You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

Moderate Elevation of Homocysteine Induces Endothelial Dysfunction through Adaptive UPR Activation and Metabolic Rewiring

Authors:
Chatterje B, Fatima F, Seth S, Sinha Roy S
Citation:
Cells. 2024;13:214. doi:10.3390/cells13030214
Epub:
Not Epub
Abstract:
Elevation of the intermediate amino acid metabolite Homocysteine (Hcy) causes Hyperhomocysteinemia (HHcy), a metabolic disorder...
Link:
https://www.mdpi.com/2073-4409/13/3/214
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chatterje B, Fatima F, Seth S, Sinha Roy S. Moderate Elevation of Homocysteine Induces Endothelial Dysfunction through Adaptive UPR Activation and Metabolic Rewiring. Cells. 2024;13:214. doi:10.3390/cells13030214.

TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish

Authors:
Van Schoor E, Strubbe D, Braems E, Weishaupt J, Ludolph A, Van Damme P, Thal DR, Bercier V, Van Den Bosch L
Citation:
Front Cell Neurosci. 2024;18:[Epub] doi:10.3389/fncel.2024.1340240
Epub:
Yes
Abstract:
Disease-associated variants of TUBA4A (alpha-tubulin 4A) have recently been identified in familial ALS. Interestingly, a...
Link:
https://www.frontiersin.org/articles/10.3389/fncel.2024.1340240/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Schoor E, Strubbe D, Braems E, Weishaupt J, Ludolph A, Van Damme P, Thal DR, Bercier V, Van Den Bosch L. TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish. Front Cell Neurosci. 2024;18:[Epub] doi:10.3389/fncel.2024.1340240.

Deficiency of copper responsive gene stmn4 induces retinal developmental defects

Authors:
Jing Y, Luo Y, Li L, Liu M, Liu JX
Citation:
Cell Biol Toxicol. 2024 Jan 22;40(1):2. doi: 10.1007/s10565-024-09847-8
Epub:
Not Epub
Abstract:
As part of the central nervous system (CNS), the retina senses light and also conducts and processes visual impulses. The...
Link:
https://link.springer.com/article/10.1007/s10565-024-09847-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jing Y, Luo Y, Li L, Liu M, Liu JX. Deficiency of copper responsive gene stmn4 induces retinal developmental defects. Cell Biol Toxicol. 2024 Jan 22;40(1):2. doi: 10.1007/s10565-024-09847-8.

The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio

Authors:
Partevian SA, Safina DR, Rudenok MM, Rybolovlev IN, Semenova EI, Shadrina MI, Slominsky PA, Kostrov SV, Alieva AKh
Citation:
Mol Gen Microbiol Virol. 2024;38:143-9. doi:10.3103/S0891416823030059
Epub:
Not Epub
Abstract:
The Annexin 2 protein (ANXA2) encoded by the ANXA2 gene performs a number of biological functions that are primarily related to...
Link:
https://link.springer.com/article/10.3103/S0891416823030059
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Partevian SA, Safina DR, Rudenok MM, Rybolovlev IN, Semenova EI, Shadrina MI, Slominsky PA, Kostrov SV, Alieva AKh. The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio. Mol Gen Microbiol Virol. 2024;38:143-9. doi:10.3103/S0891416823030059.

Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production

Authors:
Li Y, Li X, Ye D, Zhang R, Liu C, He M, Wang H, Hu W, Sun Y
Citation:
Zool Res. 2024 Jan 18;45(1):176-188. doi: 10.24272/j.issn.2095-8137.2023.032
Epub:
Not Epub
Abstract:
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly docosahexaenoic acid (22:6n-3, DHA), play crucial roles in the...
Link:
https://www.zoores.ac.cn/article/doi/10.24272/j.issn.2095-8137.2023.032
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Li X, Ye D, Zhang R, Liu C, He M, Wang H, Hu W, Sun Y. Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production. Zool Res. 2024 Jan 18;45(1):176-188. doi: 10.24272/j.issn.2095-8137.2023.032.

Ciliary length regulation by intraflagellar transport in zebrafish

Authors:
Sun Y, Chen Z, Jin M, Xie H, Zhao C
Citation:
Elife. 2024 Dec 13;13:RP93168. doi: 10.7554/eLife.93168. PMID: 39671305; PMCID: PMC11643619
Epub:
Not Epub
Abstract:
How cells regulate the size of their organelles remains a fundamental question in cell biology. Cilia, with their simple...
Link:
https://elifesciences.org/articles/93168
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Chen Z, Jin M, Xie H, Zhao C. Ciliary length regulation by intraflagellar transport in zebrafish. Elife. 2024 Dec 13;13:RP93168. doi: 10.7554/eLife.93168. PMID: 39671305; PMCID: PMC11643619.

Dyrk1a is required for craniofacial development in Xenopus laevis

Authors:
Johnson HK, Wahl SE, Sesay F, Litovchick L, Dickinson AJ
Citation:
Dev Biol. 2024 Jul;511:63-75. doi: 10.1016/j.ydbio.2024.04.004. Epub 2024 Apr 15. PMID: 38621649
Epub:
Not Epub
Abstract:
Loss of function mutations in the dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) gene are associated...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S001216062400099X
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Johnson HK, Wahl SE, Sesay F, Litovchick L, Dickinson AJ. Dyrk1a is required for craniofacial development in Xenopus laevis. Dev Biol. 2024 Jul;511:63-75. doi: 10.1016/j.ydbio.2024.04.004. Epub 2024 Apr 15. PMID: 38621649.

Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts

Authors:
Arslan FN, Hannezo É, Merrin J, Loose M, Heisenberg CP
Citation:
Curr Biol. 2024 Jan 8;34(1):171-182.e8. doi: 10.1016/j.cub.2023.11.067. Epub 2023 Dec 21
Epub:
Not Epub
Abstract:
Metazoan development relies on the formation and remodeling of cell-cell contacts. Dynamic reorganization of adhesion receptors...
Link:
https://www.sciencedirect.com/science/article/pii/S096098222301655X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arslan FN, Hannezo É, Merrin J, Loose M, Heisenberg CP. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. Curr Biol. 2024 Jan 8;34(1):171-182.e8. doi: 10.1016/j.cub.2023.11.067. Epub 2023 Dec 21.

amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway

Authors:
Sun L, Ping L, Fan X, Fan Y, Zhang B, Chen X
Citation:
Int J Mol Sci. 2024;25(2):734. doi:10.3390/ijms25020734
Epub:
Not Epub
Abstract:
Microtia-atresia is a rare type of congenital craniofacial malformation causing severe damage to the appearance and hearing...
Link:
https://www.mdpi.com/1422-0067/25/2/734
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun L, Ping L, Fan X, Fan Y, Zhang B, Chen X. amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway. Int J Mol Sci. 2024;25(2):734. doi:10.3390/ijms25020734.

Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation

Authors:
Gerard A, Potocki L, Rosenfeld JA, Lalani SR, Scott TM, Scott D, Azamian MS, Louie R, Moore HW, Champaigne NL, Hollingsworth G, Torella A, Nigro V, Ploski R, Salpietro V, Zara F, Pizzi S, Chillemi G, Ognibene M, Cooney E, Do J, Linnemann A, Larsen MJ, Specht S, Walters KJ, Choi HJ, Choi M, Tartaglia M, Youkharibache P, Chae JH, Capra V, Park SG, Westlake CJ
Citation:
Nat Commun. 2024 Jan 8;15(1):365. doi: 10.1038/s41467-023-44611-2
Epub:
Not Epub
Abstract:
Accogli A, Shakya S, Yang T, Insinna C, Kim SY, Bell D, Butov KR, Severino M, Niceta M, Scala M, Lee HS, Yoo T, Stauffer J,...
Link:
https://www.nature.com/articles/s41467-023-44611-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gerard A, Potocki L, Rosenfeld JA, Lalani SR, Scott TM, Scott D, Azamian MS, Louie R, Moore HW, Champaigne NL, Hollingsworth G, Torella A, Nigro V, Ploski R, Salpietro V, Zara F, Pizzi S, Chillemi G, Ognibene M, Cooney E, Do J, Linnemann A, Larsen MJ, Specht S, Walters KJ, Choi HJ, Choi M, Tartaglia M, Youkharibache P, Chae JH, Capra V, Park SG, Westlake CJ. Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation. Nat Commun. 2024 Jan 8;15(1):365. doi: 10.1038/s41467-023-44611-2.

Pages