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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish

Authors:
Paridaen JT, Janson E, Utami KH, Pereboom TC, Essers PB, van Rooijen C, Zivkovic D, MacInnes AW
Citation:
Dev Biol. 2011 Jul 15;355(2):286-301. doi: 10.1016/j.ydbio.2011.04.028. Epub 2011 Apr 30
Epub:
Not Epub
Abstract:
Nucleostemin (NS), a member of a family of nucleolar GTP-binding proteins, is highly expressed in proliferating cells such as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paridaen JT, Janson E, Utami KH, Pereboom TC, Essers PB, van Rooijen C, Zivkovic D, MacInnes AW. The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish. Dev Biol. 2011 Jul 15;355(2):286-301. doi: 10.1016/j.ydbio.2011.04.028. Epub 2011 Apr 30.

The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos

Authors:
Hashimoto H, Enomoto T, Kumano G, Nishida H
Citation:
Development. 2011 Jun;138(12):2591-600. doi: 10.1242/dev.053082. Erratum in: Development. 2011 Jun;138(12). doi: 10.1242/dev.070383. Enomoto, Atsushi [corrected to Enomoto, Takashi]. Development. 2011 Jul;138(14):3091
Epub:
Not Epub
Abstract:
In embryos of the ascidian Halocynthia roretzi, the competence of isolated presumptive notochord blastomeres to respond to...
Delivery Method:
microinjection
Organism or Cell Type:
Halocynthia roretzi
Citation Extract:
Hashimoto H, Enomoto T, Kumano G, Nishida H. The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos. Development. 2011 Jun;138(12):2591-600. doi: 10.1242/dev.053082. Erratum in: Development. 2011 Jun;138(12). doi: 10.1242/dev.070383. Enomoto, Atsushi [corrected to Enomoto, Takashi]. Development. 2011 Jul;138(14):3091.

Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water

Authors:
Kumai Y, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1517-28. doi: 10.1152/ajpregu.00282.2011. Epub 2011 Aug 10
Epub:
Not Epub
Abstract:
The involvement of a Na+/H+ exchanger (NHE) in mediating Na+ uptake by freshwater fish is currently debated. Although supported...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Perry SF. Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water. Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1517-28. doi: 10.1152/ajpregu.00282.2011. Epub 2011 Aug 10.

The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis

Authors:
Rodríguez P, Higueras MA, González-Rajal A, Alfranca A, Fierro-Fernández M, García-Fernández RA, Ruiz-Hidalgo MJ, Monsalve M, Rodríguez-Pascual F, Redondo JM, de la Pompa JL, Laborda J, Lamas S
Citation:
Cardiovasc Res. 2012 Feb 1;93(2):232-41. doi: 10.1093/cvr/cvr296. Epub 2011 Nov 8
Epub:
Not Epub
Abstract:
AIMS: The epidermal growth factor-like protein Delta-like 1 (DLK1) regulates multiple differentiation processes. It resembles...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodríguez P, Higueras MA, González-Rajal A, Alfranca A, Fierro-Fernández M, García-Fernández RA, Ruiz-Hidalgo MJ, Monsalve M, Rodríguez-Pascual F, Redondo JM, de la Pompa JL, Laborda J, Lamas S. The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovasc Res. 2012 Feb 1;93(2):232-41. doi: 10.1093/cvr/cvr296. Epub 2011 Nov 8.

A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization

Authors:
Pereboom TC, van Weele LJ, Bondt A, MacInnes AW
Citation:
Blood. 2011 Nov 17;118(20):5458-65. doi: 10.1182/blood-2011-04-351460. Epub 2011 Sep 14
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is a bone marrow failure disorder characterized by shortened telomeres, defective stem cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pereboom TC, van Weele LJ, Bondt A, MacInnes AW. A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization. Blood. 2011 Nov 17;118(20):5458-65. doi: 10.1182/blood-2011-04-351460. Epub 2011 Sep 14.

Dihydrofolate reductase is required for the development of heart and outflow tract in zebrafish

Authors:
Sun S, Gui Y, Jiang Q, Song H
Citation:
Acta Biochim Biophys Sin (Shanghai). 2011 Dec;43(12):957-69. doi: 10.1093/abbs/gmr098
Epub:
Not Epub
Abstract:
Folic acid is very important for embryonic development and folic acid inhibition can cause congenital heart defects in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun S, Gui Y, Jiang Q, Song H. Dihydrofolate reductase is required for the development of heart and outflow tract in zebrafish. Acta Biochim Biophys Sin (Shanghai). 2011 Dec;43(12):957-69. doi: 10.1093/abbs/gmr098.

Smoc2 modulates embryonic myelopoiesis during zebrafish development

Authors:
Mommaerts H, Esguerra CV, Hartmann U, Luyten FP, Tylzanowski P
Citation:
Dev Dyn. 2014;[Epub ahead of print] doi:10.1002/dvdy.24164
Epub:
Yes
Abstract:
Background: SMOC2 is a member of the BM-40 (SPARC) family of matricellular proteins, reported to influence signaling in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mommaerts H, Esguerra CV, Hartmann U, Luyten FP, Tylzanowski P. Smoc2 modulates embryonic myelopoiesis during zebrafish development. Dev Dyn. 2014;[Epub ahead of print] doi:10.1002/dvdy.24164.

Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy

Authors:
Li J, Qi M, Li C, Shi D, Zhang D, Xie D, Yuan T, Feng J, Liu Y, Liang D, Xu X, Chen J, Xu L, Zhang H, Ye J, Lv F, Huang J, Peng L, Chen YH
Citation:
Cell Res. 2014 Jul 15. doi: 10.1038/cr.2014.94. [Epub ahead of print]
Epub:
Yes
Abstract:
Pathological cardiac hypertrophy is an inevitable forerunner of heart failure. Regardless of the etiology of cardiac...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Qi M, Li C, Shi D, Zhang D, Xie D, Yuan T, Feng J, Liu Y, Liang D, Xu X, Chen J, Xu L, Zhang H, Ye J, Lv F, Huang J, Peng L, Chen YH. Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy. Cell Res. 2014 Jul 15. doi: 10.1038/cr.2014.94. [Epub ahead of print].

Thrombospondin-4 controls matrix assembly during development and Repair of Myotendinous Junctions

Authors:
Subramanian A, Schilling TF
Citation:
Elife. 2014 Jun 18:e02372. doi: 10.7554/eLife.02372. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Tendons are extracellular matrix (ECM)-rich structures that mediate muscle attachments with the skeleton, but surprisingly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramanian A, Schilling TF. Thrombospondin-4 controls matrix assembly during development and Repair of Myotendinous Junctions. Elife. 2014 Jun 18:e02372. doi: 10.7554/eLife.02372. [Epub ahead of print].

TGF-β-activated kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit α (PKACα) and Protein Kinase X (PRKX)

Authors:
Ouyang C, Nie L, Gu M, Wu A, Han X, Wang X, Shao J, Xia Z
Citation:
J Biol Chem. 2014 Aug 29;289(35):24226-37. doi: 10.1074/jbc.M114.559963. Epub 2014 Jul 15.
Epub:
Yes
Abstract:
TGF-β-activated kinase 1 (TAK1) is a key kinase in mediating toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouyang C, Nie L, Gu M, Wu A, Han X, Wang X, Shao J, Xia Z. TGF-β-activated kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit α (PKACα) and Protein Kinase X (PRKX). J Biol Chem. 2014 Aug 29;289(35):24226-37. doi: 10.1074/jbc.M114.559963. Epub 2014 Jul 15..

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