You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs
|
Citation:
Methods Mol Biol. 2018;1828:365-379. doi: 10.1007/978-1-4939-8651-4_23 Epub:
Not Epub Abstract:
Exon skipping is an emerging approach to treating Duchenne muscular dystrophy (DMD), one of the most common lethal genetic... Delivery Method:
peptide-linked Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Maruyama R, Aoki Y, Takeda S, Yokota T. In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs. Methods Mol Biol. 2018;1828:365-379. doi: 10.1007/978-1-4939-8651-4_23. |
A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers
|
Citation:
Methods Mol Biol. 2018;1828:293-306. doi: 10.1007/978-1-4939-8651-4_18 Epub:
Not Epub Abstract:
Morpholino oligomers have great therapeutic potential for treatment of a broad range of human diseases, including viral,... Delivery Method:
peptide-linked Organism or Cell Type:
zebrafish Citation Extract: Kim J, Clark K, Barton C, Tanguay R, Moulton H. A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers. Methods Mol Biol. 2018;1828:293-306. doi: 10.1007/978-1-4939-8651-4_18. |
In Vivo Evaluation of Single-Exon and Multiexon Skipping in mdx52 Mice
|
Citation:
Methods Mol Biol. 2018;1828:275-292. doi: 10.1007/978-1-4939-8651-4_17 Epub:
Not Epub Abstract:
Exon-skipping therapy is an emerging approach that uses synthetic DNA-like molecules called antisense oligonucleotides (ASOs)... Organism or Cell Type:
mice mdx52 Citation Extract: Mizobe Y, Miyatake S, Takizawa H, Hara Y, Yokota T, Nakamura A, Takeda S, Aoki Y. In Vivo Evaluation of Single-Exon and Multiexon Skipping in mdx52 Mice. Methods Mol Biol. 2018;1828:275-292. doi: 10.1007/978-1-4939-8651-4_17. |
Systemic Injection of Peptide-PMOs into Humanized DMD Mice and Evaluation by RT-PCR and ELISA
|
Citation:
Methods Mol Biol. 2018;1828:263-273. doi: 10.1007/978-1-4939-8651-4_16 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder due to the lack of dystrophin production. The disease is... Delivery Method:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_16 Organism or Cell Type:
mice Citation Extract: Melo D, Maruyama R, Yokota T. Systemic Injection of Peptide-PMOs into Humanized DMD Mice and Evaluation by RT-PCR and ELISA. Methods Mol Biol. 2018;1828:263-273. doi: 10.1007/978-1-4939-8651-4_16. |
Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment
|
Citation:
Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13 Epub:
Not Epub Abstract:
Duplications of one or more dystrophin exons that disrupt the reading frame account for about 15% of all Duchenne cases, and... Delivery Method:
peptide-linked Citation Extract: Greer K, Fletcher S, Wilton SD. Skipping of Duplicated Dystrophin Exons: In Vitro Induction and Assessment. Methods Mol Biol. 2018;1828:219-228. doi: 10.1007/978-1-4939-8651-4_13. |
In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient
|
Citation:
Methods Mol Biol. 2018;1828:151-163. doi: 10.1007/978-1-4939-8651-4_9 Epub:
Not Epub Abstract:
Antisense oligonucleotide induced exon skipping emerges as a promising therapeutic strategy for patients suffering from a... Organism or Cell Type:
cell culture: canine and human fibroblasts differentiated to myotubes Citation Extract: Nakamura A, Aoki Y, Tsoumpra M, Yokota T, Takeda S. In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient. Methods Mol Biol. 2018;1828:151-163. doi: 10.1007/978-1-4939-8651-4_9. |
Tips to Design Effective Splice-Switching Antisense Oligonucleotides for Exon Skipping and Exon Inclusion
|
Citation:
Methods Mol Biol. 2018;1828:79-90. doi: 10.1007/978-1-4939-8651-4_5 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping and exon inclusion have proven to be powerful tools for treating neuromuscular diseases. The... Citation Extract: Maruyama R, Yokota T. Tips to Design Effective Splice-Switching Antisense Oligonucleotides for Exon Skipping and Exon Inclusion. Methods Mol Biol. 2018;1828:79-90. doi: 10.1007/978-1-4939-8651-4_5. |
Bapx1 is required for jaw joint development in amphibians
|
Citation:
Evol Dev. 2018 Nov;20(6):192-206. doi:10.1111/ede.12267 Epub:
Not Epub Abstract:
The acquisition of a movable jaw and a jaw joint are key events in gnathostome evolution. Jaws are derived from the neural... Citation Extract: Lukas P, Olsson L.
. Bapx1 is required for jaw joint development in amphibians. Evol Dev. 2018 Nov;20(6):192-206. doi:10.1111/ede.12267. |
Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum
|
Citation:
Anal Chem. 2018 Aug 29. doi: 10.1021/acs.analchem.8b02330. [Epub ahead of print] Epub:
Yes Abstract:
Micro total analysis systems (μTAS) have been extensively developed for the detection of nucleic acids (NAs) in resource-... Citation Extract: Ouyang W, Li Z, Han J. Pressure-Modulated Selective Electrokinetic Trapping for Direct Enrichment, Purification, and Detection of Nucleic Acids in Human Serum. Anal Chem. 2018 Aug 29. doi: 10.1021/acs.analchem.8b02330. [Epub ahead of print]. |
Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa
|
Citation:
PLoS Genet. 2018;14(8):e1007504. doi:10.1371/journal.pgen.1007504 Epub:
Not Epub Abstract:
We identified a homozygous missense alteration (c.75C>A, p.D25E) in CLCC1, encoding a presumptive intracellular chloride... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li L, Jiao X, D’Atri I, Ono F, Nelson R, Chan C-C, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Akdemir ZHC, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Firoz Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF. Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS Genet. 2018;14(8):e1007504. doi:10.1371/journal.pgen.1007504. |