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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures
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Citation:
Elife. 2016 May 10;5. pii: e10557. doi: 10.7554/eLife.10557 Epub:
Not Epub Abstract:
Genetic variants identified by genome-wide association studies explain only a modest proportion of heritability, suggesting... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, Newton-Cheh C, Milan DJ, Kellis M, Boyer LA. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 2016 May 10;5. pii: e10557. doi: 10.7554/eLife.10557. |
Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment
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Citation:
PLoS One. 2016 May 10;11(5):e0155032. doi: 10.1371/journal.pone.0155032. eCollection 2016 Epub:
Not Epub Abstract:
Gastrointestinal (GI) defects, including gastroesophageal reflux, constipation and delayed gastric emptying, are common in... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
mice Citation Extract: Sintusek P, Catapano F, Angkathunkayul N, Marrosu E, Parson SH, Morgan JE, Muntoni F, Zhou H. Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment. PLoS One. 2016 May 10;11(5):e0155032. doi: 10.1371/journal.pone.0155032. eCollection 2016. |
Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia
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Citation:
bioRxiv. 2016. doi:10.1101/052209 Epub:
Yes Abstract:
Over 100 genetic loci harbor schizophrenia associated variants, yet how these common variants confer risk is uncertain. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gumus ZH, Cicek AE, Dang K, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Parvisi M, Hamamsy T, Fullard JF, Wang Y-C, Mahajan MC, Derry JMJ, Dudley J, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn C-G, Lewis DA, Haroutonian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hira K, Roeder K, Brennand KJ, Katsanis N, Dominici E, Devlin B, Sklar P. Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia. bioRxiv. 2016. doi:10.1101/052209. |
The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development
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Citation:
Dev Cell. 2016;37(3):213-25. doi:10.1016/j.devcel.2016.04.008 Epub:
Not Epub Abstract:
Radial intercalation is a fundamental process responsible for the thinning of multilayered tissues during large-scale... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Szabó A, Cobo I, Omara S, McLachlan S, Keller R, Mayor R
. The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development. Dev Cell. 2016;37(3):213-25. doi:10.1016/j.devcel.2016.04.008. |
History and Properties of Morpholino Antisense Oligos
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Citation:
J Drug Discov Develop and Deliv. 2016; 3(1): 1019 Epub:
Not Epub Abstract:
This paper provides a very brief overview of the beginning of the antisense field, including the first antisense structural... Link:
Citation Extract: Summerton J. History and Properties of Morpholino Antisense Oligos. J Drug Discov Develop and Deliv. 2016; 3(1): 1019. |
Custom Cocktail for Curing any Cancer: A Strategy for Destroying any Cancer without Harming the Patient
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Citation:
J Drug Discov Develop and Deliv. 2016; 3(1): 1020 Epub:
Not Epub Abstract:
Drugs for curing any cancer must completely destroy a patient’s cancer
without harming the patient. To avoid harming the... Link:
Citation Extract: Summerton J. Custom Cocktail for Curing any Cancer: A Strategy for Destroying any Cancer without Harming the Patient. J Drug Discov Develop and Deliv. 2016; 3(1): 1020. |
MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation
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Citation:
Dev Cell. 2013 Feb 11;24(3):283-95. doi: 10.1016/j.devcel.2012.12.016. Epub:
Not Epub Abstract:
Craniofacial malformations are common structural birth defects and usually associate with abnormal development of pharyngeal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ning G, Liu X, Dai M, Meng A, Wang Q.. MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation. Dev Cell. 2013 Feb 11;24(3):283-95. doi: 10.1016/j.devcel.2012.12.016.. |
A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo
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Citation:
PLoS Genet. 2016;12(5):e1006045. doi:10.1371/journal.pgen.1006045 Epub:
Yes Abstract:
Maternal factors initiate the zygotic developmental program in animal embryos. In embryos of the chordate, Ciona intestinalis,... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Oda-Ishii I, Kubo A, Kari W, Suzuki N, Rothbächer U, Satou Y. A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo. PLoS Genet. 2016;12(5):e1006045. doi:10.1371/journal.pgen.1006045. |
RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish
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Citation:
Development. 2016;[Epub ahead of print] doi: 10.1242/dev.126797 Epub:
Yes Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are capable of self-renewal and replenishing all lineages of blood cells... Organism or Cell Type:
zebrafish Citation Extract: Wei Y, Xu J, Zhang W, Wen Z, Liu F. RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish. Development. 2016;[Epub ahead of print] doi: 10.1242/dev.126797. |
Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2
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Citation:
Sci Rep. 2016;6:24658. doi: 10.1038/srep24658 Epub:
Not Epub Abstract:
Polycomb group (PcG) proteins are transcriptional repressors of numerous genes, many of which regulate cell cycle progression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: San B, Chrispijn ND, Wittkopp N, van Heeringen SJ, Lagendijk AK, Aben M, Bakkers J, Ketting RF, Kamminga LM. Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2. Sci Rep. 2016;6:24658. doi: 10.1038/srep24658. |