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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia

Authors:
Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, Goi K, Matsubara K, Koike K, Ishiguro A, Okamoto Y, Watanabe K, Kanno H, Kojima S, Miyano S, Kenmochi N, Ogawa S, Ito E
Citation:
Br J Haematol. 2014 Nov 25. doi: 10.1111/bjh.13229. [Epub ahead of print]
Epub:
Yes
Abstract:
Diamond-Blackfan anaemia is a congenital bone marrow failure syndrome that is characterized by red blood cell aplasia. The...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/bjh.13229/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, Goi K, Matsubara K, Koike K, Ishiguro A, Okamoto Y, Watanabe K, Kanno H, Kojima S, Miyano S, Kenmochi N, Ogawa S, Ito E. Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia. Br J Haematol. 2014 Nov 25. doi: 10.1111/bjh.13229. [Epub ahead of print].

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

Authors:
De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guérin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W
Citation:
Cell Death Differ. 2014 Nov 28. doi: 10.1038/cdd.2014.191. [Epub ahead of print]
Epub:
Yes
Abstract:
Receptor-interacting protein kinase 4 (RIPK4)-deficient mice have epidermal defects and fusion of all external orifices. These...
Link:
http://www.nature.com/cdd/journal/vaop/ncurrent/full/cdd2014191a.html
Organism or Cell Type:
Xenopus
Citation Extract:
De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guérin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W. A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes. Cell Death Differ. 2014 Nov 28. doi: 10.1038/cdd.2014.191. [Epub ahead of print].

ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions

Authors:
Chang GH, Lay AJ, Ting KK, Zhao Y, Coleman PR, Powter EE, Formaz-Preston A, Jolly CJ, Bower NI, Hogan BM, Rinkwitz S, Becker TS, Vadas MA, Gamble JR
Citation:
Small GTPases. 2014 Nov 25:0. [Epub ahead of print]
Epub:
Yes
Abstract:
The formation of the vascular network requires a tightly controlled balance of pro-angiogenic and stabilizing signals....
Link:
http://www.tandfonline.com/doi/abs/10.4161/21541248.2014.975002#.VHy3QMkXI6I
Organism or Cell Type:
zebrafish
Citation Extract:
Chang GH, Lay AJ, Ting KK, Zhao Y, Coleman PR, Powter EE, Formaz-Preston A, Jolly CJ, Bower NI, Hogan BM, Rinkwitz S, Becker TS, Vadas MA, Gamble JR. ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions. Small GTPases. 2014 Nov 25:0. [Epub ahead of print].

Pregnane X Receptor and Aryl Hydrocarbon Receptor Both Are Involved in Transcriptional Regulation of pxr, CYP2 and CYP3 Genes in Developing Zebrafish

Authors:
Kubota A, Goldstone JV, Lemaire B, Takata M, Woodin BR, Stegeman JJ
Citation:
Toxicol Sci. 2014 Nov 25. pii: kfu240. [Epub ahead of print]
Epub:
Yes
Abstract:
Ligand-activated receptors regulate numerous genes, and mediate effects of a broad set of endogenous and exogenous chemicals in...
Link:
http://toxsci.oxfordjournals.org/content/early/2014/11/25/toxsci.kfu240.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Kubota A, Goldstone JV, Lemaire B, Takata M, Woodin BR, Stegeman JJ. Pregnane X Receptor and Aryl Hydrocarbon Receptor Both Are Involved in Transcriptional Regulation of pxr, CYP2 and CYP3 Genes in Developing Zebrafish. Toxicol Sci. 2014 Nov 25. pii: kfu240. [Epub ahead of print].

Time Point-based Integrative Analyses of Deep-transcriptome Identify Four Signal Pathways in Blastemal Regeneration of Zebrafish Lower Jaw

Authors:
Zhang H, Wang X, Lv K, Gao S, Wang G, Fan C, Zhang XA, Yan J
Citation:
Stem Cells. 2014 Nov 25. doi: 10.1002/stem.1899. [Epub ahead of print]
Epub:
Yes
Abstract:
There has been growing interest in applying tissue engineering to stem cell-based regeneration therapies. We have previously...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/stem.1899/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang H, Wang X, Lv K, Gao S, Wang G, Fan C, Zhang XA, Yan J. Time Point-based Integrative Analyses of Deep-transcriptome Identify Four Signal Pathways in Blastemal Regeneration of Zebrafish Lower Jaw. Stem Cells. 2014 Nov 25. doi: 10.1002/stem.1899. [Epub ahead of print].

DEPDC1B Coordinates De-adhesion Events and Cell-Cycle Progression at Mitosis

Authors:
Marchesi S, Montani F, Deflorian G, D’Antuono R, Cuomo A, Bologna S, Mazzoccoli C, Bonaldi T, Di Fiore PP, Nicassio F
Citation:
Dev Cell. 2014;31(4):420-33
Epub:
Not Epub
Abstract:
Cells entering mitosis become rounded, lose attachment to the substrate, and increase their cortical rigidity. Pivotal to these...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2814%2900595-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marchesi S, Montani F, Deflorian G, D’Antuono R, Cuomo A, Bologna S, Mazzoccoli C, Bonaldi T, Di Fiore PP, Nicassio F. DEPDC1B Coordinates De-adhesion Events and Cell-Cycle Progression at Mitosis. Dev Cell. 2014;31(4):420-33.

Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion

Authors:
Jones LA, Villemant C, Starborg T, Salter A, Goddard G, Ruane P, Woodman PG, Papalopulu N, Woolner S, Allan VJ
Citation:
J Cell Biol. 2014;207:499-516. doi:10.1083/jcb.201408025
Epub:
Not Epub
Abstract:
Cytoplasmic dynein 1 (dynein) is a minus end-directed microtubule motor protein with many cellular functions, including during...
Link:
http://jcb.rupress.org/content/207/4/499.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jones LA, Villemant C, Starborg T, Salter A, Goddard G, Ruane P, Woodman PG, Papalopulu N, Woolner S, Allan VJ. Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion. J Cell Biol. 2014;207:499-516. doi:10.1083/jcb.201408025.

Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes for Intra-Articular Delivery to Chondrocytes

Authors:
Sacchetti C, Liu Bryan R, Magrini A, Rosato N, Bottini N, Bottini M
Citation:
ACS Nano. 2014 Nov 21. [Epub ahead of print]
Epub:
Yes
Abstract:
Osteoarthritis (OA) is a common and debilitating degenerative disease of articular joints for which no disease-modifying...
Link:
http://pubs.acs.org/doi/abs/10.1021/nn504537b
Delivery Method:
nanotube in culture, nanotube IA injection
Organism or Cell Type:
cell culture: HEK293Y and mice
Citation Extract:
Sacchetti C, Liu Bryan R, Magrini A, Rosato N, Bottini N, Bottini M. Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes for Intra-Articular Delivery to Chondrocytes. ACS Nano. 2014 Nov 21. [Epub ahead of print].

AHR2-mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs

Authors:
Jayasundara N, Van Tiem Garner L, Meyer JN, Erwin K, Di Giulio RT
Citation:
Toxicol Sci. 2014 Nov 19. pii: kfu245. [Epub ahead of print]
Epub:
Yes
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) induce developmental defects including cardiac deformities in fish. The aryl...
Link:
http://toxsci.oxfordjournals.org/content/early/2014/11/19/toxsci.kfu245.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jayasundara N, Van Tiem Garner L, Meyer JN, Erwin K, Di Giulio RT. AHR2-mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs. Toxicol Sci. 2014 Nov 19. pii: kfu245. [Epub ahead of print].

Molecular cloning and functional characterization of chicken Atonal homologue 1: a comparison with human Atoh1

Authors:
Mulvaney JF, Amemiya Y, Freeman SD, Ladher RK, Dabdoub A
Citation:
Biol Cell. 2014 Nov 21. doi: 10.1111/boc.201400078. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND INFORMATION: The vertebrate basic helix-loop-helix transcription factor Atoh1 is essential for maturation and...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/boc.201400078/abstract
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Mulvaney JF, Amemiya Y, Freeman SD, Ladher RK, Dabdoub A. Molecular cloning and functional characterization of chicken Atonal homologue 1: a comparison with human Atoh1. Biol Cell. 2014 Nov 21. doi: 10.1111/boc.201400078. [Epub ahead of print].

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