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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Genome-wide identification of binding sites and gene targets of Alx1, a pivotal regulator of echinoderm skeletogenesis

Authors:
Khor JM, Guerrero-Santoro J, Ettensohn CA
Citation:
Development. 2019;146:dev180653. doi: 10.1242/dev.180653
Epub:
Not Epub
Abstract:
Alx1 is a conserved regulator of skeletogenesis in echinoderms and evolutionary changes in Alx1 sequence and expression have...
Link:
https://dev.biologists.org/content/146/16/dev180653
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Khor JM, Guerrero-Santoro J, Ettensohn CA. Genome-wide identification of binding sites and gene targets of Alx1, a pivotal regulator of echinoderm skeletogenesis. Development. 2019;146:dev180653. doi: 10.1242/dev.180653.

Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins

Authors:
Poon J, Fries A, Wessel GM, Yajima M
Citation:
Nat Comm. 2019;10(1):3779. doi:10.1038/s41467-019-11560-8
Epub:
Not Epub
Abstract:
Evolution is proposed to result, in part, from acquisition of new developmental programs. One such example is the appearance of...
Link:
https://www.nature.com/articles/s41467-019-11560-8
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Poon J, Fries A, Wessel GM, Yajima M. Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins. Nat Comm. 2019;10(1):3779. doi:10.1038/s41467-019-11560-8.

Rab35 controls cilium length, function and membrane composition

Authors:
Kuhns S, Seixas C, Pestana S, Tavares B, Nogueira R, Jacinto R, Ramalho JS, Simpson JC, Andersen JS, Echard A, Lopes SS, Barral DC, Blacque OE
Citation:
EMBO Rep. 2019 Aug 21:e47625. doi: 10.15252/embr.201847625. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rab and Arl guanine nucleotide-binding (G) proteins regulate trafficking pathways essential for the formation, function and...
Link:
https://www.embopress.org/doi/full/10.15252/embr.201847625
Organism or Cell Type:
zebrafish
Citation Extract:
Kuhns S, Seixas C, Pestana S, Tavares B, Nogueira R, Jacinto R, Ramalho JS, Simpson JC, Andersen JS, Echard A, Lopes SS, Barral DC, Blacque OE. Rab35 controls cilium length, function and membrane composition. EMBO Rep. 2019 Aug 21:e47625. doi: 10.15252/embr.201847625. [Epub ahead of print].

Sulfatases, in Particular Sulf1, Are Important for the Integrity of the Glomerular Filtration Barrier in Zebrafish

Authors:
Schenk H, Masseli A, Schroder P, Bolaños-Palmieri P, Beese M, Hegermann J, Bräsen JH, Haller H
Citation:
Biomed Res Int. 2019 Jul 22;2019:4508048. doi: 10.1155/2019/4508048. eCollection 2019
Epub:
Not Epub
Abstract:
The 6-O-endosulfatases (sulfs) are important enzymatic components involved in the regulation of heparan sulfate by altering the...
Link:
https://www.hindawi.com/journals/bmri/2019/4508048/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schenk H, Masseli A, Schroder P, Bolaños-Palmieri P, Beese M, Hegermann J, Bräsen JH, Haller H. Sulfatases, in Particular Sulf1, Are Important for the Integrity of the Glomerular Filtration Barrier in Zebrafish. Biomed Res Int. 2019 Jul 22;2019:4508048. doi: 10.1155/2019/4508048. eCollection 2019.

Nicastrin Deficiency Induces Tyrosinase-dependent Depigmentation and Skin Inflammation

Authors:
Hsu C-h, Liou G-G, Jiang Y-J
Citation:
J Invest Dermatol. 2019;[Epub ahead of print] doi:10.1016/j.jid.2019.07.702
Epub:
Not Epub
Abstract:
Skin depigmentation diseases, such as vitiligo, are pigmentation disorders that often destroy melanocytes. However, their...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0022202X19327009
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu C-h, Liou G-G, Jiang Y-J. Nicastrin Deficiency Induces Tyrosinase-dependent Depigmentation and Skin Inflammation. J Invest Dermatol. 2019;[Epub ahead of print] doi:10.1016/j.jid.2019.07.702.

Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

Authors:
Costa R, Peruzzo R, Bachmann M, Montà GD, Vicario M, Santinon G, Mattarei A, Moro E, Quintana-Cabrera R, Scorrano L, Zeviani M, Vallese F, Zoratti M, Paradisi C, Argenton F, Brini M, Calì T, Dupont S, Szabò I, Leanza L
Citation:
Cell Rep. 2019;28(8)1949-60. doi:10.1016/j.celrep.2019.07.050
Epub:
Not Epub
Abstract:
Wnt signaling affects fundamental development pathways and, if aberrantly activated, promotes the development of cancers. Wnt...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30954-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Costa R, Peruzzo R, Bachmann M, Montà GD, Vicario M, Santinon G, Mattarei A, Moro E, Quintana-Cabrera R, Scorrano L, Zeviani M, Vallese F, Zoratti M, Paradisi C, Argenton F, Brini M, Calì T, Dupont S, Szabò I, Leanza L. Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction. Cell Rep. 2019;28(8)1949-60. doi:10.1016/j.celrep.2019.07.050.

Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia

Authors:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C
Citation:
J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201901077
Epub:
Yes
Abstract:
Correct nuclear position is crucial for cellular function and tissue development. Depending on cell context, however, the...
Link:
http://jcb.rupress.org/content/early/2019/08/14/jcb.201901077
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C. Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia. J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201901077 .

The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration

Authors:
Kara N, Kent MR, Didiano D, Rajaram K, Zhao A, Summerbell ER, Patton JG
Citation:
Cell Rep. 2019;28(8):2037-47. doi:10.1016/j.celrep.2019.07.061
Epub:
Not Epub
Abstract:
Unlike the adult mammalian retina, Müller glia (MG) in the adult zebrafish retina are able to dedifferentiate into a “stem cell...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30965-9
Delivery Method:
ocular injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Kara N, Kent MR, Didiano D, Rajaram K, Zhao A, Summerbell ER, Patton JG. The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration. Cell Rep. 2019;28(8):2037-47. doi:10.1016/j.celrep.2019.07.061.

Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy

Authors:
van Karnebeek CDM, Ramos RJ, Wen X-Y, Tarailo-Graovac M, Gleeson JG, Skrypnyk C, Brand-Arzamendi K, Karbassi F, Issa MY, van der Lee R, Drögemöller BI, Koster J, Rousseau J, Campeau PM, Wang Y, Cao F, Li M, Ruiter J, Ciapaite J, Kluijtmans LAJ, Willemsen MAAP, Jans JJ, Ross CJ, Wintjes LT, Rodenburg YJ, Huigen MCDG, Jia Z, Waterham ER, Wasserman WW, Wanders RJA, Verhoeven-Duif NM, Zaki MS, Wevers RA
Citation:
Am J Hum Genet. 2019;[Epub ahead of print] 10.1016/j.ajhg.2019.07.015
Epub:
Yes
Abstract:
Early-infantile encephalopathies with epilepsy are devastating conditions mandating an accurate diagnosis to guide proper...
Link:
https://www.cell.com/ajhg/pdfExtended/S0002-9297(19)30278-2
Organism or Cell Type:
zebrafish
Citation Extract:
van Karnebeek CDM, Ramos RJ, Wen X-Y, Tarailo-Graovac M, Gleeson JG, Skrypnyk C, Brand-Arzamendi K, Karbassi F, Issa MY, van der Lee R, Drögemöller BI, Koster J, Rousseau J, Campeau PM, Wang Y, Cao F, Li M, Ruiter J, Ciapaite J, Kluijtmans LAJ, Willemsen MAAP, Jans JJ, Ross CJ, Wintjes LT, Rodenburg YJ, Huigen MCDG, Jia Z, Waterham ER, Wasserman WW, Wanders RJA, Verhoeven-Duif NM, Zaki MS, Wevers RA. Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy. Am J Hum Genet. 2019;[Epub ahead of print] 10.1016/j.ajhg.2019.07.015 .

Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential

Authors:
Swartz SZ, McKay LS, Su K-C, Padeganeh A, Paul S. Maddox PS, Knouse KA, Cheeseman IM.
Citation:
Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.07.016
Epub:
Yes
Abstract:
Centromeres provide a robust model for epigenetic inheritance as they are specified by sequence-independent mechanisms...
Link:
https://www.cell.com/developmental-cell/fulltext/S1534-5807(19)30622-7
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (starfish)
Citation Extract:
Swartz SZ, McKay LS, Su K-C, Padeganeh A, Paul S. Maddox PS, Knouse KA, Cheeseman IM.. Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential. Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.07.016.

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