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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
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Citation:
Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600 Epub:
Not Epub Abstract:
While neural crest development is known to be transcriptionally controlled via sequential activation of gene regulatory... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME. RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification. Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600. |
Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos
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Citation:
Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print Epub:
Yes Abstract:
Background: Molecular networks associated with dopaminergic (DA) neurogenesis remain undefined within mammalian models. To... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kumar A, Rhee M. Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos. Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print. |
Cyclin B3 implements timely vertebrate oocyte arrest for fertilization
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Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005 Epub:
Not Epub Abstract:
To ensure successful offspring ploidy, vertebrate oocytes must halt the cell cycle in meiosis II until sperm entry. Emi2 is... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Bouftas N, Schneider L, Halder M, Demmig R, Baack M, Cladière D, Walter M, Al Abdallah H, Kleinhempel C, Messaritaki R, Müller J, Passarelli F, Wehrle P, Heim A, Wassmann K, Mayer TU. Cyclin B3 implements timely vertebrate oocyte arrest for fertilization. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005. |
Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells
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Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006 Epub:
Not Epub Abstract:
Yamanaka factors are essential for establishing pluripotency in embryonic stem cells, but their function in multipotent stem... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hovland AS, Bhattacharya D, Azambuja AP, Pramio D, Copeland J, Rothstein M, Simoes-Costa M. Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006. |
Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo
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Citation:
Biochem Biophys Res Commun. 2022 Sep 15;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Online ahead of print Epub:
Not Epub Abstract:
The vertebrate body is organized along the dorsal-ventral (DV) and anterior-posterior (AP) axes by the BMP and Wnt pathways,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Takebayashi-Suzuki K, Uchida M, Suzuki A. Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo. Biochem Biophys Res Commun. 2022 Sep 15;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Online ahead of print. |
Transcription factors interact with RNA to regulate genes
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Citation:
=Mol Cell. 2023 Jul 20;83(14):2449-2463.e13. doi: 10.1016/j.molcel.2023.06.012. Epub 2023 Jul 3. PMID: 37402367; PMCID: PMC10529847 Epub:
Not Epub Abstract:
Transcription factors (TFs) orchestrate the gene expression programs that define each cell's identity. The canonical TF... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oksuz O, Henninger JE, Warneford-Thomson R, Zheng MM, Erb H, Vancura A, Overholt KJ, Hawken SW, Banani SF, Lauman R, Reich LN, Robertson AL, Hannett NM, Lee TI, Zon LI, Bonasio R, Young RA. Transcription factors interact with RNA to regulate genes. =Mol Cell. 2023 Jul 20;83(14):2449-2463.e13. doi: 10.1016/j.molcel.2023.06.012. Epub 2023 Jul 3. PMID: 37402367; PMCID: PMC10529847. |
eIF4B mRNA Translation Contributes to Cleavage Dynamics in Early Sea Urchin Embryos
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Citation:
Biology. 2022;11(10):1408. doi:10.3390/biology11101408 Epub:
Not Epub Abstract:
During the first steps of sea urchin development, fertilization elicits a marked increase in protein synthesis essential for... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus, Sphaerechinus granularis (sea urchins) Citation Extract: Pontheaux F, Boulben S, Chassé H, Boutet A, Roch F, Morales J, Cormier P. eIF4B mRNA Translation Contributes to Cleavage Dynamics in Early Sea Urchin Embryos. Biology. 2022;11(10):1408. doi:10.3390/biology11101408 . |
Ash2l, an obligatory component of H3K4 methylation complexes, regulates neural crest development
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Citation:
Dev Biol. 2022 Sep 23:S0012-1606(22)00179-8. doi: 10.1016/j.ydbio.2022.09.008. Online ahead of print Epub:
Yes Abstract:
The vertebrate nervous system develops from embryonic neural plate and neural crest. Although genetic mechanisms governing... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mohammadparast S, Chang C. Ash2l, an obligatory component of H3K4 methylation complexes, regulates neural crest development. Dev Biol. 2022 Sep 23:S0012-1606(22)00179-8. doi: 10.1016/j.ydbio.2022.09.008. Online ahead of print. |
Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties
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Citation:
Mol Ther Nucleic Acids. 2022 Aug 25;29:955-968. doi: 10.1016/j.omtn.2022.08.033. eCollection 2022 Epub:
Not Epub Abstract:
Therapies that restore dystrophin expression are presumed to correct Duchenne muscular dystrophy (DMD), with antisense-mediated... Delivery Method:
peptide-linked; intravenous (i.v.) Organism or Cell Type:
mdx mice Citation Extract: Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC. Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties. Mol Ther Nucleic Acids. 2022 Aug 25;29:955-968. doi: 10.1016/j.omtn.2022.08.033. eCollection 2022. |
Regulation of Nodal signaling propagation by receptor interactions and positive feedback
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Citation:
Elife. 2022 Sep 23;11:e66397. doi: 10.7554/eLife.66397. Online ahead of print Epub:
Not Epub Abstract:
During vertebrate embryogenesis, the germ layers are patterned by secreted Nodal signals. In the classical model, Nodals elicit... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Preiß H, Kögler AC, Mörsdorf D, Čapek D, Soh GH, Rogers KW, Morales-Navarrete H, Almuedo-Castillo M, Müller P. Regulation of Nodal signaling propagation by receptor interactions and positive feedback. Elife. 2022 Sep 23;11:e66397. doi: 10.7554/eLife.66397. Online ahead of print. |