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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats
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Citation:
Biol Phych. 2018;[Epub ahead of print] doi:10.1016/j.biopsych.2018.07.022 Epub:
Yes Abstract:
Background: The orexin system is important for reward-driven motivation but has not been implicated in the expression of a... Delivery Method:
injection Organism or Cell Type:
Rattus (rat) Citation Extract: James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G. Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats. Biol Phych. 2018;[Epub ahead of print] doi:10.1016/j.biopsych.2018.07.022. |
YAP/TAZ-TEAD Activity Links Mechanical Cues To Specific Cell Fate Within The Hindbrain Boundaries
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Citation:
bioRXive. 2018;[Epub] doi:10.1101/366351 Epub:
Yes Abstract:
How embryonic cells perceive their microenvironment through physical/mechanical cues during morphogenesis remains largely... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Voltes A, Hevia CF, Dingare C, Calzolari S, Terriente J, Norden C, Lecaudey V, Pujades C. YAP/TAZ-TEAD Activity Links Mechanical Cues To Specific Cell Fate Within The Hindbrain Boundaries. bioRXive. 2018;[Epub] doi:10.1101/366351. |
CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions
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Citation:
Angiogenesis. 2019 Feb;22(1):75-93. doi: 10.1007/s10456-018-9638-1. Epub 2018 Aug 10. PMID: 30097810; PMCID: PMC6510885 Epub:
Yes Abstract:
Vascular endothelial (VE) cadherin is a key component of endothelial adherens junctions (AJs) and plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chrifi I, Louzao-Martinez L, Brandt MM, van Dijk CGM, Bürgisser PE, Zhu C, Kros JM, Verhaar MC, Duncker DJ, Cheng C. CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions. Angiogenesis. 2019 Feb;22(1):75-93. doi: 10.1007/s10456-018-9638-1. Epub 2018 Aug 10. PMID: 30097810; PMCID: PMC6510885. |
Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish
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Citation:
Biol Open. 2018 Aug 10. pii: bio.035576. doi: 10.1242/bio.035576. [Epub ahead of print] Epub:
Yes Abstract:
Hemogen is a vertebrate transcription factor that performs important functions in erythropoiesis and testicular development and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Peters MJ, Parker SK, Grim J, Allard CAH, Levin J, Detrich HW 3rd. Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish. Biol Open. 2018 Aug 10. pii: bio.035576. doi: 10.1242/bio.035576. [Epub ahead of print]. |
A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors
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Citation:
Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17 Epub:
Not Epub Abstract:
Ewing's sarcoma treatment failures are associated with high mortality indicating a need for new therapeutic approaches. We... Delivery Method:
fatty acid conjugate & Endo-Porter Organism or Cell Type:
cell culture: TC-32 & CHLA-10 EFT lines and HEK293 renal epithelial control cells Citation Extract: Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL. A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors. Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17. |
Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes
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Citation:
Aging Dis. 2018 Aug 1;9(4):623-633. doi: 10.14336/AD.2017.0901. eCollection 2018 Aug Epub:
Not Epub Abstract:
Kif4a, a member of the kinesin superfamily, has been reported to participate in a series of cellular processes such as... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Tang F, Pan MH, Lu Y, Wan X, Zhang Y, Sun SC. Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes. Aging Dis. 2018 Aug 1;9(4):623-633. doi: 10.14336/AD.2017.0901. eCollection 2018 Aug. |
Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development
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Citation:
Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x Epub:
Not Epub Abstract:
As effectors of the Hippo signaling cascade, YAP1 and TAZ are transcriptional regulators playing important roles in development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Astone M, Lai JKH, Dupont S, Stainier DYR, Argenton F, Vettori A. Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x. |
Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS
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Citation:
Mol Ther Nucleic Acids. 2018;12:420-432. doi:10.1016/j.omtn.2018.05.019 Epub:
Not Epub Abstract:
DNA variants of the proteolipid protein 1 gene (PLP1) that shift PLP1/DM20 alternative splicing away from the PLP1 form toward... Delivery Method:
Endo-Porter, i.c.v. injection Organism or Cell Type:
cell culture: Oli-neu (immortalized oligodendrocyte precursor), mice Citation Extract: Tantzer S, Sperle K, Kenaley K, Taube J, Hobson GM. Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS. Mol Ther Nucleic Acids. 2018;12:420-432. doi:10.1016/j.omtn.2018.05.019. |
RES complex is associated with intron definition and required for zebrafish early embryogenesis
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Citation:
PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul Epub:
Not Epub Abstract:
Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ. RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul. |
Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration
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Citation:
Elife. 2018 Jun 28;7. pii: e34880. doi: 10.7554/eLife.34880 Epub:
Not Epub Abstract:
Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Collins MM, Maischein HM, Dufourcq P, Charpentier M, Blader P, Stainier DY. Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration. Elife. 2018 Jun 28;7. pii: e34880. doi: 10.7554/eLife.34880. |