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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12208 scientific papers returned from the database with the search filters currently being used below.
There are 12208 scientific papers returned from the database with the search filters currently being used below.
Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish
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Citation:
JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971 Epub:
Not Epub Abstract:
Deterioration or inborn malformations of the cardiac conduction system (CCS) interfere with proper impulse propagation in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann W-H, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M. Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971. |
Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia
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Citation:
G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585 Epub:
Yes Abstract:
Ribosome is a vital molecular machine for protein translation in the cell. Defects in several ribosomal proteins including... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng Chen, Haigen Huang, Ruibin Yan, Shuo Lin and Wei Qin. Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585. |
Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo
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Citation:
Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4 Epub:
Not Epub Abstract:
Morphogen signalling forms an activity gradient and instructs cell identities in a signalling strength-dependent manner to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4. |
POPDC3 gene variants associate with a new form of limb girdle muscular dystrophy
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Citation:
Ann Neurol. 2019 Oct 14. doi: 10.1002/ana.25620. [Epub ahead of print] Epub:
Yes Abstract:
OBJECTIVE: The Popeye domain containing 3 (POPDC3) gene encodes a membrane protein involved in cAMP signaling. Besides gastric... Organism or Cell Type:
zebrafish Citation Extract: Vissing J, Johnson K, Töpf A, Nafissi S, Díaz-Manera J, French VM, Schindler RF, Sarathchandra P, Løkken N, Rinné S, Freund M, Decher N, Müller T, Duno M, Krag T, Brand T, Straub V. POPDC3 gene variants associate with a new form of limb girdle muscular dystrophy. Ann Neurol. 2019 Oct 14. doi: 10.1002/ana.25620. [Epub ahead of print]. |
Silencing Breast Cancer Genes using Morpholino Embedded DNA-Tile-AuNPs Nanostructures
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Citation:
Hum Gene Ther. 2019 Oct 14. doi: 10.1089/hum.2019.119. [Epub ahead of print] Epub:
Not Epub Abstract:
There is an ongoing effort to increase the efficiency of gene delivery for the regulation of diseases related genes. In this... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: breast cancer Citation Extract: Tunç CÜ, Öztaş DY, Uzunoglu D, Bayrak ÖF, Culha M. Silencing Breast Cancer Genes using Morpholino Embedded DNA-Tile-AuNPs Nanostructures. Hum Gene Ther. 2019 Oct 14. doi: 10.1089/hum.2019.119. [Epub ahead of print]. |
Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1-/- zebrafish
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Citation:
Eur J Neurosci. 2017 Feb;45(4):528-535. doi: 10.1111/ejn.13473. Epub 2016 Dec 28 Epub:
Not Epub Abstract:
Mutations in PTEN-induced putative kinase 1 (PINK1) are a cause of early onset Parkinson's disease (PD). Loss of PINK1... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Soman S, Keatinge M, Moein M, Da Costa M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O. Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1-/- zebrafish. Eur J Neurosci. 2017 Feb;45(4):528-535. doi: 10.1111/ejn.13473. Epub 2016 Dec 28. |
CTENO64 Is Required for Coordinated Paddling of Ciliary Comb Plate in Ctenophores
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Citation:
Curr Biol. 2019;29:[Epub in press] doi:10.1016/j.cub.2019.08.059 Epub:
Yes Abstract:
Ctenophores, or comb jellies, are one of the earliestbranching basal metazoan groups, whose phyloge-netic position continues to... Delivery Method:
microinjection Organism or Cell Type:
Bolinopsis mikado (Ctenophore, comb jelly) Citation Extract: Jokura K, Shibata D, Yamaguchi K, Shiba K, Makino Y, Shigenobu S, Inaba K. CTENO64 Is Required for Coordinated Paddling of Ciliary Comb Plate in Ctenophores. Curr Biol. 2019;29:[Epub in press] doi:10.1016/j.cub.2019.08.059. |
Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides
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Citation:
Int J Mol Sci. 2019;20(20):5030. doi:10.3390/ijms20205030 Epub:
Not Epub Abstract:
The process of pre-mRNA splicing is a common and fundamental step in the expression of most human genes. Alternative splicing,... Citation Extract: Aung-Htut MT, McIntosh CS, Ham KA, Pitout IL, Flynn LL, Greer K, Fletcher S, Wilton SD. Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides. Int J Mol Sci. 2019;20(20):5030. doi:10.3390/ijms20205030. |
Oct4 mediates Müller glia reprogramming and cell cycle exit during retina regeneration in zebrafish
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Citation:
Life Sci Alliance. 2019 Oct 8;2(5). pii: e201900548. doi: 10.26508/lsa.201900548. Print 2019 Oct Epub:
Not Epub Abstract:
Octamer-binding transcription factor 4 (Oct4, also known as Pou5F3) is an essential pluripotency-inducing factor, governing a... Delivery Method:
ocular injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Sharma P, Gupta S, Chaudhary M, Mitra S, Chawla B, Khursheed MA, Ramachandran R. Oct4 mediates Müller glia reprogramming and cell cycle exit during retina regeneration in zebrafish. Life Sci Alliance. 2019 Oct 8;2(5). pii: e201900548. doi: 10.26508/lsa.201900548. Print 2019 Oct. |
Spliceosomal disruption of the non-canonical BAF complex in cancer
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Citation:
Nature. 2019;[Epub ahead of print] doi:10.1038/s41586-019-1646-9 Epub:
Yes Abstract:
SF3B1 is the most commonly mutated RNA splicing factor in cancer1–4, but the mechanisms by which SF3B1 mutations promote... Delivery Method:
intratumoral injection Organism or Cell Type:
cell culture: MEL202 cells (SF3B1R625G) xenografted in mice Citation Extract: Inoue D, Chew G-L, Liu B, Michel BC, Pangallo J, D’Avino AR, Hitchman T, North K, Lee SC-W, Bitner L, Block A, Moore AR, Yoshimi A, Escobar-Hoyos L, Cho H, Penson A, Lu SX, Taylor J, Chen Y, Kadoch C, Abdel-Wahab O, Bradley RK. Spliceosomal disruption of the non-canonical BAF complex in cancer. Nature. 2019;[Epub ahead of print] doi:10.1038/s41586-019-1646-9. |