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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

MARCKS phosphorylation by PKC strongly impairs cell polarity in the chick neural plate

Authors:
Aparicio G, Arruti C, Zolessi FR
Citation:
Genesis. 2018 Mar 30. doi: 10.1002/dvg.23104. [Epub ahead of print]
Epub:
Yes
Abstract:
Neurulation involves a complex coordination of cellular movements that are in great part based on the modulation of the actin...
Link:
https://onlinelibrary.wiley.com/doi/pdf/10.1002/dvg.23104
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Aparicio G, Arruti C, Zolessi FR. MARCKS phosphorylation by PKC strongly impairs cell polarity in the chick neural plate. Genesis. 2018 Mar 30. doi: 10.1002/dvg.23104. [Epub ahead of print].

Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease

Authors:
Sribudiani Y, Chauhan RK, Alves MM, Petrova L, Brosens E, Harrison C, Wabbersen T, de Graaf BM, Rügenbrink T, Burzynski G, Brouwer RWW, IJcken WFJV, Maas SM, de Klein A, Osinga J, Eggen BJL, Burns AJ, Brooks AS, Shepherd IT, Hofstra RMW
Citation:
Gastroenterology. 2018 Mar 27. pii: S0016-5085(18)30341-X. doi: 10.1053/j.gastro.2018.03.034. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND & AIMS: Hirschsprung disease (HSCR) is an inherited congenital disorder characterized by absence of enteric...
Link:
http://www.gastrojournal.org/article/S0016-5085(18)30341-X/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sribudiani Y, Chauhan RK, Alves MM, Petrova L, Brosens E, Harrison C, Wabbersen T, de Graaf BM, Rügenbrink T, Burzynski G, Brouwer RWW, IJcken WFJV, Maas SM, de Klein A, Osinga J, Eggen BJL, Burns AJ, Brooks AS, Shepherd IT, Hofstra RMW. Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease. Gastroenterology. 2018 Mar 27. pii: S0016-5085(18)30341-X. doi: 10.1053/j.gastro.2018.03.034. [Epub ahead of print].

Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects

Authors:
Tian T, Wang L, Shen Y, Zhang B, Finnell RH, Ren A
Citation:
Epigenomics. 2018 Mar 28. doi: 10.2217/epi-2018-0016. [Epub ahead of print]
Epub:
Yes
Abstract:
AIM: To investigate the relationship between GRHL3 methylation and the etiology of neural tube defects (NTDs). MATERIALS...
Link:
https://www.futuremedicine.com/doi/abs/10.2217/epi-2018-0016
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tian T, Wang L, Shen Y, Zhang B, Finnell RH, Ren A. Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects. Epigenomics. 2018 Mar 28. doi: 10.2217/epi-2018-0016. [Epub ahead of print].

An APOO Pseudogene on Chromosome 5q is Associated with LDL-C Levels

Authors:
Montasser ME, O'Hare EA, Wang X, Howard AD, McFarland R, Perry JA, Ryan KA, Rice K, Jaquish CE, Shuldiner AR, Miller M, Mitchell BD, Zaghloul NA, Chang Y-PC
Citation:
Circulation. 2018;[Epub ahead of print] doi:10.1161/CIRCULATIONAHA.118.034016
Epub:
Not Epub
Abstract:
Background: Elevated levels of low-density lipoprotein cholesterol (LDL-C) are a major risk factor for CVD via its contribution...
Link:
http://circ.ahajournals.org/content/early/2018/03/27/CIRCULATIONAHA.118.034016
Organism or Cell Type:
zebrafish
Citation Extract:
Montasser ME, O'Hare EA, Wang X, Howard AD, McFarland R, Perry JA, Ryan KA, Rice K, Jaquish CE, Shuldiner AR, Miller M, Mitchell BD, Zaghloul NA, Chang Y-PC. An APOO Pseudogene on Chromosome 5q is Associated with LDL-C Levels. Circulation. 2018;[Epub ahead of print] doi:10.1161/CIRCULATIONAHA.118.034016.

miR-206 is required for changes in cell adhesion that drive muscle cell morphogenesis in Xenopus laevis

Authors:
Vergara HM, Ramirez J, Rosing T, Nave C, Blandino R, Saw D, Saraf P, Piexoto G, Coombes C, Adams M, Domingo CR
Citation:
Dev Biol. 2018;[Epub ahead of print] doi:10.1016/j.ydbio.2018.03.021
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are highly conserved small non-coding RNA molecules that post-transcriptionally regulate gene expression in...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617307285
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vergara HM, Ramirez J, Rosing T, Nave C, Blandino R, Saw D, Saraf P, Piexoto G, Coombes C, Adams M, Domingo CR. miR-206 is required for changes in cell adhesion that drive muscle cell morphogenesis in Xenopus laevis. Dev Biol. 2018;[Epub ahead of print] doi:10.1016/j.ydbio.2018.03.021.

C8orf46 homolog encodes a novel protein Vexin that is required for neurogenesis in Xenopus laevis

Authors:
Moore KB, Logan MA, Aldiri I, Roberts JM, Steele M, Vetter ML
Citation:
Dev Biol. 2018 Mar 5. pii: S0012-1606(17)30810-2. doi: 10.1016/j.ydbio.2018.03.003. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural basic helix-loop helix (bHLH) transcription factors promote progenitor cell differentiation by activation of downstream...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617308102
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Moore KB, Logan MA, Aldiri I, Roberts JM, Steele M, Vetter ML. C8orf46 homolog encodes a novel protein Vexin that is required for neurogenesis in Xenopus laevis. Dev Biol. 2018 Mar 5. pii: S0012-1606(17)30810-2. doi: 10.1016/j.ydbio.2018.03.003. [Epub ahead of print].

Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation

Authors:
Hall CJ, Sanderson LE, Lawrence LM, Pool B, van der Kroef M, Ashimbayeva E, Britto D, Harper JL, Lieschke GJ, Astin JW, Crosier KE, Dalbeth N, Crosier PS
Citation:
J Clin Invest. 2018 Mar 26. pii: 94584. doi: 10.1172/JCI94584. [Epub ahead of print]
Epub:
Yes
Abstract:
Gout is the most common inflammatory arthritis affecting men. Acute gouty inflammation is triggered by monosodium urate (MSU)...
Link:
https://www.jci.org/articles/view/94584
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hall CJ, Sanderson LE, Lawrence LM, Pool B, van der Kroef M, Ashimbayeva E, Britto D, Harper JL, Lieschke GJ, Astin JW, Crosier KE, Dalbeth N, Crosier PS. Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation. J Clin Invest. 2018 Mar 26. pii: 94584. doi: 10.1172/JCI94584. [Epub ahead of print].

Whole-Genome Linkage Analysis with Whole-Exome Sequencing Identifies a Novel Frameshift Variant in NEFH in a Chinese Family with Charcot-Marie-Tooth 2: A Novel Variant in NEFH for Charcot-Marie-Tooth 2

Authors:
Bian X, Lin P, Li J, Long F, Duan R, Yuan Q, Li Y, Gao F, Gao S, Wei S, Li X, Sun W, Gong Y, Yan C, Liu Q
Citation:
Neurodegener Dis. 2018 Mar 27;18(2-3):74-83. doi: 10.1159/000487754. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Charcot-Marie-Tooth disease (CMT) is the most common neurodegenerative disorder of the peripheral nervous system....
Link:
https://www.karger.com/Article/Abstract/487754
Organism or Cell Type:
zebrafish
Citation Extract:
Bian X, Lin P, Li J, Long F, Duan R, Yuan Q, Li Y, Gao F, Gao S, Wei S, Li X, Sun W, Gong Y, Yan C, Liu Q. Whole-Genome Linkage Analysis with Whole-Exome Sequencing Identifies a Novel Frameshift Variant in NEFH in a Chinese Family with Charcot-Marie-Tooth 2: A Novel Variant in NEFH for Charcot-Marie-Tooth 2. Neurodegener Dis. 2018 Mar 27;18(2-3):74-83. doi: 10.1159/000487754. [Epub ahead of print].

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia

Authors:
Danilova N, Wilkes M, Bibikova E, Youn M-Y, Sakamoto KM, Lin S
Citation:
Sci Rep. 2018;8:5165. doi:10.1038/s41598-018-23561-6
Epub:
Not Epub
Abstract:
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and...
Link:
https://www.nature.com/articles/s41598-018-23561-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Danilova N, Wilkes M, Bibikova E, Youn M-Y, Sakamoto KM, Lin S. Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Sci Rep. 2018;8:5165. doi:10.1038/s41598-018-23561-6.

Counterregulation of cAMP-directed kinase activities controls ciliogenesis

Authors:
Porpora M, Sauchella S, Rinaldi L, Donne RD, Sepe M, Torres-Quesada O, Intartaglia D, Garbi C, Insabato L, Santoriello M, Bachmann VA, Synofzik M, Lindner HH, Conte I, Stefan E, Feliciello A
Citation:
Nat Comm. 2018;9:1224. doi:10.1038/s41467-018-03643-9
Epub:
Not Epub
Abstract:
The primary cilium emanates from the cell surface of growth-arrested cells and plays a central role in vertebrate development...
Link:
https://www.nature.com/articles/s41467-018-03643-9
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Porpora M, Sauchella S, Rinaldi L, Donne RD, Sepe M, Torres-Quesada O, Intartaglia D, Garbi C, Insabato L, Santoriello M, Bachmann VA, Synofzik M, Lindner HH, Conte I, Stefan E, Feliciello A. Counterregulation of cAMP-directed kinase activities controls ciliogenesis. Nat Comm. 2018;9:1224. doi:10.1038/s41467-018-03643-9.

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