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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish
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Citation:
Sci Rep. 2016 Nov 28;6:37660. doi: 10.1038/srep37660 Epub:
Not Epub Abstract:
Mutations in Pantothenate kinase 2 and Coenzyme A (CoA) synthase (COASY), genes involved in CoA biosynthesis, are associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Khatri D, Zizioli D, Tiso N, Facchinello N, Vezzoli S, Gianoncelli A, Memo M, Monti E, Borsani G, Finazzi D. Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish. Sci Rep. 2016 Nov 28;6:37660. doi: 10.1038/srep37660. |
The expression of chemorepulsive guidance receptors and the regenerative abilities of spinal-projecting neurons after spinal cord injury
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Citation:
Neuroscience. 2016 Nov 24. pii: S0306-4522(16)30641-8. doi: 10.1016/j.neuroscience.2016.11.020. [Epub ahead of print] Epub:
Not Epub Abstract:
Spinal cord injury (SCI) in mammals leads to permanent loss of function because axons do not regenerate in the central nervous... Organism or Cell Type:
lamprey Citation Extract: Chen J, Laramore C, Shifman MI. The expression of chemorepulsive guidance receptors and the regenerative abilities of spinal-projecting neurons after spinal cord injury. Neuroscience. 2016 Nov 24. pii: S0306-4522(16)30641-8. doi: 10.1016/j.neuroscience.2016.11.020. [Epub ahead of print]. |
Functional validation of ABHD12 mutations in the neurodegenerative disease PHARC
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Citation:
Neurobiol Dis. 2016 Nov 23. pii: S0969-9961(16)30267-4. doi: 10.1016/j.nbd.2016.11.008. [Epub ahead of print] Epub:
Yes Abstract:
BHD12 mutations have been linked to neurodegenerative PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tingaud-Sequeira A, Raldúa D, Lavie J, Mathieu G, Bordier M, Knoll-Gellida A, Rambeau P, Coupry I, André M, Malm E, Möller C, Andreasson S, Rendtorff ND, Tranebjærg L, Koenig M, Lacombe D, Goizet C, Babin PJ. Functional validation of ABHD12 mutations in the neurodegenerative disease PHARC. Neurobiol Dis. 2016 Nov 23. pii: S0969-9961(16)30267-4. doi: 10.1016/j.nbd.2016.11.008. [Epub ahead of print]. |
The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury
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Citation:
Neurobiol Dis. 2016 Nov 22. pii: S0969-9961(16)30264-9. doi: 10.1016/j.nbd.2016.11.006. [Epub ahead of print] Epub:
Yes Abstract:
Paralysis following spinal cord injury (SCI) is due to interruption of axons and their failure to regenerate. It has been... Delivery Method:
injection Organism or Cell Type:
sea lamprey Citation Extract: Hu J, Zhang G, Rodemer W, Jin LQ, Shifman M, Selzer ME. The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury. Neurobiol Dis. 2016 Nov 22. pii: S0969-9961(16)30264-9. doi: 10.1016/j.nbd.2016.11.006. [Epub ahead of print]. |
Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide
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Citation:
Molecules. 2016 Nov 22;21(11). pii: E1582 Epub:
Not Epub Abstract:
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-... Delivery Method:
Lipofectin Organism or Cell Type:
cultured cells: Immortalised mdx myoblasts (H2K cells) Citation Extract: Chen S, Le BT, Rahimizadeh K, Shaikh K, Mohal N, Veedu RN. Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide. Molecules. 2016 Nov 22;21(11). pii: E1582. |
MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae
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Citation:
BMC Genomics. 2016 Nov 15;17(1):922 Epub:
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BACKGROUND: MicroRNAs (miRNAs) are critical regulators responding to acute environmental stresses in both plants and animals.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hung IC, Hsiao YC, Sun HS, Chen TM, Lee SJ. MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae. BMC Genomics. 2016 Nov 15;17(1):922. |
The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis
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Citation:
Sci Rep. 2016 Nov 14;6:36994. doi: 10.1038/srep36994 Epub:
Not Epub Abstract:
Mouse oocytes respond to DNA damage by arresting in meiosis I through activity of the Spindle Assembly Checkpoint (SAC) and DNA... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Hamdan M, Jones KT, Cheong Y, Lane SI. The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis. Sci Rep. 2016 Nov 14;6:36994. doi: 10.1038/srep36994. |
Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry
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Citation:
J Am Chem Soc. 2016;[Epub ahead of print] doi:10.1021/jacs.6b08854 Epub:
Yes Abstract:
Phosphorodiamidate morpholinos (PMOs) and PMO-DNA chimeras have been prepared on DNA synthesizers using phosphoramidite... Citation Extract: Paul S, Caruthers MH. Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry. J Am Chem Soc. 2016;[Epub ahead of print] doi:10.1021/jacs.6b08854. |
In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine conceptuses retards their development via abrogation of MAPK and MTOR pathways
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Citation:
J Animal Sci. 2016;94(supp 5):376 Epub:
Not Epub Abstract:
Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW. In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Ovis aries (sheep) conceptus Citation Extract: Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW. In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine conceptuses retards their development via abrogation of MAPK and MTOR pathways. J Animal Sci. 2016;94(supp 5):376. |
Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy
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Citation:
Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.127. [Epub ahead of print] Epub:
Yes Abstract:
Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Vila MC, Rayavarapu S, Hogarth MW, Van der Meulen JH, Horn A, Defour A, Takeda S, Brown KJ, Hathout Y, Nagaraju K, Jaiswal JK. Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy. Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.127. [Epub ahead of print]. |