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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo

Authors:
Eagleson G, Pfister K, Knowlton AL, Skoglund P, Keller R, Stukenberg PT
Citation:
Mol Biol Cell. 2015 Mar 1;26(5):924-37. doi: 10.1091/mbc.E13-12-0721. Epub 2015 Jan 7
Epub:
Not Epub
Abstract:
Kif2a is a member of the kinesin-13 microtubule depolymerases, which tightly regulate microtubule dynamics for many cellular...
Link:
http://www.molbiolcell.org/content/26/5/924.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Eagleson G, Pfister K, Knowlton AL, Skoglund P, Keller R, Stukenberg PT. Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo. Mol Biol Cell. 2015 Mar 1;26(5):924-37. doi: 10.1091/mbc.E13-12-0721. Epub 2015 Jan 7.

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

Authors:
Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R
Citation:
Nucleic Acids Res. 2015 Mar 3. pii: gkv157. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in FUS cause amyotrophic lateral sclerosis (ALS), but the molecular pathways leading to neurodegeneration remain...
Link:
http://nar.oxfordjournals.org/content/early/2015/03/02/nar.gkv157.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R. U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish. Nucleic Acids Res. 2015 Mar 3. pii: gkv157. [Epub ahead of print].

Epigenetic control of intestinal barrier function and inflammation in zebrafish

Authors:
Marjoram L, Alvers A, Deerhake ME, Bagwell J, Mankiewicz J, Cocchiaro JL, Beerman RW, Willer J, Sumigray KD, Katsanis N, Tobin DM, Rawls JF, Goll MG, Bagnat M
Citation:
Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2770-5. doi: 10.1073/pnas.1424089112. Epub 2015 Feb 17
Epub:
Not Epub
Abstract:
The intestinal epithelium forms a barrier protecting the organism from microbes and other proinflammatory stimuli. The...
Link:
http://www.pnas.org/content/112/9/2770.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marjoram L, Alvers A, Deerhake ME, Bagwell J, Mankiewicz J, Cocchiaro JL, Beerman RW, Willer J, Sumigray KD, Katsanis N, Tobin DM, Rawls JF, Goll MG, Bagnat M. Epigenetic control of intestinal barrier function and inflammation in zebrafish. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2770-5. doi: 10.1073/pnas.1424089112. Epub 2015 Feb 17.

IFT46 plays an essential role in cilia development

Authors:
Lee MS, Hwang KS, Oh HW, Ji-Ae K, Kim HT, Cho HS, Lee JJ, Yeong Ko J, Choi JH, Jeong YM, You KH, Kim J, Park DS, Nam KH, Aizawa S, Kiyonari H, Shioi G, Park JH, Zhou W, Kim NS, Kim CH
Citation:
Dev Biol. 2015 Feb 24. pii: S0012-1606(15)00067-6. doi: 10.1016/j.ydbio.2015.02.009. [Epub ahead of print]
Epub:
Yes
Abstract:
Cilia are microtubule-based structures that project into the extracellular space. Ciliary defects are associated with several...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615000676
Organism or Cell Type:
zebrafish
Citation Extract:
Lee MS, Hwang KS, Oh HW, Ji-Ae K, Kim HT, Cho HS, Lee JJ, Yeong Ko J, Choi JH, Jeong YM, You KH, Kim J, Park DS, Nam KH, Aizawa S, Kiyonari H, Shioi G, Park JH, Zhou W, Kim NS, Kim CH. IFT46 plays an essential role in cilia development. Dev Biol. 2015 Feb 24. pii: S0012-1606(15)00067-6. doi: 10.1016/j.ydbio.2015.02.009. [Epub ahead of print].

Biochemical Characterization of Three BLT Receptors in Zebrafish

Authors:
Okuno T, Ishitani T, Yokomizo T
Citation:
PLoS One. 2015 Mar 4;10(3):e0117888. doi: 10.1371/journal.pone.0117888. eCollection 2015
Epub:
Not Epub
Abstract:
The leukotriene B4 (LTB4) receptor 1 (BLT1) is a high affinity receptor for LTB4, a chemotactic and inflammatory eicosanoid....
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117888
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okuno T, Ishitani T, Yokomizo T. Biochemical Characterization of Three BLT Receptors in Zebrafish. PLoS One. 2015 Mar 4;10(3):e0117888. doi: 10.1371/journal.pone.0117888. eCollection 2015.

Morpholino-functionalized nanochannel array for label-free single nucleotide polymorphisms detection.

Authors:
Gao HL, Wang M, Wu ZQ, Wang C, Wang K, Xia XH
Citation:
Anal Chem. 2015 Apr 7;87(7):3936-41. doi: 10.1021/ac504830e. Epub 2015 Mar 11.
Epub:
Yes
Abstract:
The sensitive identification of single nucleotide polymorphisms becomes increasing important for disease diagnosis, prevention...
Link:
http://pubs.acs.org/doi/abs/10.1021/ac504830e
Citation Extract:
Gao HL, Wang M, Wu ZQ, Wang C, Wang K, Xia XH. Morpholino-functionalized nanochannel array for label-free single nucleotide polymorphisms detection.. Anal Chem. 2015 Apr 7;87(7):3936-41. doi: 10.1021/ac504830e. Epub 2015 Mar 11..

Etv2 and Fli1b Function Together as Key Regulators of Vasculogenesis and Angiogenesis

Authors:
Craig MP, Grajevskaja V, Liao HK, Balciuniene J, Ekker SC, Park JS, Essner JJ, Balciunas D, Sumanas S
Citation:
Arterioscler Thromb Vasc Biol. 2015 Feb 26. pii: ATVBAHA.114.304768. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: The E26 transformation-specific domain transcription factor Etv2/Etsrp/ER71 is a master regulator of vascular...
Link:
http://atvb.ahajournals.org/content/early/2015/02/26/ATVBAHA.114.304768.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Craig MP, Grajevskaja V, Liao HK, Balciuniene J, Ekker SC, Park JS, Essner JJ, Balciunas D, Sumanas S. Etv2 and Fli1b Function Together as Key Regulators of Vasculogenesis and Angiogenesis. Arterioscler Thromb Vasc Biol. 2015 Feb 26. pii: ATVBAHA.114.304768. [Epub ahead of print].

Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling

Authors:
Sheng R, Kim H, Lee H, Xin Y, Chen Y, Tian W, Cui Y, Choi JC, Doh J, Han JK, Cho W
Citation:
Nat Commun. 2014 Jul 15;5:4393. doi: 10.1038/ncomms5393
Epub:
Not Epub
Abstract:
Wnt proteins control diverse biological processes through β-catenin-dependent canonical signalling and β-catenin-independent...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100210/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sheng R, Kim H, Lee H, Xin Y, Chen Y, Tian W, Cui Y, Choi JC, Doh J, Han JK, Cho W. Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling. Nat Commun. 2014 Jul 15;5:4393. doi: 10.1038/ncomms5393.

Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesis

Authors:
Opitz R, Hitz MP, Vandernoot I, Trubiroha A, Abu-Khudir R, Samuels M, Désilets V, Costagliola S, Andelfinger G, Deladoëy J
Citation:
Endocrinology. 2015 Jan;156(1):377-88. doi: 10.1210/en.2014-1628
Epub:
Not Epub
Abstract:
Congenital hypothyroidism caused by thyroid dysgenesis (CHTD) is a common congenital disorder with a birth prevalence of 1 case...
Link:
http://press.endocrine.org/doi/abs/10.1210/en.2014-1628
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Opitz R, Hitz MP, Vandernoot I, Trubiroha A, Abu-Khudir R, Samuels M, Désilets V, Costagliola S, Andelfinger G, Deladoëy J. Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesis. Endocrinology. 2015 Jan;156(1):377-88. doi: 10.1210/en.2014-1628.

A Novel Mutation in the α-Myosin Heavy Chain Gene Is Associated with Sick Sinus Syndrome

Authors:
Ishikawa T, Jou CJ, Nogami A, Kowase S, Arrington CB, Barnett SM, Harrell DT, Arimura T, Tsuji Y, Kimura A, Makita N
Citation:
Circ Arrhythm Electrophysiol. 2015 Feb 25. pii: CIRCEP.114.002534. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: -Recent genome-wide association studies have demonstrated an association between MYH6, the gene encoding α-myosin...
Link:
http://circep.ahajournals.org/content/early/2015/02/25/CIRCEP.114.002534.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Ishikawa T, Jou CJ, Nogami A, Kowase S, Arrington CB, Barnett SM, Harrell DT, Arimura T, Tsuji Y, Kimura A, Makita N. A Novel Mutation in the α-Myosin Heavy Chain Gene Is Associated with Sick Sinus Syndrome. Circ Arrhythm Electrophysiol. 2015 Feb 25. pii: CIRCEP.114.002534. [Epub ahead of print].

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