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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Future Physiology 2020 (Virutal) Oral Communications: A zebrafish model of embryonic growth disruption reveals an ongoing impact on metabolic and cardiac phenotype
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Proc Physiol Soc. 2020;46:OC03 Epub:
Not Epub Abstract:
As climate change continues to pose a global problem, the need to understand organisms immediate and ongoing responses to the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Evans B. Future Physiology 2020 (Virutal) Oral Communications: A zebrafish model of embryonic growth disruption reveals an ongoing impact on metabolic and cardiac phenotype. Proc Physiol Soc. 2020;46:OC03. |
Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor
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https://www.pnas.org/content/118/28/e2102562118 Epub:
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Here, we report that important regulators of cilia formation and ciliary compartment-directed protein transport function in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Leventea E, Zhu Z, Fang X, Nikolaeva Y, Markham E, Hirst RA, van Eeden FJM, Malicki JJ. Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor. https://www.pnas.org/content/118/28/e2102562118. |
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons
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PLoS Genet. 2021;17(7):e1009647. doi:10.1371/journal.pgen.1009647 Epub:
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The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hahn I, Voelzmann A, Parkin J, Fuelle J, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A. Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. PLoS Genet. 2021;17(7):e1009647. doi:10.1371/journal.pgen.1009647. |
Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling
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Citation:
Sci Rep. 2021 Jul 6;11(1):13940. doi: 10.1038/s41598-021-93440-0 Epub:
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The Hedgehog (Hh)/Gli signaling pathway controls cell proliferation and differentiation, is critical for the development of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Serifi I, Besta S, Karetsou Z, Giardoglou P, Beis D, Niewiadomski P, Papamarcaki T. Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling. Sci Rep. 2021 Jul 6;11(1):13940. doi: 10.1038/s41598-021-93440-0. |
The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line
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Citation:
Biochimie. 2021 Jun 29:S0300-9084(21)00158-9. doi: 10.1016/j.biochi.2021.06.013. Online ahead of print Epub:
Yes Abstract:
Zebrafish is broadly used as a model organism in gene loss-of-function studies in vivo, but its employment in vitro is greatly... Delivery Method:
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cell culture: zebrafish lines Citation Extract: Hu X, Gao S, Wang P, Zhou Y, Chen K, Chen Q, Wang B, Hu W, Cheng P, Eid R, Giraud-Panis MJ, Wang L, Gilson E, Ye J, Lu Y.. The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line. Biochimie. 2021 Jun 29:S0300-9084(21)00158-9. doi: 10.1016/j.biochi.2021.06.013. Online ahead of print. |
Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy
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Citation:
Pharmacol Res. 2021;[Epub] doi:10.1016/j.phrs.2021.105750 Epub:
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Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle degeneration and currently there are few therapeutic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Spreafico M, Cafora M, Bragato C, Capitanio D, Marasca F, Bodega B, De Palma C, Mora M, Gelfi C, Marozzi A, Pistocchi A. Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy. Pharmacol Res. 2021;[Epub] doi:10.1016/j.phrs.2021.105750. |
Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes
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Citation:
J Dev Biol. 2021;9(3):25. doi:10.3390/jdb9030025 Epub:
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Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA. Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR)... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA
. Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes. J Dev Biol. 2021;9(3):25. doi:10.3390/jdb9030025. |
Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis
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Citation:
Genet Med. 2021;[Epub] doi:10.1038/s41436-021-01237-3 Epub:
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Purpose: Congenital hypothyroidism (CH) is a common congenital endocrine disorder in humans. CH-related diseases such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang R-M, Zhan M, Zhou Q-Y, Ye X-P, Wu F-Y, Dong M, Sun F, Fang Y, Zhang R-J, Zhang C-R, Yang L, Guo M-M, Zhang J-X, Liang J, Cheng F, Liu W, Han B, Zhou Y, Zhao S-X, Song H-D. Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis. Genet Med. 2021;[Epub] doi:10.1038/s41436-021-01237-3. |
LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy
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Citation:
EMBO J. 2021 Jun 28:e107134. doi:10.15252/embj.2020107134. Online ahead of print. https://www.embopress.org/doi/full/10.15252/embj.2020107134 Epub:
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Long non-coding RNAs (lncRNAs) are emerging as key regulators of endothelial cell function. Here, we investigated the role of a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sehgal P, Mathew S, Sivadas A, Ray A, Tanwar J, Vishwakarma S, Ranjan G, Shamsudheen KV, Bhoyar RC, Pateria A, Leonard E, Lalwani M, Vats A, Pappuru RR, Tyagi M, Jakati S, Sengupta S, B K B, Chakrabarti S, Kaur I, Motiani RK, Scaria V, Sivasubbu S. LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy. EMBO J. 2021 Jun 28:e107134. doi:10.15252/embj.2020107134. Online ahead of print. https://www.embopress.org/doi/full/10.15252/embj.2020107134. |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
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Citation:
Nat Commun. 2021;12(1):4032. doi:10.1038/s41467-021-24346-8 Epub:
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In animals, body axis patterning is based on the concentration-dependent interpretation of graded morphogen signals, which... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Lebedeva T, Aman AJ, Graf T, Niedermoser I, Zimmermann B, Kraus Y, Schatka M, Demilly A, Technau U, Genikhovich G. Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning. Nat Commun. 2021;12(1):4032. doi:10.1038/s41467-021-24346-8. |