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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource

Authors:
Shim H, Kim JH, Kim CY, Hwang S, Kim H, Yang S, Lee JE, Lee I
Citation:
Nucl Acid Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw897
Epub:
Yes
Abstract:
Whole exome sequencing (WES) accelerates disease gene discovery using rare genetic variants, but further statistical and...
Link:
http://nar.oxfordjournals.org/content/early/2016/10/05/nar.gkw897.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shim H, Kim JH, Kim CY, Hwang S, Kim H, Yang S, Lee JE, Lee I. Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource. Nucl Acid Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw897.

Survival Motor Neuron (SMN) protein is required for normal mouse liver development

Authors:
Szunyogova E, Zhou H, Maxwell GK, Powis RA, Muntoni F, Gillingwater TH, Parson SH
Citation:
Sci Rep. 2016;6:34635. doi:10.1038/srep34635
Epub:
Not Epub
Abstract:
Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of...
Link:
http://www.nature.com/articles/srep34635
Delivery Method:
injection
Organism or Cell Type:
SMA mice
Citation Extract:
Szunyogova E, Zhou H, Maxwell GK, Powis RA, Muntoni F, Gillingwater TH, Parson SH. Survival Motor Neuron (SMN) protein is required for normal mouse liver development. Sci Rep. 2016;6:34635. doi:10.1038/srep34635.

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production

Authors:
Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE
Citation:
Cell Rep. 2016;17:458-468. doi:10.1016/j.celrep.2016.09.012
Epub:
Not Epub
Abstract:
Vitamin D insufficiency is a worldwide epidemic affecting billions of individuals, including pregnant women and children....
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(16)31217-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE. Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production. Cell Rep. 2016;17:458-468. doi:10.1016/j.celrep.2016.09.012.

EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus

Authors:
Wang X, Sun J, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2016 Sep 27. pii: S0006-291X(16)31612-6. doi: 10.1016/j.bbrc.2016.09.138
Epub:
Yes
Abstract:
Eph receptor tyrosine kinases (RTKs) and their ephrin ligands play multiple roles in the developing nervous system, including...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16316126
Organism or Cell Type:
Xenopus
Citation Extract:
Wang X, Sun J, Li C, Mao B. EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus. Biochem Biophys Res Commun. 2016 Sep 27. pii: S0006-291X(16)31612-6. doi: 10.1016/j.bbrc.2016.09.138.

Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development

Authors:
Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R
Citation:
PLoS ONE. 2012;7(6): e39714. doi:10.1371/journal.pone.0039714
Epub:
Not Epub
Abstract:
Kif26b, a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. Kif26b expression is...
Link:
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0039714
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse kidney explant
Citation Extract:
Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R. Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development. PLoS ONE. 2012;7(6): e39714. doi:10.1371/journal.pone.0039714.

Quantitative imaging reveals real-time Pou5f3-Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish

Authors:
Perez-Camps M, Tian J, Chng SC, Sem KP, Sudhaharan T, Teh C, Wachsmuth M, Korzh V, Ahmed S, Reversade B
Citation:
Elife. 2016 Sep 29;5. pii: e11475. doi: 10.7554/eLife.11475
Epub:
Not Epub
Abstract:
Formation of the three embryonic germ layers is a fundamental developmental process that initiates differentiation. How the...
Link:
https://elifesciences.org/content/5/e11475
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Perez-Camps M, Tian J, Chng SC, Sem KP, Sudhaharan T, Teh C, Wachsmuth M, Korzh V, Ahmed S, Reversade B. Quantitative imaging reveals real-time Pou5f3-Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish. Elife. 2016 Sep 29;5. pii: e11475. doi: 10.7554/eLife.11475.

Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish

Authors:
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K
Citation:
Physiol Rep. 2016 Oct;4(19). pii: e12940. doi: 10.14814/phy2.12940
Epub:
Not Epub
Abstract:
A volume-regulated anion channel (VRAC) has been electrophysiologically characterized in innumerable mammalian cell types. VRAC...
Link:
http://physreports.physiology.org/content/4/19/e12940.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K. Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish. Physiol Rep. 2016 Oct;4(19). pii: e12940. doi: 10.14814/phy2.12940.

Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia

Authors:
Sedykh I, TeSlaa JJ, Tatarsky RL, Keller AN, Toops KA, Lakkaraju A, Nyholm MK, Wolman MA, Grinblat Y
Citation:
Sci Rep. 2016;6:34437. doi:10.1038/srep34437
Epub:
Not Epub
Abstract:
Cilia are cell surface organelles with key roles in a range of cellular processes, including generation of fluid flow by motile...
Link:
http://www.nature.com/articles/srep34437
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sedykh I, TeSlaa JJ, Tatarsky RL, Keller AN, Toops KA, Lakkaraju A, Nyholm MK, Wolman MA, Grinblat Y. Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia. Sci Rep. 2016;6:34437. doi:10.1038/srep34437.

Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos

Authors:
Molina-Villa T, Mendoza V, López-Casillas F
Citation:
J Vis Exp. 2016 Aug 31;(114). doi: 10.3791/54405
Epub:
Not Epub
Abstract:
By combining the powers of Affinity Labeling and Immunoprecipitation (AFLIP), a technique for the detection of low abundance...
Link:
http://www.jove.com/video/54405/affinity-labeling-detection-endogenous-receptors-from-zebrafish
Organism or Cell Type:
zebrafish
Citation Extract:
Molina-Villa T, Mendoza V, López-Casillas F. Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos. J Vis Exp. 2016 Aug 31;(114). doi: 10.3791/54405.

Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I

Authors:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X
Citation:
Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130. [Epub ahead of print]
Epub:
Yes
Abstract:
Dentin dysplasia type I (DDI) is an autosomal-dominant genetic disorder resulting from dentin defects. The molecular basis of...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/humu.23130/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X. Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I. Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130. [Epub ahead of print].

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