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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish

Authors:
Wythe JD, Jurynec MJ, Urness LD, Jones CA, Sabeh MK, Werdich AA, Sato M, Yost HJ, Grunwald DJ, Macrae CA, Li DY
Citation:
Dis Model Mech. 2011 May 31. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The vertebrate heart is one of the first organs to form, and its early function and morphogenesis are crucial for continued...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wythe JD, Jurynec MJ, Urness LD, Jones CA, Sabeh MK, Werdich AA, Sato M, Yost HJ, Grunwald DJ, Macrae CA, Li DY. Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Dis Model Mech. 2011 May 31. [Epub ahead of print].

Highly conserved functions of the Brachyury gene on morphogenetic movements: insight from the early-diverging phylum Ctenophora

Authors:
Yamada A, Martindale MQ, Fukui A, Tochinai S
Citation:
Dev Biol. 2009 Dec 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Brachyury, a member of the T-box transcription family identified in a diverse array of metazoans, was initially recognized for...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus and a ctenophore
Citation Extract:
Yamada A, Martindale MQ, Fukui A, Tochinai S. Highly conserved functions of the Brachyury gene on morphogenetic movements: insight from the early-diverging phylum Ctenophora. Dev Biol. 2009 Dec 23. [Epub ahead of print].

Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways

Authors:
Yamaguchi M, Tonou-Fujimori N, Komori A, Maeda R, Nojima Y, Li H, Okamoto H, Masai I
Citation:
Development. 2005 Jul;132(13):3027-43
Epub:
Not Epub
Abstract:
In the developing vertebrate retina, progenitor cells initially proliferate but begin to produce postmitotic neurons when...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yamaguchi M, Tonou-Fujimori N, Komori A, Maeda R, Nojima Y, Li H, Okamoto H, Masai I. Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development. 2005 Jul;132(13):3027-43.

Identification and characterization of ADAM41, a novel ADAM metalloproteinase in Xenopus

Authors:
Xu G, Wei S, White JM, Desimone DW
Citation:
Int J Dev Biol. 2012;56(5):333-9
Epub:
Not Epub
Abstract:
The ADAM family of transmembrane metalloproteinases has important functions in fertilization, development and disease, and is...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Xu G, Wei S, White JM, Desimone DW. Identification and characterization of ADAM41, a novel ADAM metalloproteinase in Xenopus. Int J Dev Biol. 2012;56(5):333-9.

Identification, Characterization, and Effects of Xenopus laevis PNAS-4 Gene on Embryonic Development

Authors:
Yan F, Ruan XZ, Yang SH, Yao SH, Zhao XY, Gou LT, Ma FX, Yuan Z, Deng HX, Wei YQ
Citation:
J Biomed Biotechnol. 2010;2010:134764. Epub 2010 May 4.
Epub:
Not Epub
Abstract:
Apoptosis plays an important role in embryonic development. PNAS-4 has been demonstrated to induce apoptosis in several cancer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yan F, Ruan XZ, Yang SH, Yao SH, Zhao XY, Gou LT, Ma FX, Yuan Z, Deng HX, Wei YQ. Identification, Characterization, and Effects of Xenopus laevis PNAS-4 Gene on Embryonic Development. J Biomed Biotechnol. 2010;2010:134764. Epub 2010 May 4..

Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function

Authors:
Xi Y, Ryan J, Noble S, Yu M, Yilbas AE, Ekker M
Citation:
Eur J Neurosci. 2010 Feb 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in the human PTEN-induced kinase 1 (PINK1) gene are linked to recessive familial Parkinson's disease. Animal...
Organism or Cell Type:
zebrafish
Citation Extract:
Xi Y, Ryan J, Noble S, Yu M, Yilbas AE, Ekker M. Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function. Eur J Neurosci. 2010 Feb 5. [Epub ahead of print].

Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy

Authors:
Yamamoto M, Yang G, Hong C, Liu J, Holle E, Yu X, Wagner T, Vatner SF, Sadoshima J.
Citation:
J Clin Invest. 2003 Nov;112(9):1395-406
Epub:
Not Epub
Abstract:
Thioredoxin 1 (Trx1) has redox-sensitive cysteine residues and acts as an antioxidant in cells. However, the extent of Trx1...
Delivery Method:
Osmotic Delivery System
Organism or Cell Type:
cell culture: rat cardiac myocytes
Citation Extract:
Yamamoto M, Yang G, Hong C, Liu J, Holle E, Yu X, Wagner T, Vatner SF, Sadoshima J.. Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. J Clin Invest. 2003 Nov;112(9):1395-406.

IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos

Authors:
Yamashiro S, Abe H, Mabuchi I
Citation:
Dev Biol. 2007 Jun 9; [Epub ahead of print]
Epub:
Not Epub
Abstract:
We have previously identified two Xenopus homologues of mammalian IQGAP, XIQGAP1 and XIQGAP2, which show high homology with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yamashiro S, Abe H, Mabuchi I. IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos. Dev Biol. 2007 Jun 9; [Epub ahead of print].

Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumor growth in mice

Authors:
Xiang W, Ke Z, Zhang Y, Cheng GH, Irwan ID, Sulochana KN, Potturi P, Wang Z, Yang H, Wang J, Zhuo L, Kini RM, Ge R
Citation:
J Cell Mol Med. 2009 Oct 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Abstract Antiangiogenesis represents a promising therapeutic strategy for the treatment of various malignances. Isthmin is a...
Organism or Cell Type:
zebrafish
Citation Extract:
Xiang W, Ke Z, Zhang Y, Cheng GH, Irwan ID, Sulochana KN, Potturi P, Wang Z, Yang H, Wang J, Zhuo L, Kini RM, Ge R. Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumor growth in mice. J Cell Mol Med. 2009 Oct 29. [Epub ahead of print].

ISWI contributes to ArsI insulator function in development of the sea urchin

Authors:
Yajima M, Fairbrother WG, Wessel GM
Citation:
Development. 2012 Oct;139(19):3613-22. doi: 10.1242/dev.081828
Epub:
Not Epub
Abstract:
Insulators are genomic elements that regulate transcriptional activity by forming chromatin boundaries. Various DNA insulators...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Yajima M, Fairbrother WG, Wessel GM. ISWI contributes to ArsI insulator function in development of the sea urchin. Development. 2012 Oct;139(19):3613-22. doi: 10.1242/dev.081828.

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