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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Fishing the Molecular Bases of Treacher Collins Syndrome

Authors:
Weiner AMJ, Scampoli NL, Calcaterra NB
Citation:
PLoS ONE. 2012;7(1): e29574. doi:10.1371/journal.pone.0029574
Epub:
Not Epub
Abstract:
Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development, and mutations in the TCOF1 gene...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weiner AMJ, Scampoli NL, Calcaterra NB. Fishing the Molecular Bases of Treacher Collins Syndrome. PLoS ONE. 2012;7(1): e29574. doi:10.1371/journal.pone.0029574.

Frizzled-7 signalling controls tissue separation during Xenopus gastrulation

Authors:
Winklbauer R, Medina A, Swain RK, Steinbeisser H
Citation:
Nature. 2001 Oct 25;413(6858):856-60
Epub:
Not Epub
Abstract:
Cell signalling through Frizzled receptors has evolved to considerable complexity within the metazoans. The Frizzled-dependent...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Winklbauer R, Medina A, Swain RK, Steinbeisser H. Frizzled-7 signalling controls tissue separation during Xenopus gastrulation. Nature. 2001 Oct 25;413(6858):856-60.

Frog virus 3 ORF 53R, a putative myristoylated membrane protein, is essential for virus replication in vitro

Authors:
Whitley DS, Yu K, Sample RC, Sinning A, Henegar J, Norcross E, Chinchar VG
Citation:
Virology. 2010 Sep 30;405(2):448-56. doi: 10.1016/j.virol.2010.06.034. Epub 2010 Jul 14. PMID: 20633916
Epub:
Not Epub
Abstract:
Although previous work identified 12 complementation groups with possible roles in virus assembly, currently only one frog...
Link:
https://www.sciencedirect.com/science/article/pii/S0042682210004162
Organism or Cell Type:
Frog virus 3 in cultured cells
Citation Extract:
Whitley DS, Yu K, Sample RC, Sinning A, Henegar J, Norcross E, Chinchar VG. Frog virus 3 ORF 53R, a putative myristoylated membrane protein, is essential for virus replication in vitro. Virology. 2010 Sep 30;405(2):448-56. doi: 10.1016/j.virol.2010.06.034. Epub 2010 Jul 14. PMID: 20633916.

Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis

Authors:
Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT
Citation:
Nature. 2009 Mar 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signalling is essential for several aspects of embryogenesis. In Drosophila, Hh transduction is mediated by a...
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT. Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature. 2009 Mar 22. [Epub ahead of print].

Gene doping: the hype and the reality

Authors:
Wells DJ
Citation:
Br J Pharmacol. 2008 Jun;154(3):623-31. Epub 2008 Apr 21
Epub:
Not Epub
Abstract:
Some spectacular results from genetic manipulation of laboratory rodents and increasing developments in human gene therapy...
Link:
http://onlinelibrary.wiley.com/doi/10.1038/bjp.2008.144/abstract
Delivery Method:
in vivo: injection
Organism or Cell Type:
MDX mice
Citation Extract:
Wells DJ. Gene doping: the hype and the reality. Br J Pharmacol. 2008 Jun;154(3):623-31. Epub 2008 Apr 21.

Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers

Authors:
Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S
Citation:
PLoS Pathog. 2006 Jan;2(1):e1. Epub 2006 Jan 13
Epub:
Not Epub
Abstract:
The filoviruses Marburg virus and Ebola virus (EBOV) quickly outpace host immune responses and cause hemorrhagic fever,...
Link:
http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.0020001
Delivery Method:
Injection, cell bathing
Organism or Cell Type:
Rhesus macaque, mouse, guinea pig, Vero cells
Citation Extract:
Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S. Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers. PLoS Pathog. 2006 Jan;2(1):e1. Epub 2006 Jan 13.

Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis

Authors:
Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S
Citation:
Cell Res. 2008 Jun;18(6):677-85.
Epub:
Not Epub
Abstract:
Growth factor independence 1 (GFI1) is important for maturation of mammalian lymphocytes and neutrophils and maintenance of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S. Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis. Cell Res. 2008 Jun;18(6):677-85..

GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling

Authors:
Willaert A, Khatri S, Callewaert BL, Coucke PJ, Crosby SD, Lee JG, Davis EC, Shiva S, Tsang M, De Paepe A, Urban Z
Citation:
Hum Mol Genet. 2012 Mar 15;21(6):1248-59. Epub 2011 Nov 24.
Epub:
Not Epub
Abstract:
Growth factor signaling results in dramatic phenotypic changes in cells, which require commensurate alterations in cellular...
Organism or Cell Type:
zebrafish
Citation Extract:
Willaert A, Khatri S, Callewaert BL, Coucke PJ, Crosby SD, Lee JG, Davis EC, Shiva S, Tsang M, De Paepe A, Urban Z. GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling. Hum Mol Genet. 2012 Mar 15;21(6):1248-59. Epub 2011 Nov 24..

Gsx transcription factors repress Iroquois gene expression

Authors:
Winterbottom EF, Ramsbottom SA, Isaacs HV
Citation:
Dev Dyn. 2011 Apr 29. doi: 10.1002/dvdy.22648. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We have previously shown that the Gsx family homeobox gene Gsh2 is part of the regulatory network specifying dorsoventral...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Winterbottom EF, Ramsbottom SA, Isaacs HV. Gsx transcription factors repress Iroquois gene expression. Dev Dyn. 2011 Apr 29. doi: 10.1002/dvdy.22648. [Epub ahead of print].

Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta

Authors:
Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R
Citation:
Dev Cell. 2009 Jun;16(6):909-16
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are first detected in the floor of the embryonic dorsal aorta (DA), and we investigate the...
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R. Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta. Dev Cell. 2009 Jun;16(6):909-16.

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