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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Haploinsufficiency of SF3B2 causes craniofacial microsomia
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Citation:
Nat Commun. 2021;12(1):4680. doi:10.1038/s41467-021-24852-9 Epub:
Not Epub Abstract:
Craniofacial microsomia (CFM) is the second most common congenital facial anomaly, yet its genetic etiology remains unknown. We... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Timberlake AT, Griffin C, Heike Carrie L, Hing AV, Cunningham ML, Chitayat D, Davis MR, Doust SJ, Drake AF, Duenas-Roque MM, Goldblatt J, Gustafson JA, Hurtado-Villa P, Johns A, Karp N, Laing NG, Magee L, Mullegama SV, Pachajoa H, Porras-Hurtado GL, Schnur RE, Slee J, Singer SL, Staffenberg DA, Timms AE, Wise CA, Zarante I, Saint-Jeannet J-P, Luquetti DV. Haploinsufficiency of SF3B2 causes craniofacial microsomia. Nat Commun. 2021;12(1):4680. doi:10.1038/s41467-021-24852-9. |
Crosslinking of CD38 Receptors Triggers Apoptosis of Malignant B Cells
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Citation:
Molecules. 2021;26(15):4658. doi:10.3390/molecules26154658 Epub:
Not Epub Abstract:
Recently, we designed an inventive paradigm in nanomedicine -- drug-free macromolecular therapeutics (DFMT). The ability of... Organism or Cell Type:
cell culture: Raji (Burkitt’s lymphoma), Daudi (Burkitt’s lymphoma), RPMI 8226 (multiple myeloma), and ANBL-6 (multiple myeloma) Citation Extract: Gambles MT, Li J, Wang J, Sborov D, Yang J, Kopeček J. Crosslinking of CD38 Receptors Triggers Apoptosis of Malignant B Cells. Molecules. 2021;26(15):4658. doi:10.3390/molecules26154658. |
Fli1+ cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis
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Citation:
Proc Nat Acad Sci USA. 2021;118(31):e2008559118 Epub:
Yes Abstract:
A network of molecular factors drives the development, differentiation, and maintenance of endothelial cells. Friend leukemia... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Matrone G, Xia B, Chen K, Denvir MA, Andrew H. Baker AH, Cooke JP. Fli1+ cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis. Proc Nat Acad Sci USA. 2021;118(31):e2008559118. |
m(6)A writer complex promotes timely differentiation and survival of retinal progenitor cells in zebrafish
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Citation:
Biochem Biophys Res Commun. 2021 Aug 27;567:171-176. doi: 10.1016/j.bbrc.2021.06.043. Epub 2021 Jun 21 Epub:
Not Epub Abstract:
N6-Methyladenosine (m6A) is the most prevalent internal modification in eukaryotic mRNAs that modulates mRNA metabolism and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang L, Liang H, Wang S, Chen S. m(6)A writer complex promotes timely differentiation and survival of retinal progenitor cells in zebrafish. Biochem Biophys Res Commun. 2021 Aug 27;567:171-176. doi: 10.1016/j.bbrc.2021.06.043. Epub 2021 Jun 21. |
Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells
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Citation:
J Virol. 2021 Sep 27;95(20):e0090621. doi: 10.1128/JVI.00906-21. Epub 2021 Jul 28. PMID: 34319155; PMCID: PMC8475512 Epub:
Not Epub Abstract:
Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: human and mouse airway cells Citation Extract: Bestle D, Limburg H, Kruhl D, Harbig A, Stein DA, Moulton H, Matrosovich M, Abdelwhab EM, Stech J, Böttcher-Friebertshäuser E. Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells. J Virol. 2021 Sep 27;95(20):e0090621. doi: 10.1128/JVI.00906-21. Epub 2021 Jul 28. PMID: 34319155; PMCID: PMC8475512. |
Role of the cardiovascular system in ammonia excretion in early life stages of zebrafish (Danio rerio)
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Citation:
Am J Physiol Regul Integr Comp Physiol. 2021 Jul 28. doi: 10.1152/ajpregu.00284.2020. Online ahead of print Epub:
Yes Abstract:
The purpose of this study was to investigate if the cardiovascular system is important for ammonia excretion in the early life... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Pasparakis C, Grosell M. Role of the cardiovascular system in ammonia excretion in early life stages of zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2021 Jul 28. doi: 10.1152/ajpregu.00284.2020. Online ahead of print. |
Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target
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Citation:
Sci Rep. 2021 Jul 27;11(1):15238. doi: 10.1038/s41598-021-94715-2 Epub:
Not Epub Abstract:
Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade... Delivery Method:
Vivo-Morpholino piggyback hybrid Organism or Cell Type:
zebrafish Citation Extract: Raman R, Fallatah W, Al Qaryoute A, Dhinoja S, Jagadeeswaran P. Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target. Sci Rep. 2021 Jul 27;11(1):15238. doi: 10.1038/s41598-021-94715-2. |
A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress
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Citation:
Nat Commun. 2021;12(1):4484. doi:10.1038/s41467-021-24831-0 Epub:
Not Epub Abstract:
Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cacialli P, Mahony CB, Petzold T, Bordignon P, Rougemont A-L, Bertrand JY. A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress. Nat Commun. 2021;12(1):4484. doi:10.1038/s41467-021-24831-0. |
An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier
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Citation:
Proc Nat Acad Sci USA. 2021;118(30):e2101378118. doi:10.1073/pnas.2101378118 Epub:
Not Epub Abstract:
Otopetrins comprise a family of proton-selective channels that are critically important for the mineralization of otoliths and... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Chang WW, Matt A-S, Schewe M, Musinszki M, Grüssel S, Brandenburg J, Garfield D, Bleich M, Baukrowitz T, Hu MY. An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier. Proc Nat Acad Sci USA. 2021;118(30):e2101378118. doi:10.1073/pnas.2101378118. |
MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes
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Citation:
Nat Commun. 2021;12:4427. doi:10.1038/s41467-021-24724-2 Epub:
Not Epub Abstract:
The membrane-associated RING-CH (MARCH) proteins are E3 ligases that regulate the stability of various cellular membrane... Delivery Method:
intranasal Vivo-Morpholino Organism or Cell Type:
C57Bl/6 mice Citation Extract: Liu X, Xu F, Ren L, Zhao F, Huang Y, Wei L, Wang Y, Wang C, Fan Z, Mei S, Song J, Zhao Z, Cen S, Liang C, Wang J, Guo F. MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes. Nat Commun. 2021;12:4427. doi:10.1038/s41467-021-24724-2. |