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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Differences in expression pattern and function between zebrafish hoxc13 orthologs: recruitment of Hoxc13b into an early embryonic role

Authors:
Thummel R, Li L, Tanase C, Sarras MP Jr, Godwin AR
Citation:
Dev Biol. 2004 Oct 15;274(2):318-33
Epub:
Not Epub
Abstract:
Vertebrate Hox genes are generally believed to initiate expression at the primitive streak or early neural plate stages. The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thummel R, Li L, Tanase C, Sarras MP Jr, Godwin AR. Differences in expression pattern and function between zebrafish hoxc13 orthologs: recruitment of Hoxc13b into an early embryonic role. Dev Biol. 2004 Oct 15;274(2):318-33.

Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish

Authors:
Tanaka H, Morimura R, Ohshima T
Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.032
Epub:
Not Epub
Abstract:
Dpysl2 (CRMP2) and Dpysl3 (CRMP4) are involved in neuronal polarity and axon elongation in cultured neurons. These proteins are...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka H, Morimura R, Ohshima T. Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.032.

DYX1C1 is required for axonemal dynein assembly and ciliary motility

Authors:
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K; UK10K, Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H
Citation:
Nat Genet. 2013 Jul 21. doi: 10.1038/ng.2707. [Epub ahead of print]
Epub:
Not Epub
Abstract:
DYX1C1 has been associated with dyslexia and neuronal migration in the developing neocortex. Unexpectedly, we found that...
Organism or Cell Type:
zebrafish
Citation Extract:
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K; UK10K, Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Jul 21. doi: 10.1038/ng.2707. [Epub ahead of print].

Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages.

Authors:
Taylor MF, Weller DD, Kobzik L
Citation:
Antisense Nucleic Acid Drug Dev 1998 Jun;8(3):199-205
Epub:
Not Epub
Abstract:
Antisense oligomers can inhibit expression of a single gene in a sequence-specific manner. As a result, these sequences are...
Delivery Method:
lipid-based
Organism or Cell Type:
cell culture: mouse primary alveolar macrophages
Citation Extract:
Taylor MF, Weller DD, Kobzik L. Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages.. Antisense Nucleic Acid Drug Dev 1998 Jun;8(3):199-205.

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells

Authors:
Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC
Citation:
EMBO J. 2012 Oct 3;31(19):3885-900. doi: 10.1038/emboj.2012.246. Epub 2012 Aug 31
Epub:
Not Epub
Abstract:
Both the transforming growth factor β (TGF-β) and integrin signalling pathways have well-established roles in angiogenesis....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC. Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells. EMBO J. 2012 Oct 3;31(19):3885-900. doi: 10.1038/emboj.2012.246. Epub 2012 Aug 31.

Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation.

Authors:
Taneda T, Zhu W, Cao Q, Watanabe H, Yamaguchi Y, Handa H, Wada T
Citation:
Genes Cells 2011 Jan 4. doi: 10.1111/j.1365-2443.2010.01481.x. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent studies have showed that transcription elongation factors regulate early development. Foggy/Spt5 is a subunit of DRB...
Organism or Cell Type:
zebrafish
Citation Extract:
Taneda T, Zhu W, Cao Q, Watanabe H, Yamaguchi Y, Handa H, Wada T. Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation.. Genes Cells 2011 Jan 4. doi: 10.1111/j.1365-2443.2010.01481.x. [Epub ahead of print].

Établissement des axes embryonnaires au cours du développement du poisson zèbre

Authors:
Thisse B, Thisse C
Citation:
MEDECINE/SCIENCES 2002 ; 18 : 193-204
Epub:
Not Epub
Abstract:
La d�finition des axes embryonnaires au cours du d�veloppement du poisson z�bre s'effectue au stade blastula. L...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thisse B, Thisse C. Établissement des axes embryonnaires au cours du développement du poisson zèbre. MEDECINE/SCIENCES 2002 ; 18 : 193-204.

Exon-skipping therapy for Duchenne muscular dystrophy

Authors:
Takeda S
Citation:
Rinsho Shinkeigaku. 2011 Nov;51(11):914-6
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin at the sarcolemma. Exon skipping by antisense...
Delivery Method:
in vivo, injection, i.m. and systemic
Organism or Cell Type:
mouse, mdx52
Citation Extract:
Takeda S. Exon-skipping therapy for Duchenne muscular dystrophy. Rinsho Shinkeigaku. 2011 Nov;51(11):914-6.

Expression of an NK2 homeodomain gene in the apical ectoderm defines a new territory in the early sea urchin embryo

Authors:
Takacs CM, Amore G, Oliveri P, Poustka AJ, Wang D, Burke RD, Peterson KJ
Citation:
Dev Biol. 2004 May 1;269(1):152-64
Epub:
Not Epub
Abstract:
We have identified an NK2 family homeodomain transcription factor, SpNK2.1, in the sea urchin Strongylocentrotus purpuratus...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Takacs CM, Amore G, Oliveri P, Poustka AJ, Wang D, Burke RD, Peterson KJ. Expression of an NK2 homeodomain gene in the apical ectoderm defines a new territory in the early sea urchin embryo. Dev Biol. 2004 May 1;269(1):152-64.

Expression of c-myc is not critical for cell proliferation in established human leukemia lines

Authors:
Tidd DM, Giles RV, Broughton CM, Clark RE
Citation:
BMC Mol Biol. 2001;2(1):13.
Epub:
Not Epub
Abstract:
BACKGROUND: A study was undertaken to resolve preliminary conflicting results on the proliferation of leukemia cells observed...
Delivery Method:
streptolysin O or electroporation
Organism or Cell Type:
cell culture: human leukemia lines
Citation Extract:
Tidd DM, Giles RV, Broughton CM, Clark RE. Expression of c-myc is not critical for cell proliferation in established human leukemia lines. BMC Mol Biol. 2001;2(1):13..

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