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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO

Authors:
Yin H, Moulton HM, Betts C, Merritt T, Seow Y, Ashraf S, Wang Q, Boutilier J, Wood MJ
Citation:
Mol Ther. 2010 Aug 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Splice modulation using antisense oligonucleotides (AOs) has been shown to yield targeted exon exclusion to restore the open...
Delivery Method:
i.v. injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Moulton HM, Betts C, Merritt T, Seow Y, Ashraf S, Wang Q, Boutilier J, Wood MJ. Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO. Mol Ther. 2010 Aug 10. [Epub ahead of print].

Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult

Authors:
Yeh TC, Chiang PC, Li TK, Hsu JL, Lin CJ, Wang SW, Peng CY, Guh JH
Citation:
Biochem Pharmacol. 2007 Mar 15;73(6):782-92. Epub 2006 Dec 3
Epub:
Not Epub
Abstract:
Hepatocellular carcinoma is a very common malignancy and is chemoresistant to currently available chemotherapeutic agents....
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human hepatocyte Hep3B
Citation Extract:
Yeh TC, Chiang PC, Li TK, Hsu JL, Lin CJ, Wang SW, Peng CY, Guh JH. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. Biochem Pharmacol. 2007 Mar 15;73(6):782-92. Epub 2006 Dec 3.

Gα(13) is closely related to hematopoiesis in zebrafish

Authors:
Ye D, Yang Q, Li Y, Huang X, Hu J, Qian S, Tan Z, Song P
Citation:
Mol Biol Rep. 2010 Nov 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) function as signal transducers and control many...
Organism or Cell Type:
zebrafish
Citation Extract:
Ye D, Yang Q, Li Y, Huang X, Hu J, Qian S, Tan Z, Song P. Gα(13) is closely related to hematopoiesis in zebrafish. Mol Biol Rep. 2010 Nov 27. [Epub ahead of print].

Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish

Authors:
Yin C, Kikuchi K, Hochgreb T, Poss KD, Stainier DY
Citation:
Dev Cell. 2010 Jun 15;18(6):973-84
Epub:
Not Epub
Abstract:
Extracellular matrix (ECM) remodeling is critical for organogenesis, yet its molecular regulation is poorly understood. In...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin C, Kikuchi K, Hochgreb T, Poss KD, Stainier DY. Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. Dev Cell. 2010 Jun 15;18(6):973-84.

HEB and E2A function as SMAD/FOXH1 cofactors

Authors:
Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC
Citation:
Genes Dev. 2011 Aug 1;25(15):1654-61
Epub:
Not Epub
Abstract:
Nodal signaling, mediated through SMAD transcription factors, is necessary for pluripotency maintenance and endoderm commitment...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Yoon SJ, Wills AE, Chuong E, Gupta R, Baker JC. HEB and E2A function as SMAD/FOXH1 cofactors. Genes Dev. 2011 Aug 1;25(15):1654-61.

Hsp90 Selectively Modulates Phenotype in Vertebrate Development

Authors:
Yeyati PL, Bancewicz RM, Maule J, van Heyningen V
Citation:
PLoS Genet. 2007 Mar 30;3(3):e43 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Compromised heat shock protein 90 (Hsp90) function reveals cryptic phenotypes in flies and plants. These observations were...
Organism or Cell Type:
zebrafish
Citation Extract:
Yeyati PL, Bancewicz RM, Maule J, van Heyningen V. Hsp90 Selectively Modulates Phenotype in Vertebrate Development. PLoS Genet. 2007 Mar 30;3(3):e43 [Epub ahead of print].

Human Cytomegalovirus Induces TLR4 Signaling Components in Monocytes Altering TIRAP, TRAM and Downstream Interferon-Beta and TNF-Alpha Expression

Authors:
Yew KH, Carpenter C, Duncan RS, Harrison CJ
Citation:
PLoS ONE. 2012;7(9):e44500. doi:10.1371/journal.pone.0044500
Epub:
Not Epub
Abstract:
Using TLR pathways, primary human cytomegalovirus (HCMV) induces innate responses including the production of inflammatory...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: THP-1 cells
Citation Extract:
Yew KH, Carpenter C, Duncan RS, Harrison CJ. Human Cytomegalovirus Induces TLR4 Signaling Components in Monocytes Altering TIRAP, TRAM and Downstream Interferon-Beta and TNF-Alpha Expression. PLoS ONE. 2012;7(9):e44500. doi:10.1371/journal.pone.0044500.

Identification of CCAAT/Enhancer-binding Proteins as Exchange Protein Activated by cAMP-activated Transcription Factors That Mediate the Induction of the SOCS-3 Gene

Authors:
Yarwood SJ, Borland G, Sands WA, Palmer TM
Citation:
J Biol Chem. 2008 Mar 14;283(11):6843-53. Epub 2008 Jan 14
Epub:
Not Epub
Abstract:
The prototypical second messenger cyclic AMP is a key regulator of immune and inflammatory responses. Its ability to inhibit...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HUVEC
Citation Extract:
Yarwood SJ, Borland G, Sands WA, Palmer TM. Identification of CCAAT/Enhancer-binding Proteins as Exchange Protein Activated by cAMP-activated Transcription Factors That Mediate the Induction of the SOCS-3 Gene. J Biol Chem. 2008 Mar 14;283(11):6843-53. Epub 2008 Jan 14.

Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries

Authors:
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC
Citation:
RNA. 2006 May;12(5):797-806. Epub 2006 Mar 23
Epub:
Not Epub
Abstract:
We have recently described an RNA-only gene regulation system for mammalian cells in which inhibition of self-cleavage of an...
Organism or Cell Type:
cell culture: HEK79
Citation Extract:
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC. Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006 May;12(5):797-806. Epub 2006 Mar 23.

Influence of TCDD on zebrafish CYP1B1 transcription during development

Authors:
Yin HC, Tseng HP, Chung HY, Ko CY, Tzou WS, Buhler DR, Hu CH
Citation:
Toxicol Sci. 2008 May;103(1):158-68. Epub 2008 Feb 27
Epub:
Not Epub
Abstract:
Cytochrome P450 1B1 (CYP1B1) is a heme-containing monooxygenase that metabolizes various polycyclic aromatic hydrocarbons and...
Organism or Cell Type:
zebrafish
Citation Extract:
Yin HC, Tseng HP, Chung HY, Ko CY, Tzou WS, Buhler DR, Hu CH. Influence of TCDD on zebrafish CYP1B1 transcription during development. Toxicol Sci. 2008 May;103(1):158-68. Epub 2008 Feb 27.

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