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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Loss of CENPF leads to developmental failure in mouse embryos
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Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173 Epub:
Yes Abstract:
Aneuploidy caused by abnormal chromosome segregation during early embryo development leads to embryonic death or congenital... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte, embryo Citation Extract: Zhou C-J, Wang X-Y, Han Z, Wang D-H, Ma Y-Z, Liang C-G. Loss of CENPF leads to developmental failure in mouse embryos. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173. |
Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice
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Citation:
J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) targeting pathologic RNAs have shown promising therapeutic corrections for many genetic... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: patient-derived muscle DM1 mice Citation Extract: Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJA. Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice. J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205. |
Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis
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Citation:
PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698 Epub:
Not Epub Abstract:
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698. |
ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients
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Citation:
Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print] Epub:
Yes Abstract:
Hematopoiesis is a finely regulated process in vertebrates under both homeostatic and stress conditions. By whole exome... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xie Y, Gao L, Xu C, Chu L, Gao L, Wu R, Liu Y, Liu T, Sun XJ, Ren R, Tang J, Zheng Y, Zhou Y, Shen S. ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients. Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print]. |
Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750752 Epub:
Not Epub Abstract:
Classical cadherins are well-known primary adhesion molecules responsible for physically connecting neighboring cells and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1. bioRxiv. 2019;[preprint] doi:10.1101/750752. |
Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750349 Epub:
Not Epub Abstract:
The transport and Golgi organization 1 (TANGO1) family proteins have been shown to play pivotal roles in the secretory pathway... Delivery Method:
FuGENE HD transfection reagent Organism or Cell Type:
cell culture: HeLa Citation Extract: Lekszas C, Foresti O, Raote I, Daniel Lietdke D, Koenig E-M, Nanda I, Vona C, De Coster P, Cauwels R, Malhotra V, Haaf T. Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion. bioRxiv. 2019;[preprint] doi:10.1101/750349. |
Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome
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Citation:
Int J Exp Pathol. 2019 Aug 28. doi: 10.1111/iep.12331. [Epub ahead of print] Epub:
Yes Abstract:
CHARGE syndrome is a congenital disorder with multiple malformations in the craniofacial structures, and cardiovascular and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu ZZ, Guo J, Lu Y, Liu W, Fu X, Yao T, Zhou Y, Xu HA. Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome. Int J Exp Pathol. 2019 Aug 28. doi: 10.1111/iep.12331. [Epub ahead of print]. |
Genetic compensation by epob in pronephros development in epoa mutant zebrafish
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Citation:
Cell Cycle. 2019 Aug 26:1-14. doi: 10.1080/15384101.2019.1656019. [Epub ahead of print] Epub:
Not Epub Abstract:
Zebrafish erythropoietin a (epoa) is a well characterized regulator of red blood cell formation. Recent morpholino mediated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: She J, Wu Y, Lou B, Lodd E, Klems A, Schmoehl F, Yuan Z, Noble FL, Kroll J. Genetic compensation by epob in pronephros development in epoa mutant zebrafish. Cell Cycle. 2019 Aug 26:1-14. doi: 10.1080/15384101.2019.1656019. [Epub ahead of print]. |
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/748970 Epub:
Not Epub Abstract:
It was recently suggested that supplying the brain with new neurons could counteract Alzheimer's disease. This provocative... Delivery Method:
i.c.v. intracerebroventricular injection Organism or Cell Type:
zebrafish Citation Extract: Bhattarai P, Cosacak MI, Mashkaryan V, Yilmaz S, Popova S, Govindarajan N, Brandt K, Zhang Y, Kizil C. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain. bioRxiv. 2019:[preprint] doi:10.1101/748970 . |
Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi
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Citation:
Malar J. 2019;18:294. doi:10.1186/s12936-019-2925-5 Epub:
Not Epub Abstract:
Background: Insecticides are still at the core of insect pest and vector control programmes. Several lines of evidence indicate... Delivery Method:
Vivo-Morpholino bathing Organism or Cell Type:
Anopheles stephensi (mosquito) Citation Extract: Negri A, Ferrari M, Nodari R, Coppa E, Mastrantonio V, Zanzani S, Porretta D, Bandi C, Urbanelli S, Epis S. Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi. Malar J. 2019;18:294. doi:10.1186/s12936-019-2925-5. |