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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Embryonic Ethanol but Not Cannabinoid Exposure Affects Zebrafish Cardiac Development via Agrin and Sonic Hedgehog Interaction
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Citation:
Cells. 2023 May 6;12(9):1327. doi: 10.3390/cells12091327 Epub:
Not Epub Abstract:
Recent studies demonstrate the adverse effects of cannabinoids on development, including via pathways shared with ethanol... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang C, Ezem N, Mackinnon S, Cole GJ. Embryonic Ethanol but Not Cannabinoid Exposure Affects Zebrafish Cardiac Development via Agrin and Sonic Hedgehog Interaction. Cells. 2023 May 6;12(9):1327. doi: 10.3390/cells12091327. |
The challenge of dissecting gene function in model organisms: Tools to characterize genetic mutants and assess transcriptional adaptation in zebrafish
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Citation:
Methods Cell Biol. 2023;176:1-25. doi: 10.1016/bs.mcb.2022.12.019. Epub 2023 Jan 27 Epub:
Not Epub Abstract:
Genome editing technologies including the CRISPR/Cas9 system have greatly improved our knowledge of gene function and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cardenas-Rodriguez M, Drummond IA. The challenge of dissecting gene function in model organisms: Tools to characterize genetic mutants and assess transcriptional adaptation in zebrafish. Methods Cell Biol. 2023;176:1-25. doi: 10.1016/bs.mcb.2022.12.019. Epub 2023 Jan 27. |
Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor
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Citation:
Elife. 2023 May 10;12:e84036. doi: 10.7554/eLife.84036. Online ahead of print Epub:
Yes Abstract:
Natriuretic peptide signaling has been implicated in a broad range of physiological processes, regulating blood volume and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Devotta A, Juraver-Geslin H, Griffin C, Saint-Jeannet JP. Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor. Elife. 2023 May 10;12:e84036. doi: 10.7554/eLife.84036. Online ahead of print. |
Efficacy and Safety of Viltolarsen in Boys With Duchenne Muscular Dystrophy: Results From the Phase 2, Open-Label, 4-Year Extension Study
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Citation:
J Neuromuscul Dis. 2023;10(3):439-447. doi: 10.3233/JND-221656 Epub:
Not Epub Abstract:
Background: Duchenne muscular dystrophy (DMD) is caused by DMD gene mutations, resulting in absence of functional dystrophin... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Clemens PR, Rao VK, Connolly AM, Harper AD, Mah JK, McDonald CM, Smith EC, Zaidman CM, Nakagawa T; CINRG DNHS Investigators; Hoffman EP. Efficacy and Safety of Viltolarsen in Boys With Duchenne Muscular Dystrophy: Results From the Phase 2, Open-Label, 4-Year Extension Study. J Neuromuscul Dis. 2023;10(3):439-447. doi: 10.3233/JND-221656. |
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
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Citation:
Nat Struct Mol Biol. 2024 Aug;31(8):1198-1207. doi: 10.1038/s41594-024-01265-y. Epub 2024 Apr 2. PMID: 38565696; PMCID: PMC11329362 Epub:
Not Epub Abstract:
The conversion of phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 3,4,5-triphosphate by phosphoinositide 3-kinase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen CL, Syahirah R, Ravala SK, Yen YC, Klose T, Deng Q, Tesmer JJG. Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ. Nat Struct Mol Biol. 2024 Aug;31(8):1198-1207. doi: 10.1038/s41594-024-01265-y. Epub 2024 Apr 2. PMID: 38565696; PMCID: PMC11329362. |
The phosphatidylinositol (4,5)-bisphosphate-Rab35 axis regulates migrasome formation
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Citation:
Cell Res. 2023;[Epub] doi:10.1038/s41422-023-00811-5 Epub:
Yes Abstract:
Migrasomes are recently discovered organelles, which are formed on the ends or branch points of retraction fibers at the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ding T, Ji J, Zhang W, Liu Y, Liu B, Han Y, Chen C, Yu L. The phosphatidylinositol (4,5)-bisphosphate-Rab35 axis regulates migrasome formation. Cell Res. 2023;[Epub] doi:10.1038/s41422-023-00811-5. |
In a zebrafish biomedical model of human Allan-Herndon-Dudley syndrome impaired MTH signaling leads to decreased neural cell diversity
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Citation:
Front Endocrinol. 2023;14:1157685. doi:10.3389/fendo.2023.1157685 Epub:
Not Epub Abstract:
Background: Maternally derived thyroid hormone (T3) is a fundamental factor for vertebrate neurodevelopment. In humans,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Silva N, Campinho MA. In a zebrafish biomedical model of human Allan-Herndon-Dudley syndrome impaired MTH signaling leads to decreased neural cell diversity. Front Endocrinol. 2023;14:1157685. doi:10.3389/fendo.2023.1157685. |
Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
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Citation:
Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2220911120. doi: 10.1073/pnas.2220911120. Epub 2023 May 1 Epub:
Not Epub Abstract:
Narcolepsy with cataplexy is a sleep disorder caused by deficiency in the hypothalamic neuropeptide hypocretin/orexin (HCRT),... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Seifinejad A, Ramosaj M, Shan L, Li S, Possovre ML, Pfister C, Fronczek R, Garrett-Sinha LA, Frieser D, Honda M, Arribat Y, Grepper D, Amati F, Picot M, Agnoletto A, Iseli C, Chartrel N, Liblau R, Lammers GJ, Vassalli A, Tafti M. Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2220911120. doi: 10.1073/pnas.2220911120. Epub 2023 May 1. |
Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells
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Citation:
Stem Cell Res Ther. 2023 Apr 30;14(1):117. doi: 10.1186/s13287-023-03328-1 Epub:
Not Epub Abstract:
Background: In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li H, Luo Q, Cai S, Tie R, Meng Y, Shan W, Xu Y, Zeng X, Qian P, Huang H. Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells. Stem Cell Res Ther. 2023 Apr 30;14(1):117. doi: 10.1186/s13287-023-03328-1. |
Epigenetic landscape reveals MECOM as an endothelial lineage regulator
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Citation:
Nat Commun. 2023;14:2390. doi:/10.1038/s41467-023-38002-w Epub:
Not Epub Abstract:
A comprehensive understanding of endothelial cell lineage specification will advance cardiovascular regenerative medicine.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lv J, Meng S, Gu Q, Zheng R, Gao X, Kim J-d, Chen M, Xia B, Zuo Y, Zhu S, Zhao D, Li Y, Wang G, Wang X, Meng Q, Cao Q, Cooke JP, Fang L, Chen K, Zhang L. Epigenetic landscape reveals MECOM as an endothelial lineage regulator. Nat Commun. 2023;14:2390. doi:/10.1038/s41467-023-38002-w. |