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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae
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Citation:
Front Cell Neurosci. 2018 Aug 21;12:257. doi: 10.3389/fncel.2018.00257. eCollection 2018. Epub:
Yes Abstract:
Zebrafish (Danio rerio) larvae are widely used to study otic functions because they possess all five typical vertebrate senses... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun P, Zhang Y, Zhao F, Wu J-P, Pun SH, Peng C, Du M, Vai MI, Liu D, Chen F. An Assay for Systematically Quantifying the Vestibulo-Ocular Reflex to Assess Vestibular Function in Zebrafish Larvae. Front Cell Neurosci. 2018 Aug 21;12:257. doi: 10.3389/fncel.2018.00257. eCollection 2018. . |
The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis
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Citation:
PLoS Genet. 2018 Aug 17;14(8):e1007590. doi: 10.1371/journal.pgen.1007590. [Epub ahead of print] Epub:
Not Epub Abstract:
Small non-coding RNAs (sRNAs) such as microRNAs (miRNAs), small interfering RNAs (siRNAs) and piwi-interacting RNAs (piRNAs)... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Modepalli V, Fridrich A, Agron M, Moran Y. The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis. PLoS Genet. 2018 Aug 17;14(8):e1007590. doi: 10.1371/journal.pgen.1007590. [Epub ahead of print]. |
A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease
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Citation:
Sci Rep. 2018 Aug 17;8(1):12386. doi: 10.1038/s41598-018-30204-3 Epub:
Not Epub Abstract:
Heterotaxy syndrome (HTX) is characterized by left-right (LR) asymmetry disturbances associated with severe heart malformations... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li S, Liu S, Chen W, Yuan Y, Gu R, Song Y, Li J, Cao Y, Lin Y, Xu J, Wang H, Ma D, Ma X, Sheng W, Huang G. A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease. Sci Rep. 2018 Aug 17;8(1):12386. doi: 10.1038/s41598-018-30204-3. |
Inhibiting neutral amino acid transport for the treatment of phenylketonuria
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Citation:
JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. [Epub ahead of print] Epub:
Not Epub Abstract:
The neuropathological effects of phenylketonuria (PKU) stem from the inability of the body to metabolize excess phenylalanine (... Delivery Method:
Endo-Porter in culture, peptide-linked in mice Organism or Cell Type:
cell culture: primary mouse renal tubular epithelial cells, mice Citation Extract: Belanger AM, Przybylska M, Gefteas E, Furgerson M, Geller S, Kloss A, Cheng SH, Zhu Y, Yew NS. Inhibiting neutral amino acid transport for the treatment of phenylketonuria. JCI Insight. 2018 Jul 26;3(14). pii: 121762. doi: 10.1172/jci.insight.121762. [Epub ahead of print]. |
Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking
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Citation:
JCI Insight. 2018 Jul 26;3(14). pii: 121596. doi: 10.1172/jci.insight.121596. [Epub ahead of print] Epub:
Not Epub Abstract:
Site-1 protease (S1P), encoded by MBTPS1, is a serine protease in the Golgi. S1P regulates lipogenesis, endoplasmic reticulum (... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human primary fibroblasts, immortalized Citation Extract: Kondo Y, Fu J, Wang H, Hoover C, McDaniel JM, Steet R, Patra D, Song J, Pollard L, Cathey S, Yago T, Wiley G, Macwana S, Guthridge J, McGee S, Li S, Griffin C, Furukawa K, James JA, Ruan C, McEver RP, Wierenga KJ, Gaffney PM, Xia L. Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking. JCI Insight. 2018 Jul 26;3(14). pii: 121596. doi: 10.1172/jci.insight.121596. [Epub ahead of print]. |
Long non-coding RNAs are largely dispensable for zebrafish embryogenesis, viability and fertility
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Citation:
bioRXive. 2018;[Epub] doi:10.1101/374702 Epub:
Yes Abstract:
Hundreds of long non-coding RNAs (lncRNAs) have been identified as potential regulators of gene expression, but their functions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mehdi Goudarzi, Kathryn Berg, Lindsey M Pieper, Alexander F Schier. Long non-coding RNAs are largely dispensable for zebrafish embryogenesis, viability and fertility. bioRXive. 2018;[Epub] doi:10.1101/374702. |
Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner
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Citation:
Elife. 2018 Jul 23;7. pii: e34404. doi: 10.7554/eLife.34404 Epub:
Not Epub Abstract:
Neural crest progenitors are specified through the modulation of several signaling pathways, among which the activation of Wnt/... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Devotta A, Hong CS, Saint-Jeannet JP. Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner. Elife. 2018 Jul 23;7. pii: e34404. doi: 10.7554/eLife.34404. |
Positive-feedback defines the timing and robustness of angiogenesis
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Citation:
bioRXive. 2018;[Epub] doi:10.1101/374389 Epub:
Not Epub Abstract:
Blood vessel formation by angiogenesis is critical for tissue development, homeostasis and repair, and is frequently... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Page DJ, Thuret R, Venkatraman L, Takahashi T, Bentley K, Herbert SP. Positive-feedback defines the timing and robustness of angiogenesis. bioRXive. 2018;[Epub] doi:10.1101/374389. |
A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis
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Citation:
BMC Biol. 2018 Jul 16;16(1):79. doi: 10.1186/s12915-018-0540-5 Epub:
Not Epub Abstract:
BACKGROUND: The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Maharana SK, Schlosser G. A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis. BMC Biol. 2018 Jul 16;16(1):79. doi: 10.1186/s12915-018-0540-5. |
Elesclomol restores mitochondrial function in genetic models of copper deficiency
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Citation:
Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23 Epub:
Not Epub Abstract:
Copper is an essential cofactor of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Soma S, Latimer AJ, Chun H, Vicary AC, Timbalia SA, Boulet A, Rahn JJ, Chan SSL, Leary SC, Kim BE, Gitlin JD, Gohil VM. Elesclomol restores mitochondrial function in genetic models of copper deficiency. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8161-8166. doi: 10.1073/pnas.1806296115. Epub 2018 Jul 23. |