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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
miR-133 mediated regulation of the hedgehog pathway orchestrates embryo myogenesis
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Citation:
Development. 2018 May 25. pii: dev.159657. doi: 10.1242/dev.159657. [Epub ahead of print] Epub:
Yes Abstract:
Skeletal myogenesis serves as a paradigm to investigate the molecular mechanisms underlying exquisitely regulated cell fate... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Mok GF, Lozano-Velasco E, Maniou E, Viaut C, Moxon S, Wheeler G, Münsterberg A. miR-133 mediated regulation of the hedgehog pathway orchestrates embryo myogenesis. Development. 2018 May 25. pii: dev.159657. doi: 10.1242/dev.159657. [Epub ahead of print]. |
Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals
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Citation:
BioRxiv. 2018. doi:10.1101/306803 Epub:
Not Epub Abstract:
The ability of cells to respond to intercellular signals, and the repertoire of possible responses to those signals, is defined... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals. BioRxiv. 2018. doi:10.1101/306803 . |
Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish
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Citation:
bioRxiv. 2018. doi:10.1101/308221 Epub:
Not Epub Abstract:
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN. Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish. bioRxiv. 2018. doi:10.1101/308221. |
Japanese Encephalitis Virus Infected Microglial Cells Secrete Exosomes Containing let-7a/b that Facilitate Neuronal Damage via Caspase Activation
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Citation:
bioRxiv. 2018. doi:10.1101/324715 Epub:
Not Epub Abstract:
Extracellular microRNAs (miRNAs) are essential for the cell to cell communication in the healthy and diseased brain. MicroRNAs... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
BALB/c mice pups Citation Extract: Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A. Japanese Encephalitis Virus Infected Microglial Cells Secrete Exosomes Containing let-7a/b that Facilitate Neuronal Damage via Caspase Activation. bioRxiv. 2018. doi:10.1101/324715. |
Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells
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Citation:
Sci Rep. 2018 May 18;8(1):7856. doi: 10.1038/s41598-018-26110-3 Epub:
Not Epub Abstract:
Sarcomeric signaling complexes are important to sustain proper sarcomere structure and function, however, the mechanisms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hsieh FC, Lu YF, Liau I, Chen CC, Cheng CM, Hsiao CD, Hwang SL. Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells. Sci Rep. 2018 May 18;8(1):7856. doi: 10.1038/s41598-018-26110-3. |
Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides
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Citation:
Org Prep Proc Int. 2018;50(3):332-42. doi:10.1080/00304948.2018.1462063 Epub:
Not Epub Abstract:
No abstract available. Citation Extract: Vohtancev IP, Sherstyuk YV, Silnikov VN, Abramova TV. Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides. Org Prep Proc Int. 2018;50(3):332-42. doi:10.1080/00304948.2018.1462063. |
Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation
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Citation:
Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29 Epub:
Not Epub Abstract:
BACKGROUND: The buccopharyngeal membrane is a thin layer of cells covering the embryonic mouth. The perforation of this... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Houssin NS, Bharathan NK, Turner SD, Dickinson AJ. Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation. Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29. |
Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening
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Citation:
PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018 Epub:
Not Epub Abstract:
Splice-switching oligonucleotides (SSOs) that can modulate RNA splicing are used for the treatment of many genetic disorders.... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: RD Citation Extract: Shimo T, Tachibana K, Obika S. Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening. PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018. |
Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain
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Citation:
Development. 2018 May 15;145(10). pii: dev161034. doi: 10.1242/dev.161034 Epub:
Not Epub Abstract:
Neural stem cells (NSCs) in the adult vertebrate brain are found in a quiescent state and can preserve long-lasting progenitor... Delivery Method:
intracerebroventricular injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Than-Trong E, Ortica-Gatti S, Mella S, Nepal C, Alunni A, Bally-Cuif L. Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain. Development. 2018 May 15;145(10). pii: dev161034. doi: 10.1242/dev.161034. |
Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry
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Citation:
Nat Commun. 2018 May 16;9(1):1942. doi: 10.1038/s41467-018-04284-8 Epub:
Not Epub Abstract:
The establishment of left-right (LR) asymmetry is fundamental to animal development, but the identification of a unifying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Juan T, Géminard C, Coutelis JB, Cerezo D, Polès S, Noselli S, Fürthauer M. Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry. Nat Commun. 2018 May 16;9(1):1942. doi: 10.1038/s41467-018-04284-8. |