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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Combined RhoA Morpholino and ChABC Treatment Protects Identified Lamprey Neurons from Retrograde Apoptosis after Spinal Cord Injury
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Citation:
Front Cell Neurosci. 2023;17:[Epub] doi:10.3389/fncel.2023.1292012 Epub:
Not Epub Abstract:
Previously, we reported that RhoA knockdown by morpholino antisense oligonucleotides (MOs), and enzymatic digestion of... Delivery Method:
Gelfoam at lesion Organism or Cell Type:
lamprey Citation Extract: Hu J, Zhang KG, Rodemer W, Jin L-Q, Selzer ME. Combined RhoA Morpholino and ChABC Treatment Protects Identified Lamprey Neurons from Retrograde Apoptosis after Spinal Cord Injury. Front Cell Neurosci. 2023;17:[Epub] doi:10.3389/fncel.2023.1292012. |
Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer
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Citation:
Drug Deliv Transl Res. 2024 May;14(5):1352-1369. doi: 10.1007/s13346-023-01469-7. Epub 2023 Nov 17. PMID: 37978163; PMCID: PMC10984892. Epub:
Not Epub Abstract:
Antisense oligonucleotide (ASO) is a novel therapeutic platform for targeted cancer therapy. Previously, we have demonstrated... Delivery Method:
CP05 peptide-linked, exosome Organism or Cell Type:
SW620 cells; xenograft mice: athymic BALB/c nude, C57BL/6N, C57BL/6 Citation Extract: Yu S, Liao R, Bai L, Guo M, Zhang Y, Zhang Y, Yang Q, Song Y, Li Z, Meng Q, Wang S, Huang X
. Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer. Drug Deliv Transl Res. 2024 May;14(5):1352-1369. doi: 10.1007/s13346-023-01469-7. Epub 2023 Nov 17. PMID: 37978163; PMCID: PMC10984892.. |
Electrical impedance myography detects dystrophin-related muscle changes in mdx mice
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Citation:
Skelet Muscle. 2023 Nov 18;13(1):19. doi: 10.1186/s13395-023-00331-1 Epub:
Not Epub Abstract:
Background: The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) causes chronic skeletal muscle... Delivery Method:
Pip9b2 peptide-linked; intravenous (i.v.) Organism or Cell Type:
mdx mice Citation Extract: Hiyoshi T, Zhao F, Baba R, Hirakawa T, Kuboki R, Suzuki K, Tomimatsu Y, O'Donnell P, Han S, Zach N, Nakashima M. Electrical impedance myography detects dystrophin-related muscle changes in mdx mice. Skelet Muscle. 2023 Nov 18;13(1):19. doi: 10.1186/s13395-023-00331-1. |
Fold-and-fuse neurulation in zebrafish requires vangl2
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Citation:
Dev Biol. 2025 Aug;524:55-68. doi: 10.1016/j.ydbio.2025.05.001. Epub 2025 May 5. PMID: 40334836 Epub:
Not Epub Abstract:
Shaping of the future brain and spinal cord during neurulation is an essential component of early vertebrate development. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: MacGowan J, Cardenas M, Williams MK. Fold-and-fuse neurulation in zebrafish requires vangl2. Dev Biol. 2025 Aug;524:55-68. doi: 10.1016/j.ydbio.2025.05.001. Epub 2025 May 5. PMID: 40334836. |
Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation
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Citation:
Cell Rep. 2025 Jan 28;44(1):115148. doi: 10.1016/j.celrep.2024.115148. Epub 2024 Dec 31. PMID: 39932187; PMCID: PMC11892348 Epub:
Not Epub Abstract:
Zygotic genome activation (ZGA) initiates transcription in early embryogenesis and requires extensive chromatin remodeling,... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhang J, Li X, Zhao Q, Ji J, Cui H, Hou W, Wang X, Song E, Xiao S, Ling S, Gao S, Liu X, Wen D, Kong Q. Acetylation at lysine 27 on maternal H3.3 regulates minor zygotic genome activation. Cell Rep. 2025 Jan 28;44(1):115148. doi: 10.1016/j.celrep.2024.115148. Epub 2024 Dec 31. PMID: 39932187; PMCID: PMC11892348. |
IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A
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Citation:
Cell Commun Signal. 2023 Nov 9;21(1):322. doi: 10.1186/s12964-023-01349-0 Epub:
Not Epub Abstract:
The unfolded protein response is a survival signaling pathway that is induced during various types of ER stress. Here, we... Organism or Cell Type:
cell culture: 16HBE140 Citation Extract: Gebert M, Bartoszewska S, Opalinski L, Collawn JF, Bartoszewski R. IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A. Cell Commun Signal. 2023 Nov 9;21(1):322. doi: 10.1186/s12964-023-01349-0. |
Optimization and Safety Results of E1v1.11: a morpholino antisense oligonucleotide therapeutic for Spinal Muscular Atrophy
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Citation:
MDA Conference Abstracts. 2024;Poster 85 Epub:
Not Epub Abstract:
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder that is the leading genetic cause of infantile death,... Citation Extract: Oconnor S, Hansen H, Osman E, Kaifer KD, Morcos P, Kacher M, Beatty D, Lorson C. Optimization and Safety Results of E1v1.11: a morpholino antisense oligonucleotide therapeutic for Spinal Muscular Atrophy. MDA Conference Abstracts. 2024;Poster 85. |
Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration
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Citation:
Nat Commun. 2023 Nov 7;14(1):7167. doi: 10.1038/s41467-023-42929-5 Epub:
Not Epub Abstract:
Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Liu C, Liu X, He Z, Zhang J, Tan X, Yang W, Zhang Y, Yu T, Liao S, Dai L, Xu Z, Li F, Huang Y, Zhao J. Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration. Nat Commun. 2023 Nov 7;14(1):7167. doi: 10.1038/s41467-023-42929-5. |
Abstract 14239: Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve
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Citation:
Circulation. 2023;148(Supp 1):A14239 Epub:
Not Epub Abstract:
Background: Extracellular matrix (ECM) is involved in aortic valve development and aortic valve anomaly. ADAMTS gene mediated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin Y, Yang Q, Lin X, Liu X, Kong X, Zhu L, Zhou B, Wang Y, Peng J, Zhu W, Wang J. Abstract 14239: Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve. Circulation. 2023;148(Supp 1):A14239 . |
Kif21a deficiency leads to impaired glomerular filtration barrier function
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Citation:
Sci Rep. 2023 Nov 6;13(1):19161. doi: 10.1038/s41598-023-46270-1 Epub:
Not Epub Abstract:
The renal glomerulus represents the major filtration body of the vertebrate nephron and is responsible for urine production and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Riedmann H, Kayser S, Helmstädter M, Epting D, Bergmann C. Kif21a deficiency leads to impaired glomerular filtration barrier function. Sci Rep. 2023 Nov 6;13(1):19161. doi: 10.1038/s41598-023-46270-1. |