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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling
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Citation:
Biology. 2023; 12(4):538. https://doi.org/10.3390/biology12040538 Epub:
Not Epub Abstract:
Ribosomes are the vital molecular machine for protein translation in a cell. Defects in several nucleolar proteins have been... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liang F, Lu X, Wu B, Yang Y, Qin W. Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling. Biology. 2023; 12(4):538. https://doi.org/10.3390/biology12040538. |
Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length
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Citation:
Environ Sci Technol. 2023;57(15): 6139–49. doi:10.1021/acs.est.2c09716. Online ahead of print Epub:
Not Epub Abstract:
Previous studies have reported the immunotoxicity of per- and polyfluoroalkyl substances (PFASs), but it remains a significant... Organism or Cell Type:
zebrafish Citation Extract: Tang L, Qiu W, Zhang S, Wang J, Yang X, Xu B, Magnuson JT, Xu EG, Wu M, Zheng C. Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length. Environ Sci Technol. 2023;57(15): 6139–49. doi:10.1021/acs.est.2c09716. Online ahead of print. |
BDNF signaling in correlation-dependent structural plasticity in the developing visual system
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Citation:
PLoS Biol. 2023;21(4):e3002070. doi:10.1371/journal.pbio.3002070 Epub:
Not Epub Abstract:
During development, patterned neural activity instructs topographic map refinement. Axons with similar patterns of neural... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kutsarova E, Schohl A, Munz M, Wang A, Zhang YY, Bilash OM, Ruthazer ES. BDNF signaling in correlation-dependent structural plasticity in the developing visual system. PLoS Biol. 2023;21(4):e3002070. doi:10.1371/journal.pbio.3002070. |
Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation
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Citation:
eLife. 2023;12:e83652. doi:10.7554/eLife.83652 Epub:
Not Epub Abstract:
Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Buglak DB, Bougaran P, Kulikauskas MR, Liu Z, Monaghan-Benson E, Gold AL, Marvin AP, Burciu A, Tanke NT, Oatley M, Ricketts SN, Kinghorn K, Johnson BN, Shiau CE, Rogers S, Guilluy C, Bautch VL. Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation. eLife. 2023;12:e83652. doi:10.7554/eLife.83652. |
Inhibition of Interferon Alpha by a Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer Increases Influenza Virus Replication in Chicken Embryo Fibroblast (DF-1) Cells; An Alternative Strategy to Increasing Vaccine Production in Cell Culture
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Citation:
J Med Microbiol. 2024 Feb;73(2). doi: 10.1099/jmm.0.001807. PMID: 38353513 Epub:
Not Epub Abstract:
Influenza is a global health issue causing substantial health and economic burdens in affected populations. Routine, annual... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: DF-1 chick embryo fibroblasts Citation Extract: Prescott M, Moulton H, Pastey M. Inhibition of Interferon Alpha by a Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer Increases Influenza Virus Replication in Chicken Embryo Fibroblast (DF-1) Cells; An Alternative Strategy to Increasing Vaccine Production in Cell Culture. J Med Microbiol. 2024 Feb;73(2). doi: 10.1099/jmm.0.001807. PMID: 38353513. |
In Vivo Evaluation of Exon 51 Skipping in hDMD/Dmd-null Mice
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Citation:
Methods Mol Biol. 2023;2640:327-336. doi: 10.1007/978-1-0716-3036-5_23. PMID: 36995605 Epub:
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Duchenne muscular dystrophy (DMD) is a fatal X-linked condition that affects 1 in 3500-6000 newborn boys a year. An out-of-... Delivery Method:
intravenous (i.v.) and intramuscular (i.m.) injections Organism or Cell Type:
mice Citation Extract: Sheri N, Yokota T. In Vivo Evaluation of Exon 51 Skipping in hDMD/Dmd-null Mice. Methods Mol Biol. 2023;2640:327-336. doi: 10.1007/978-1-0716-3036-5_23. PMID: 36995605. |
Exons 45-55 Skipping Using Antisense Oligonucleotides in Immortalized Human DMD Muscle Cells
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Citation:
Methods Mol Biol. 2023;2640:313-325. doi: 10.1007/978-1-0716-3036-5_22. Epub:
Not Epub Abstract:
Antisense oligonucleotides (AOs) have demonstrated high potential as a therapy for treating genetic diseases like Duchene... Organism or Cell Type:
cell culture: immortalized DMD muscle cell lines Citation Extract: He M, Yokota T. Exons 45-55 Skipping Using Antisense Oligonucleotides in Immortalized Human DMD Muscle Cells. Methods Mol Biol. 2023;2640:313-325. doi: 10.1007/978-1-0716-3036-5_22.. |
ASO targeting RBM3 temperature-controlled poison exon splicing prevents neurodegeneration in vivo
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Citation:
EMBO Mol Med. 2023 Mar 22:e17157. doi: 10.15252/emmm.202217157. Online ahead of print Epub:
Yes Abstract:
Neurodegenerative diseases are increasingly prevalent in the aging population, yet no disease-modifying treatments are... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Preußner M, Smith HL, Hughes D, Zhang M, Emmerichs AK, Scalzitti S, Peretti D, Swinden D, Neumann A, Haltenhof T, Mallucci GR, Heyd F. ASO targeting RBM3 temperature-controlled poison exon splicing prevents neurodegeneration in vivo. EMBO Mol Med. 2023 Mar 22:e17157. doi: 10.15252/emmm.202217157. Online ahead of print. |
Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
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Citation:
Mol Cancer. 2023 Mar 18;22(1):55. doi:10.1186/s12943-023-01759-1 Epub:
Not Epub Abstract:
Background: Circular RNAs (circRNAs) can be encapsulated into exosomes to participate in intercellular communication, affecting... Organism or Cell Type:
cell culture: primary human hepatocellular carcinoma (HCC) Citation Extract: Hu Z, Chen G, Zhao Y, Gao H, Li L, Yin Y, Jiang J, Wang L, Mang Y, Gao Y, Zhang S, Ran J, Li L. Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma. Mol Cancer. 2023 Mar 18;22(1):55. doi:10.1186/s12943-023-01759-1. |
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms
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Citation:
Commun Biol. 2023;6:295. doi:10.1038/s42003-023-04667-8 Epub:
Not Epub Abstract:
Prolactin (PRL) is elevated in B-cell-mediated lymphoproliferative diseases and promotes B-cell survival. Whether PRL or PRL... Delivery Method:
Alzet osmotic pump Vivo-Morpholino Organism or Cell Type:
NOD-SCID IL2Rγ−/− (NSG) mice xenografted Citation Extract: Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki C, Aramburo S, Lee SJ, Hu Z, Damirchi B,Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM. Swaminathan S. Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Commun Biol. 2023;6:295. doi:10.1038/s42003-023-04667-8. |