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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12419 scientific papers returned from the database with the search filters currently being used below.

The dystrophin associated protein complex in zebrafish

Authors:
Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM
Citation:
Hum Mol Genet 2003 Mar 15;12(6):601-15
Epub:
Not Epub
Abstract:
Many cases of muscular dystrophy in humans are caused by mutations in members of the dystrophin associated protein complex (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM. The dystrophin associated protein complex in zebrafish. Hum Mol Genet 2003 Mar 15;12(6):601-15.

The INT6 Cancer Gene and MEK Signaling Pathways Converge during Zebrafish Development

Authors:
Grzmil M, Whiting D, Maule J, Anastasaki C, Amatruda JF, Kelsh RN, Norbury CJ, Patton EE
Citation:
PLoS ONE. 2007 Sep 26;2(9):e959
Epub:
Not Epub
Abstract:
BACKGROUND: Int-6 (integration site 6) was identified as an oncogene in a screen of tumorigenic mouse mammary tumor virus (MMTV...
Organism or Cell Type:
zebrafish
Citation Extract:
Grzmil M, Whiting D, Maule J, Anastasaki C, Amatruda JF, Kelsh RN, Norbury CJ, Patton EE. The INT6 Cancer Gene and MEK Signaling Pathways Converge during Zebrafish Development. PLoS ONE. 2007 Sep 26;2(9):e959.

The lmx1b gene is pivotal in glomus development in Xenopus laevis

Authors:
Haldin CE, Massé KL, Bhamra S, Simrick S, Kyuno JI, Jones EA
Citation:
Dev Biol. 2008 Jul 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We have previously shown that lmx1b, a LIM homeodomain protein, is expressed in the pronephric glomus. We now show temporal and...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haldin CE, Massé KL, Bhamra S, Simrick S, Kyuno JI, Jones EA. The lmx1b gene is pivotal in glomus development in Xenopus laevis. Dev Biol. 2008 Jul 21. [Epub ahead of print].

The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity

Authors:
Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH
Citation:
J Clin Invest. 2007 Dec;117(12):3940-51
Epub:
Not Epub
Abstract:
Statins inhibit HMG-CoA reductase, a key enzyme in cholesterol synthesis, and are widely used to treat hypercholesterolemia....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH. The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. J Clin Invest. 2007 Dec;117(12):3940-51.

The neuroepithelial basement membrane serves as a boundary and a substrate for neuron migration in the zebrafish hindbrain

Authors:
Grant PK, Moens CB
Citation:
Neural Dev. 2010 Mar 29;5(1):9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: The facial branchiomotor neurons of cranial nerve VII undergo a stereotyped tangential migration in the...
Organism or Cell Type:
zebrafish
Citation Extract:
Grant PK, Moens CB. The neuroepithelial basement membrane serves as a boundary and a substrate for neuron migration in the zebrafish hindbrain. Neural Dev. 2010 Mar 29;5(1):9. [Epub ahead of print].

The Opitz syndrome gene MID1 is essential for establishing asymmetric gene expression in Hensen's node

Authors:
Granata A, Quaderi NA
Citation:
Dev Biol. 2003 Jun 15;258(2):397-405
Epub:
Not Epub
Abstract:
Patterning the avian left-right (L/R) body axis involves the establishment of asymmetric molecular signals on the left and...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Granata A, Quaderi NA. The Opitz syndrome gene MID1 is essential for establishing asymmetric gene expression in Hensen's node. Dev Biol. 2003 Jun 15;258(2):397-405.

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development

Authors:
Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH
Citation:
Nat Cell Biol. 2009 Oct;11(10):1225-32. Epub 2009 Sep 20
Epub:
Not Epub
Abstract:
The planar cell polarity (PCP) signalling pathway is essential for embryonic development because it governs diverse cellular...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol. 2009 Oct;11(10):1225-32. Epub 2009 Sep 20.

The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development.

Authors:
Gross I, Morrison DJ, Hyink DP, Georgas K, English MA, Mericskay M, Hosono S, Sassoon D, Wilson PD, Little M, Licht JD.
Citation:
J Biol Chem. 2003 Oct 17;278(42):41420-30. Epub 2003 Jul 25.
Epub:
Not Epub
Abstract:
WT1 encodes a transcription factor involved in kidney development and tumorigenesis. Using representational difference analysis...
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse kidney explants, embryonic
Citation Extract:
Gross I, Morrison DJ, Hyink DP, Georgas K, English MA, Mericskay M, Hosono S, Sassoon D, Wilson PD, Little M, Licht JD.. The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development.. J Biol Chem. 2003 Oct 17;278(42):41420-30. Epub 2003 Jul 25..

The small GTPase RhoV is an essential regulator of neural crest induction in Xenopus

Authors:
Guemar L, de Santa Barbara P, Vignal E, Maurel B, Fort P, Faure S
Citation:
Dev Biol. 2007 Oct 1;310(1):113-28. Epub 2007 Aug 2.
Epub:
Not Epub
Abstract:
In vertebrates, the Rho family of GTPases is made of 20 members which regulate a variety of cellular functions, including actin...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Guemar L, de Santa Barbara P, Vignal E, Maurel B, Fort P, Faure S. The small GTPase RhoV is an essential regulator of neural crest induction in Xenopus. Dev Biol. 2007 Oct 1;310(1):113-28. Epub 2007 Aug 2..

The transcriptional activator ZNF143 is essential for normal development in zebrafish

Authors:
Halbig KM, Lekven AC, Kunkel GR
Citation:
BMC Mol Biol. 2012;13:3 doi:10.1186/1471-2199-13-3
Epub:
Not Epub
Abstract:
Background ZNF143 is a sequence-specific DNA-binding protein that stimulates transcription of both small RNA genes by RNA...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Halbig KM, Lekven AC, Kunkel GR. The transcriptional activator ZNF143 is essential for normal development in zebrafish. BMC Mol Biol. 2012;13:3 doi:10.1186/1471-2199-13-3.

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