure to low...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bladen CL, Kozlowski DJ, Dynan WS. Effects of low-dose ionizing radiation and menadione, an inducer of oxidative stress, alone and in combination in a vertebrate embryo model. Radiat Res. 2012 Nov;178(5):499-503. doi: 10.1667/RR3042.2. Epub 2012 Oct 23.

The TORC2 Component, Sin1, Controls Migration of Anterior Mesendoderm during Zebrafish Gastrulation

Authors:
Dumortier JG, David NB
Citation:
PLoS ONE. 2015;10(2):e0118474. doi:10.1371/journal.pone.0118474
Epub:
Not Epub
Abstract:
TORC2 is a serine-threonine kinase complex conserved through evolution that recently emerged as a new regulator of actin...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dumortier JG, David NB. The TORC2 Component, Sin1, Controls Migration of Anterior Mesendoderm during Zebrafish Gastrulation. PLoS ONE. 2015;10(2):e0118474. doi:10.1371/journal.pone.0118474.

Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos

Authors:
Piacentino ML, Ramachandran J, Bradham CA
Citation:
Development. 2015 Jan 29. pii: dev.114322. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal patterning in the sea urchin embryo requires a conversation between the skeletogenic primary mesenchyme cells (PMCs)...
Delivery Method:
microinjection
Organism or Cell Type:
Lytechinus variegatus (sea urchin)
Citation Extract:
Piacentino ML, Ramachandran J, Bradham CA. Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos. Development. 2015 Jan 29. pii: dev.114322. [Epub ahead of print].

Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function

Authors:
Paolini A, Duchemin AL, Albadri S, Patzel E, Bornhorst D, González Avalos P, Lemke S, Machate A, Brand M, Sel S, Di Donato V, Del Bene F, Zolessi FR, Ramialison M, Poggi L
Citation:
Development. 2015 Feb 5. pii: dev.118612. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Divisions that generate one neuronal lineage-committed and one self-renewing cell maintain the balance of proliferation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paolini A, Duchemin AL, Albadri S, Patzel E, Bornhorst D, González Avalos P, Lemke S, Machate A, Brand M, Sel S, Di Donato V, Del Bene F, Zolessi FR, Ramialison M, Poggi L. Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function. Development. 2015 Feb 5. pii: dev.118612. [Epub ahead of print].

P16 is an essential regulator of skeletogenesis in the sea urchin embryo

Authors:
Cheers MS, Ettensohn CA
Citation:
Dev Biol. 2005;283(2):384-96
Epub:
Not Epub
Abstract:
The primary mesenchyme cells (PMCs) of the sea urchin embryo undergo a dramatic sequence of morphogenetic behaviors that...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Cheers MS, Ettensohn CA. P16 is an essential regulator of skeletogenesis in the sea urchin embryo. Dev Biol. 2005;283(2):384-96.

A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium

Authors:
Thomas S, Wright KJ, Le Corre S, Micalizzi A, Romani M, Abhyankar A, Saada J, Perrault I, Amiel J, Litzler J, Filhol E, Elkhartoufi N, Kwong M, Casanova JL, Boddaert N, Baehr W, Lyonnet S, Munnich A, Burglen L, Chassaing N, Encha-Ravazi F, Vekemans M, Gleeson JG, Valente EM, Jackson PK, Drummond IA, Saunier S, Attié-Bitach T
Citation:
Hum Mutat. 2014 Jan;35(1):137-46
Epub:
Not Epub
Abstract:
Joubert syndrome (JS) is characterized by a distinctive cerebellar structural defect, namely the << molar tooth sign...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thomas S, Wright KJ, Le Corre S, Micalizzi A, Romani M, Abhyankar A, Saada J, Perrault I, Amiel J, Litzler J, Filhol E, Elkhartoufi N, Kwong M, Casanova JL, Boddaert N, Baehr W, Lyonnet S, Munnich A, Burglen L, Chassaing N, Encha-Ravazi F, Vekemans M, Gleeson JG, Valente EM, Jackson PK, Drummond IA, Saunier S, Attié-Bitach T. A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. Hum Mutat. 2014 Jan;35(1):137-46.

Hedgehog signaling requires motile cilia in the sea urchin

Authors:
Warner JF, McCarthy AM, Morris RL, McClay DR
Citation:
Mol Biol Evol. 2014 Jan;31(1):18-22. doi: 10.1093/molbev/mst176. Epub 2013 Oct 11
Epub:
Not Epub
Abstract:
A relatively small number of signaling pathways govern the early patterning processes of metazoan development. The...
Delivery Method:
microinjection
Organism or Cell Type:
Lytechinus variegatus (sea urchin)
Citation Extract:
Warner JF, McCarthy AM, Morris RL, McClay DR. Hedgehog signaling requires motile cilia in the sea urchin. Mol Biol Evol. 2014 Jan;31(1):18-22. doi: 10.1093/molbev/mst176. Epub 2013 Oct 11.

Histone titration against the genome sets the DNA-to-cytoplasm threshold for the Xenopus midblastula transition

Authors:
Amodeo AA, Jukam D, Straight AF, Skotheim JM
Citation:
PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1413990112
Epub:
Yes
Abstract:
Embryos depend on maternally deposited RNA until zygotic transcription activates. In many species, genome activation coincides...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Amodeo AA, Jukam D, Straight AF, Skotheim JM. Histone titration against the genome sets the DNA-to-cytoplasm threshold for the Xenopus midblastula transition. PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1413990112.

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