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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Effects of NDRG1 family proteins on photoreceptor outer segment morphology in zebrafish

Authors:
Takita S, Wada Y, Kawamura S
Citation:
Sci Rep. 2016 Nov 4;6:36590. doi: 10.1038/srep36590
Epub:
Not Epub
Abstract:
Rods and cones are functionally and morphologically distinct. We previously identified N-myc downstream-regulated gene 1b (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takita S, Wada Y, Kawamura S. Effects of NDRG1 family proteins on photoreceptor outer segment morphology in zebrafish. Sci Rep. 2016 Nov 4;6:36590. doi: 10.1038/srep36590.

Identification of novel genes and networks governing hematopoietic stem cell development

Authors:
Han T, Yang CS, Chang KY, Zhang D, Imam FB, Rana TM
Citation:
EMBO Rep. 2016 Oct 26. pii: e201642395. [Epub ahead of print]
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) are capable of giving rise to all blood cell lineages throughout adulthood, and the generation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han T, Yang CS, Chang KY, Zhang D, Imam FB, Rana TM. Identification of novel genes and networks governing hematopoietic stem cell development. EMBO Rep. 2016 Oct 26. pii: e201642395. [Epub ahead of print].

Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca

Authors:
Nichols JT, Blanco-Sánchez B, Brooks EP, Parthasarathy R, Dowd J, Subramanian A, Nachtrab G, Poss KD, Schilling TF, Kimmel CB
Citation:
Development. 2016 Oct 27. pii: dev.141036. [Epub ahead of print]
Epub:
Yes
Abstract:
Heightened phenotypic variation among mutant animals is a well-known, but poorly understood phenomenon. One hypothetical...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nichols JT, Blanco-Sánchez B, Brooks EP, Parthasarathy R, Dowd J, Subramanian A, Nachtrab G, Poss KD, Schilling TF, Kimmel CB. Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca. Development. 2016 Oct 27. pii: dev.141036. [Epub ahead of print].

A Nuclear Role for miR-9 and Argonaute Proteins in Balancing Quiescent and Activated Neural Stem Cell States

Authors:
Katz S, Cussigh D, Urbán N, Blomfield I, Guillemot F, Bally-Cuif L, Coolen M
Citation:
Cell Rep. 2016 Oct 25;17(5):1383-1398. doi: 10.1016/j.celrep.2016.09.088
Epub:
Not Epub
Abstract:
Throughout life, adult neural stem cells (NSCs) produce new neurons and glia that contribute to crucial brain functions....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Katz S, Cussigh D, Urbán N, Blomfield I, Guillemot F, Bally-Cuif L, Coolen M. A Nuclear Role for miR-9 and Argonaute Proteins in Balancing Quiescent and Activated Neural Stem Cell States. Cell Rep. 2016 Oct 25;17(5):1383-1398. doi: 10.1016/j.celrep.2016.09.088.

Microcephaly, intractable seizures and developmental delay caused by biallelic variants in TBCD: Further delineation of a new chaperone-mediated tubulinopathy

Authors:
Pode-Shakked B, Barash H, Ziv L, Gripp KW, Flex E, Barel O, Carvalho KS, Scavina M, Chillemi G, Niceta M, Eyal E, Kol N, Ben-Zeev B, Bar-Yosef O, Marek-Yagel D, Bertini E, Duker AL, Anikster Y, Tartaglia M, Raas-Rothschild A
Citation:
Clin Genet. 2016 Nov 2. doi: 10.1111/cge.12914. [Epub ahead of print]
Epub:
Yes
Abstract:
Microtubule dynamics play a crucial role in neuronal development and function, and several neurodevelopmental disorders have...
Organism or Cell Type:
zebrafish
Citation Extract:
Pode-Shakked B, Barash H, Ziv L, Gripp KW, Flex E, Barel O, Carvalho KS, Scavina M, Chillemi G, Niceta M, Eyal E, Kol N, Ben-Zeev B, Bar-Yosef O, Marek-Yagel D, Bertini E, Duker AL, Anikster Y, Tartaglia M, Raas-Rothschild A. Microcephaly, intractable seizures and developmental delay caused by biallelic variants in TBCD: Further delineation of a new chaperone-mediated tubulinopathy. Clin Genet. 2016 Nov 2. doi: 10.1111/cge.12914. [Epub ahead of print].

IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain

Authors:
Bhattarai P, Thomas AK, Cosacak MI, Papadimitriou C, Mashkaryan V, Froc C, Reinhardt S, Kurth T, Dahl A, Zhang Y, Kizil C
Citation:
Cell Rep. 2016 Oct 18;17(4):941-948. doi: 10.1016/j.celrep.2016.09.075
Epub:
Not Epub
Abstract:
Human brains are prone to neurodegeneration, given that endogenous neural stem/progenitor cells (NSPCs) fail to support...
Delivery Method:
icv (cerebroventricular) injection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattarai P, Thomas AK, Cosacak MI, Papadimitriou C, Mashkaryan V, Froc C, Reinhardt S, Kurth T, Dahl A, Zhang Y, Kizil C. IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. Cell Rep. 2016 Oct 18;17(4):941-948. doi: 10.1016/j.celrep.2016.09.075.

Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis

Authors:
Kari W, Zeng F, Zitzelsberger L, Will J, Rothbächer U
Citation:
J Vis Exp. 2016 Oct 16;(116). doi: 10.3791/54313
Epub:
Not Epub
Abstract:
Simple model organisms are instrumental for in vivo studies of developmental and cellular differentiation processes. Currently...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Kari W, Zeng F, Zitzelsberger L, Will J, Rothbächer U. Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis. J Vis Exp. 2016 Oct 16;(116). doi: 10.3791/54313.

miR-19b Regulates Ventricular Action Potential Duration in Zebrafish

Authors:
Benz A, Kossack M, Auth D, Seyler C, Zitron E, Juergensen L, Katus HA, Hassel D
Citation:
Sci Rep. 2016 Nov 2;6:36033. doi: 10.1038/srep36033
Epub:
Not Epub
Abstract:
Sudden cardiac death due to ventricular arrhythmias often caused by action potential duration (APD) prolongation is a common...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Benz A, Kossack M, Auth D, Seyler C, Zitron E, Juergensen L, Katus HA, Hassel D. miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. Sci Rep. 2016 Nov 2;6:36033. doi: 10.1038/srep36033.

Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia

Authors:
Hennessey KM, Smith TR, Xu JW, Alas GC, Ojo KK, Merritt EA, Paredez AR
Citation:
PLoS Negl Trop Dis. 2016 Nov 2;10(11):e0005107. doi: 10.1371/journal.pntd.0005107
Epub:
Not Epub
Abstract:
Giardiasis is widely acknowledged to be a neglected disease in need of new therapeutics to address toxicity and resistance...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Hennessey KM, Smith TR, Xu JW, Alas GC, Ojo KK, Merritt EA, Paredez AR. Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia. PLoS Negl Trop Dis. 2016 Nov 2;10(11):e0005107. doi: 10.1371/journal.pntd.0005107.

Functional antagonism of alpha-subunits of Kv channel in developing brain ventricular system

Authors:
Shen H, Bocksteins E, Kondrychyn I, Snyders D, Korzh V
Citation:
Development. 2016 Oct 11. pii: dev.140467. [Epub ahead of print]
Epub:
Yes
Abstract:
The brain ventricular system is essential for neurogenesis and brain homeostasis. Its neuroepithelial lining effects these...
Organism or Cell Type:
zebrafish
Citation Extract:
Shen H, Bocksteins E, Kondrychyn I, Snyders D, Korzh V. Functional antagonism of alpha-subunits of Kv channel in developing brain ventricular system. Development. 2016 Oct 11. pii: dev.140467. [Epub ahead of print].

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