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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Detection of unique Ebola virus oligonucleotides using fluorescently-labeled phosphorodiamidate morpholino oligonucleotide probe pairs

Authors:
Xiong Y, McQuistan TJ, Stanek JW, Summerton JE, Mata JE, Squier TC
Citation:
Anal Biochem. 2018 Sep 15;557:84-90. doi: 10.1016/j.ab.2018.07.006. Epub 2018 Jul 18. PMID: 30030994
Epub:
Not Epub
Abstract:
Here we identify a low-cost diagnostic platform using fluorescently-labeled phosphorodiamidate morpholino oligonucleotide (PMO...
Citation Extract:
Xiong Y, McQuistan TJ, Stanek JW, Summerton JE, Mata JE, Squier TC. Detection of unique Ebola virus oligonucleotides using fluorescently-labeled phosphorodiamidate morpholino oligonucleotide probe pairs. Anal Biochem. 2018 Sep 15;557:84-90. doi: 10.1016/j.ab.2018.07.006. Epub 2018 Jul 18. PMID: 30030994.

Generation and Validation of a Complete Knockout Model of abcc6a In Zebrafish

Authors:
Van Gils M, Willaert A, De Vilder EYG, Coucke P, Vanakker OM
Citation:
J Invest Dermatol. 2018 Jul 17. pii: S0022-202X(18)32326-1. doi: 10.1016/j.jid.2018.06.183. [Epub ahead of print]
Epub:
Yes
Abstract:
Pseudoxanthoma elasticum is an ectopic mineralization disease due to biallelic ABCC6 mutations. As no treatment options are...
Organism or Cell Type:
zebrafish
Citation Extract:
Van Gils M, Willaert A, De Vilder EYG, Coucke P, Vanakker OM. Generation and Validation of a Complete Knockout Model of abcc6a In Zebrafish. J Invest Dermatol. 2018 Jul 17. pii: S0022-202X(18)32326-1. doi: 10.1016/j.jid.2018.06.183. [Epub ahead of print].

Investigating the Role of G Protein βγ in Kv7-Dependent Relaxations of the Rat Vasculature

Authors:
Stott JB, Barrese V, Suresh M, Masoodi S, Greenwood IA
Citation:
Arterioscler Thromb Vasc Biol. 2018 Jul 12. pii: ATVBAHA.118.311360. doi: 10.1161/ATVBAHA.118.311360. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: In renal arteries, inhibitors of G protein βγ subunits (Gβγ) reduce Kv7 activity and inhibit Kv7-dependent receptor-...
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: rat dissected renal artery, mesenteric artery and cerebral artery
Citation Extract:
Stott JB, Barrese V, Suresh M, Masoodi S, Greenwood IA. Investigating the Role of G Protein βγ in Kv7-Dependent Relaxations of the Rat Vasculature. Arterioscler Thromb Vasc Biol. 2018 Jul 12. pii: ATVBAHA.118.311360. doi: 10.1161/ATVBAHA.118.311360. [Epub ahead of print].

Polarity and morphogenesis of the eye epithelium requires the adhesion junction associated adaptor protein Traf4

Authors:
Hehr CL, Halabi R, McFarlane S
Citation:
Cell Adh Migr. 2018 Jul 31:1-14. doi: 10.1080/19336918.2018.1477900. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During development, neuroepithelial progenitors acquire apico-basal polarity and adhere to one another via apically located...
Organism or Cell Type:
zebrafish
Citation Extract:
Hehr CL, Halabi R, McFarlane S. Polarity and morphogenesis of the eye epithelium requires the adhesion junction associated adaptor protein Traf4. Cell Adh Migr. 2018 Jul 31:1-14. doi: 10.1080/19336918.2018.1477900. [Epub ahead of print].

Alternative splicing of (ppp1r12a/mypt1) in zebrafish produces a novel myosin phosphatase targeting subunit

Authors:
LaFlamme A, Young KE, Lang I, Weiser DC
Citation:
Gene. 2018 Jun 27. pii: S0378-1119(18)30753-4. doi: 10.1016/j.gene.2018.06.092. [Epub ahead of print]
Epub:
Yes
Abstract:
Myosin phosphatase is an evolutionarily conserved regulator of actomyosin contractility, comprised of a regulatory subunit (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
LaFlamme A, Young KE, Lang I, Weiser DC. Alternative splicing of (ppp1r12a/mypt1) in zebrafish produces a novel myosin phosphatase targeting subunit. Gene. 2018 Jun 27. pii: S0378-1119(18)30753-4. doi: 10.1016/j.gene.2018.06.092. [Epub ahead of print].

Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function

Authors:
Chitramuthu BP, Bennett HPJ
Citation:
Methods Mol Biol. 2018;1806:207-231. doi: 10.1007/978-1-4939-8559-3_15
Epub:
Not Epub
Abstract:
The zebrafish (Danio rerio), a small tropical fish, has become a powerful model for the study of early vertebrate development,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chitramuthu BP, Bennett HPJ. Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function. Methods Mol Biol. 2018;1806:207-231. doi: 10.1007/978-1-4939-8559-3_15.

Effect of Tim23 Knockdown in vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPRmt in Muscle

Authors:
Oliveira AN, Hood DA
Citation:
Am J Physiol Cell Physiol. 2018 Jun 27. doi: 10.1152/ajpcell.00275.2017. [Epub ahead of print]
Epub:
Yes
Abstract:
The mitochondrial unfolded protein response (UPRmt) is a protein quality control mechanism that strives to achieve proteostasis...
Delivery Method:
Vivo-Morpholino
Citation Extract:
Oliveira AN, Hood DA. Effect of Tim23 Knockdown in vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPRmt in Muscle. Am J Physiol Cell Physiol. 2018 Jun 27. doi: 10.1152/ajpcell.00275.2017. [Epub ahead of print].

Cxcl12a induces snail1b expression to initiate collective migration and sequential Fgf-dependent neuromast formation in the zebrafish posterior lateral line primordium

Authors:
Neelathi UM, Dalle Nogare D, Chitnis AB
Citation:
Development. 2018 Jul 30;145(14). pii: dev162453. doi: 10.1242/dev.162453
Epub:
Not Epub
Abstract:
The zebrafish posterior lateral line primordium migrates along a path defined by the chemokine Cxcl12a, periodically depositing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Neelathi UM, Dalle Nogare D, Chitnis AB. Cxcl12a induces snail1b expression to initiate collective migration and sequential Fgf-dependent neuromast formation in the zebrafish posterior lateral line primordium. Development. 2018 Jul 30;145(14). pii: dev162453. doi: 10.1242/dev.162453.

FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy

Authors:
McMillin M, Grant S, Frampton G, Petrescu AD, Kain J, Williams E, Haines R, Canady L, DeMorrow S
Citation:
Cell Mol Gastroenterol Hepatol. 2018 Mar 6;6(1):47-63. doi: 10.1016/j.jcmgh.2018.02.008. eCollection 2018
Epub:
Not Epub
Abstract:
Background & Aims: Hepatic encephalopathy is a serious neurologic complication of acute and chronic liver diseases. We...
Delivery Method:
Vivo-Morpholino & Endo-Porter, Alzet pump
Organism or Cell Type:
C57Bl/6 mice
Citation Extract:
McMillin M, Grant S, Frampton G, Petrescu AD, Kain J, Williams E, Haines R, Canady L, DeMorrow S. FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy. Cell Mol Gastroenterol Hepatol. 2018 Mar 6;6(1):47-63. doi: 10.1016/j.jcmgh.2018.02.008. eCollection 2018.

Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression

Authors:
Moreno RL, Williams K, Jones KL, Ribera AB
Citation:
PLoS One. 2018 Jun 21;13(6):e0199233. doi: 10.1371/journal.pone.0199233. eCollection 2018
Epub:
Not Epub
Abstract:
Zebrafish primary motor neurons differ from each other with respect to morphology, muscle targets and electrophysiological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moreno RL, Williams K, Jones KL, Ribera AB. Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression. PLoS One. 2018 Jun 21;13(6):e0199233. doi: 10.1371/journal.pone.0199233. eCollection 2018.

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