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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12208 scientific papers returned from the database with the search filters currently being used below.

Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome

Authors:
Brenet A, Hassan-Abdi R, Somkhit J, Yanicostas C, Soussi-Yanicostas N
Citation:
Cells. 2019 Oct 4;8(10):1199. doi: 10.3390/cells8101199. PMID: 31590334; PMCID: PMC6829503
Epub:
Not Epub
Abstract:
Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic drugs. In recent years,...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6829503/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brenet A, Hassan-Abdi R, Somkhit J, Yanicostas C, Soussi-Yanicostas N. Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome. Cells. 2019 Oct 4;8(10):1199. doi: 10.3390/cells8101199. PMID: 31590334; PMCID: PMC6829503.

Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation

Authors:
Marinović Z, Li Q, Lujić J, Iwasaki Y, Csenki Z, Urbányi B, Yoshizaki G, Horváth Á
Citation:
Sci Rep. 2019;9(1):13681. doi:10.1038/s41598-019-50169-1
Epub:
Not Epub
Abstract:
Zebrafish is one of the most commonly used model organisms in biomedical, developmental and genetic research. The production of...
Link:
https://www.nature.com/articles/s41598-019-50169-1
Citation Extract:
Marinović Z, Li Q, Lujić J, Iwasaki Y, Csenki Z, Urbányi B, Yoshizaki G, Horváth Á. Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation. Sci Rep. 2019;9(1):13681. doi:10.1038/s41598-019-50169-1.

Characterization of biklf/klf17-deficient zebrafish in posterior lateral line neuromast and hatching gland development

Authors:
Suzuki H, Ishizaka T, Yanagi K, Sone R, Sunaga Y, Ohga R, Kawahara A
Citation:
Sci Rep. 2019;9(1):13680. doi:10.1038/s41598-019-50149-5
Epub:
Not Epub
Abstract:
Krüpple-like factors (Klfs) are highly conserved zinc-finger transcription factors that regulate various developmental...
Link:
https://www.nature.com/articles/s41598-019-50149-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Suzuki H, Ishizaka T, Yanagi K, Sone R, Sunaga Y, Ohga R, Kawahara A. Characterization of biklf/klf17-deficient zebrafish in posterior lateral line neuromast and hatching gland development. Sci Rep. 2019;9(1):13680. doi:10.1038/s41598-019-50149-5.

Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface

Authors:
Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J
Citation:
ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print]
Epub:
Yes
Abstract:
Monoclonal antibody therapy has offered treatment benefits. Nonetheless, lack of efficacy still exists, partially because...
Link:
https://pubs.acs.org/doi/10.1021/acsnano.9b04868
Organism or Cell Type:
mice
Citation Extract:
Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J. Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface. ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print].

Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis

Authors:
Havrilak JA, Layden MJ
Citation:
Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2
Epub:
Not Epub
Abstract:
The cnidarian sea anemone Nematostella vectensis has grown in popularity as a model system to complement the ongoing work in...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-9732-9_2
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Havrilak JA, Layden MJ. Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis. Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2.

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063
Epub:
Yes
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31118-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063.

lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish

Authors:
Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X
Citation:
J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237
Epub:
Yes
Abstract:
lncrps25 is an intergenic long noncoding RNA (lncRNA), which is location close to rps25 (ribosomal protein S25) gene, is...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.29237
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X. lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish. J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237.

Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b

Authors:
Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y
Citation:
PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print]
Epub:
Yes
Abstract:
During vertebrate early embryogenesis, the ventral development is directed by the ventral-to-dorsal activity gradient of the...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008306
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print].

Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis

Authors:
Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U
Citation:
Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print]
Epub:
Yes
Abstract:
Morphogenesis is a shape-building process during development of multicellular organisms. During this process the establishment...
Link:
https://dev.biologists.org/content/early/2019/09/19/dev.174623.long
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U. Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis. Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print].

Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner

Authors:
Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF
Citation:
Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Insufficient delivery of oligonucleotides to muscle and heart remains a barrier for clinical implementation of antisense...
Link:
http://www.sciencedirect.com/science/article/pii/S2162253119302598
Delivery Method:
peptide-linked; intravenous (i.v.)
Organism or Cell Type:
mice mdx
Citation Extract:
Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF. Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner. Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print].

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