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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor

Authors:
Mirando AC, Fang P, Williams TF, Baldor LC, Howe AK, Ebert AM, Wilkinson B, Lounsbury KM, Guo M, Francklyn CS
Citation:
Sci Rep. 2015 Aug 14;5:13160. doi: 10.1038/srep13160
Epub:
Not Epub
Abstract:
Aminoacyl-tRNA synthetases (AARSs) catalyze an early step in protein synthesis, but also regulate diverse physiological...
Link:
http://www.nature.com/articles/srep13160
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mirando AC, Fang P, Williams TF, Baldor LC, Howe AK, Ebert AM, Wilkinson B, Lounsbury KM, Guo M, Francklyn CS. Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor. Sci Rep. 2015 Aug 14;5:13160. doi: 10.1038/srep13160.

RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1

Authors:
Ear J, Huang H, Wilson T, Tehrani Z, Lindgren A, Sung V, Laadem A, Daniel TO, Chopra R, Lin S
Citation:
Blood. 2015 Aug 13;126(7):880-90. doi: 10.1182/blood-2015-01-622522. Epub 2015 Jun 24
Epub:
Not Epub
Abstract:
Diamond-Blackfan Anemia (DBA) is a bone marrow failure disorder characterized by low red blood cell count. Mutations in...
Link:
http://www.bloodjournal.org/content/126/7/880
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ear J, Huang H, Wilson T, Tehrani Z, Lindgren A, Sung V, Laadem A, Daniel TO, Chopra R, Lin S. RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood. 2015 Aug 13;126(7):880-90. doi: 10.1182/blood-2015-01-622522. Epub 2015 Jun 24.

RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish

Authors:
Frese KS, Meder B, Keller A, Just S, Haas J, Vogel B, Fischer S, Backes C, Matzas M, Köhler D, Benes V, Katus HA, Rottbauer W
Citation:
J Cell Sci. 2015 Aug 15;128(16):3030-40. doi: 10.1242/jcs.166850. Epub 2015 Jun 26
Epub:
Not Epub
Abstract:
Alternative splicing is one of the major mechanisms through which the proteomic and functional diversity of eukaryotes is...
Link:
http://jcs.biologists.org/content/128/16/3030.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Frese KS, Meder B, Keller A, Just S, Haas J, Vogel B, Fischer S, Backes C, Matzas M, Köhler D, Benes V, Katus HA, Rottbauer W. RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish. J Cell Sci. 2015 Aug 15;128(16):3030-40. doi: 10.1242/jcs.166850. Epub 2015 Jun 26.

β-Arrestin1 Regulates Morphology and Dynamics of Microglia in Zebrafish in Vivo

Authors:
Li Y, Du X, Pei G, Du J, Zhao J
Citation:
Eur J Neurosci. 2015 Sep 10. doi: 10.1111/ejn.13065. [Epub ahead of print]
Epub:
Yes
Abstract:
Microglia are the primary immune cells in the central nervous system. Microglia typically exist in a "resting" state...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/ejn.13065/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Du X, Pei G, Du J, Zhao J. β-Arrestin1 Regulates Morphology and Dynamics of Microglia in Zebrafish in Vivo. Eur J Neurosci. 2015 Sep 10. doi: 10.1111/ejn.13065. [Epub ahead of print].

Two novel COLVI long chains in zebrafish that are essential for muscle development

Authors:
Ramanoudjame L, Rocancourt C, Lainé J, Klein A, Joassard L, Gartioux C, Fleury M, Lyphout L, Kabashi E, Ciura S, Cousin X, Allamand V
Citation:
Hum Mol Genet. 2015 Sep 11. pii: ddv368. [Epub ahead of print]
Epub:
Yes
Abstract:
Collagen VI (COLVI), a protein ubiquitously expressed in connective tissues, is crucial for structural integrity, cellular...
Link:
http://hmg.oxfordjournals.org/content/early/2015/09/11/hmg.ddv368.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ramanoudjame L, Rocancourt C, Lainé J, Klein A, Joassard L, Gartioux C, Fleury M, Lyphout L, Kabashi E, Ciura S, Cousin X, Allamand V. Two novel COLVI long chains in zebrafish that are essential for muscle development. Hum Mol Genet. 2015 Sep 11. pii: ddv368. [Epub ahead of print].

ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning

Authors:
Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV
Citation:
Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023
Epub:
Not Epub
Abstract:
The ciliary kinase NEK8 plays a critical role in situs determination and cystic kidney disease, yet its exact function remains...
Link:
http://www.nature.com/ncomms/2015/150120/ncomms7023/full/ncomms7023.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, Lo CW, Beier DR, Shah JV. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nat Commun. 2015 Jan 20;6:6023. doi: 10.1038/ncomms7023.

TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells

Authors:
Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW
Citation:
Nucleic Acids Res. 2015 Aug 10. pii: gkv816. [Epub ahead of print]
Epub:
Yes
Abstract:
PSF (a.k.a. SFPQ) is a ubiquitously expressed, essential nuclear protein with important roles in DNA damage repair and RNA...
Link:
http://nar.oxfordjournals.org/content/early/2015/08/09/nar.gkv816.full
Organism or Cell Type:
cell culture: JSL1 cells
Citation Extract:
Yarosh CA, Tapescu I, Thompson MG, Qiu J, Mallory MJ, Fu XD, Lynch KW. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res. 2015 Aug 10. pii: gkv816. [Epub ahead of print].

Luminal signalling links cell communication to tissue architecture during organogenesis

Authors:
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D
Citation:
Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22
Epub:
Not Epub
Abstract:
Morphogenesis is the process whereby cell collectives are shaped into differentiated tissues and organs. The self-organizing...
Link:
http://www.nature.com/nature/journal/v515/n7525/full/nature13852.html
Citation Extract:
Durdu S, Iskar M, Revenu C, Schieber N, Kunze A, Bork P, Schwab Y, Gilmour D. Luminal signalling links cell communication to tissue architecture during organogenesis. Nature. 2014 Nov 6;515(7525):120-4. doi: 10.1038/nature13852. Epub 2014 Oct 22.

Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy

Authors:
Gonzaga-Jauregui C, Harel T, Gambin T, Kousi M, Griffin LB, Francescatto L, Ozes B, Karaca E, Jhangiani SN, Bainbridge MN, Lawson KS, Pehlivan D, Okamoto Y, Withers M, Mancias P, Slavotinek A, Reitnauer PJ, Goksungur MT, Shy M, Crawford TO, Koenig M, Willer J, Flores BN, Pediaditrakis I, Us O, Wiszniewski W, Parman Y, Antonellis A, Muzny DM; Baylor-Hopkins Center for Mendelian Genomics, Katsanis N, Battaloglu E, Boerwinkle E, Gibbs RA, Lupski JR
Citation:
Cell Rep. 2015 Aug 18;12(7):1169-83. doi: 10.1016/j.celrep.2015.07.023. Epub 2015 Aug 6
Epub:
Not Epub
Abstract:
Charcot-Marie-Tooth (CMT) disease is a clinically and genetically heterogeneous distal symmetric polyneuropathy. Whole-exome...
Link:
http://www.sciencedirect.com/science/article/pii/S2211124715007639
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gonzaga-Jauregui C, Harel T, Gambin T, Kousi M, Griffin LB, Francescatto L, Ozes B, Karaca E, Jhangiani SN, Bainbridge MN, Lawson KS, Pehlivan D, Okamoto Y, Withers M, Mancias P, Slavotinek A, Reitnauer PJ, Goksungur MT, Shy M, Crawford TO, Koenig M, Willer J, Flores BN, Pediaditrakis I, Us O, Wiszniewski W, Parman Y, Antonellis A, Muzny DM; Baylor-Hopkins Center for Mendelian Genomics, Katsanis N, Battaloglu E, Boerwinkle E, Gibbs RA, Lupski JR. Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015 Aug 18;12(7):1169-83. doi: 10.1016/j.celrep.2015.07.023. Epub 2015 Aug 6.

Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence

Authors:
Li C, Lan Y, Schwartz-Orbach L, Korol E, Tahiliani M, Evans T, Goll MG
Citation:
Cell Rep. 2015 Aug 18;12(7):1133-43. doi: 10.1016/j.celrep.2015.07.025. Epub 2015 Aug 6
Epub:
Not Epub
Abstract:
The Tet family of methylcytosine dioxygenases (Tet1, Tet2, and Tet3) convert 5-methylcytosine to 5-hydroxymethylcytosine. To...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(15)00765-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li C, Lan Y, Schwartz-Orbach L, Korol E, Tahiliani M, Evans T, Goll MG. Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Rep. 2015 Aug 18;12(7):1133-43. doi: 10.1016/j.celrep.2015.07.025. Epub 2015 Aug 6.

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