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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

Authors:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S
Citation:
PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006
Epub:
Not Epub
Abstract:
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei...
Link:
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008006
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006.

Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

Authors:
Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW
Citation:
eLife. 2019;8:e51447. doi:10.7554/eLife.51447
Epub:
Not Epub
Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by...
Link:
https://elifesciences.org/articles/51447
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. eLife. 2019;8:e51447. doi:10.7554/eLife.51447.

Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia

Authors:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM
Citation:
Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to...
Link:
https://dev.biologists.org/content/early/2019/12/10/dev.185231
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM. Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia. Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print].

AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos

Authors:
Ren F, Ji C, Huang Y, Aniagu S, Jiang Y, Chen T
Citation:
Sci Total Environ. 2019 Nov 21:135097. doi: 10.1016/j.scitotenv.2019.135097. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent studies have shown an association between maternal exposure to ambient fine particle matter (PM2.5) and congenital heart...
Link:
https://www.sciencedirect.com/science/article/pii/S0048969719350892
Organism or Cell Type:
zebrafish
Citation Extract:
Ren F, Ji C, Huang Y, Aniagu S, Jiang Y, Chen T. AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos. Sci Total Environ. 2019 Nov 21:135097. doi: 10.1016/j.scitotenv.2019.135097. [Epub ahead of print].

Gene duplication and functional divergence of the zebrafish otospiralin genes

Authors:
Aissette B, Sepand R, Amal B, Masanari T, Vanessa G, Amal S, Tanja B, Olfa J, Uwe S, Saber M
Citation:
Dev Genes Evol. 2019 Dec 14. doi: 10.1007/s00427-019-00642-8. [Epub ahead of print]
Epub:
Yes
Abstract:
Otospiralin (OTOSP) is a small protein of unknown function, expressed in fibrocytes of the inner ear and required for normal...
Link:
https://link.springer.com/article/10.1007%2Fs00427-019-00642-8
Organism or Cell Type:
zebrafish
Citation Extract:
Aissette B, Sepand R, Amal B, Masanari T, Vanessa G, Amal S, Tanja B, Olfa J, Uwe S, Saber M. Gene duplication and functional divergence of the zebrafish otospiralin genes. Dev Genes Evol. 2019 Dec 14. doi: 10.1007/s00427-019-00642-8. [Epub ahead of print].

Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9

Authors:
Sun Y, Zhang B, Luo L, Shi DL, Wang H, Cui Z, Huang H, Cao Y, Shu X, Zhang W, Zhou J, Li Y, Du J, Zhao Q, Chen J, Zhong H, Zhong TP, Li L, Xiong JW, Peng J, Xiao W, Zhang J, Yao J, Yin Z, Mo X, Peng G, Zhu J, Chen Y, Zhou Y, Liu D, Pan W, Zhang Y, Ruan H, Liu F, Zhu Z, Meng A; ZAKOC Consortium
Citation:
Genome Res. 2019 Dec 12. doi: 10.1101/gr.248559.119. [Epub ahead of print]
Epub:
Yes
Abstract:
Genome editing by the well-established CRISPR/Cas9 technology has greatly facilitated our understanding of many biological...
Link:
https://genome.cshlp.org/content/early/2019/12/12/gr.248559.119.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Zhang B, Luo L, Shi DL, Wang H, Cui Z, Huang H, Cao Y, Shu X, Zhang W, Zhou J, Li Y, Du J, Zhao Q, Chen J, Zhong H, Zhong TP, Li L, Xiong JW, Peng J, Xiao W, Zhang J, Yao J, Yin Z, Mo X, Peng G, Zhu J, Chen Y, Zhou Y, Liu D, Pan W, Zhang Y, Ruan H, Liu F, Zhu Z, Meng A; ZAKOC Consortium. Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome Res. 2019 Dec 12. doi: 10.1101/gr.248559.119. [Epub ahead of print].

Ectoderm to mesoderm transition by downregulation of actomyosin contractility

Authors:
Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/870444
Epub:
Not Epub
Abstract:
Collective migration of cohesive tissues is a fundamental process in morphogenesis, and is particularly well illustrated during...
Link:
https://www.biorxiv.org/content/10.1101/870444v2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F. Ectoderm to mesoderm transition by downregulation of actomyosin contractility. bioRxiv. 2019;[preprint] doi:10.1101/870444.

DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells

Authors:
Suhail A, Rizvi ZA, Mujagond P, Ali SA, Gaur P, Singh M, Ahuja V, Awasthi A, Srikanth CV
Citation:
Cell Rep. 2019 Dec 10;29(11):3522-3538.e7. doi: 10.1016/j.celrep.2019.11.028
Epub:
Not Epub
Abstract:
Inflammatory bowel disease (IBD) is a complex autoimmune disorder recently shown to be associated with SUMOylation, a post-...
Link:
https://www.sciencedirect.com/science/article/pii/S2211124719314998
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Suhail A, Rizvi ZA, Mujagond P, Ali SA, Gaur P, Singh M, Ahuja V, Awasthi A, Srikanth CV. DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells. Cell Rep. 2019 Dec 10;29(11):3522-3538.e7. doi: 10.1016/j.celrep.2019.11.028.

Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development

Authors:
Lawir DF, Hess I, Sikora K, Iwanami N, Siamishi I, Schorpp M, Boehm T
Citation:
Proc Natl Acad Sci U S A. 2019 Dec 10. pii: 201915223. doi: 10.1073/pnas.1915223116. [Epub ahead of print]
Epub:
Yes
Abstract:
In mammals, T cell development critically depends on the IL-7 cytokine signaling pathway. Here we describe the identification...
Link:
https://www.pnas.org/content/early/2019/12/09/1915223116
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lawir DF, Hess I, Sikora K, Iwanami N, Siamishi I, Schorpp M, Boehm T. Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proc Natl Acad Sci U S A. 2019 Dec 10. pii: 201915223. doi: 10.1073/pnas.1915223116. [Epub ahead of print].

p53 Protects Cells from Death at the Heatstroke Threshold Temperature

Authors:
Gong L, Zhang Q, Pan X, Chen S, Yang L, Liu B, Yang W, Yu L, Xiao ZX, Feng XH, Wang H, Yuan ZM, Peng J, Tan WQ, Chen J
Citation:
Cell Rep. 2019 Dec 10;29(11):3693-3707.e5. doi: 10.1016/j.celrep.2019.11.032
Epub:
Not Epub
Abstract:
When the core body temperature is higher than 40°C, life is threatened due to heatstroke. Tumor repressor p53 is required for...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31514-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong L, Zhang Q, Pan X, Chen S, Yang L, Liu B, Yang W, Yu L, Xiao ZX, Feng XH, Wang H, Yuan ZM, Peng J, Tan WQ, Chen J. p53 Protects Cells from Death at the Heatstroke Threshold Temperature. Cell Rep. 2019 Dec 10;29(11):3693-3707.e5. doi: 10.1016/j.celrep.2019.11.032.

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