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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Chromosome 5q33 deletions associated with congenital heart defects

Authors:
Starkovich M, Lalani SR, Mercer CL, Scott DA
Citation:
Am J Med Genet A. 2016 Sep 2. doi: 10.1002/ajmg.a.37957. [Epub ahead of print]
Epub:
Yes
Abstract:
Congenital heart defects (CHD) are present in over 1% of all newborns and are the leading cause of birth-defect-related deaths...
Organism or Cell Type:
zebrafish
Citation Extract:
Starkovich M, Lalani SR, Mercer CL, Scott DA. Chromosome 5q33 deletions associated with congenital heart defects. Am J Med Genet A. 2016 Sep 2. doi: 10.1002/ajmg.a.37957. [Epub ahead of print].

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia

Authors:
del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK
Citation:
Dev Cell. 2016;[Epub ahead of print]. doi:10.1016/j.devcel.2016.08.002
Epub:
Yes
Abstract:
Human genomics is identifying candidate genes for congenital heart disease (CHD), but discovering the underlying mechanisms...
Organism or Cell Type:
zebrafish
Citation Extract:
del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK. Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia. Dev Cell. 2016;[Epub ahead of print]. doi:10.1016/j.devcel.2016.08.002.

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Authors:
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Changh CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.
Citation:
Proc Natl Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1600204113
Epub:
Yes
Abstract:
Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine...
Organism or Cell Type:
zebrafish
Citation Extract:
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Changh CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proc Natl Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1600204113.

Morphology and Gene Expression Screening with Morpholinos in Zebrafish Embryos

Authors:
Tseng LC, Tang CH, Jiang YJ
Citation:
Methods Mol Biol. 2016;1470:213-24. doi: 10.1007/978-1-4939-6337-9_17
Epub:
Not Epub
Abstract:
High-throughput screening with a loss-of-function strategy is a logical and efficient way to identify novel genes involved in...
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng LC, Tang CH, Jiang YJ. Morphology and Gene Expression Screening with Morpholinos in Zebrafish Embryos. Methods Mol Biol. 2016;1470:213-24. doi: 10.1007/978-1-4939-6337-9_17.

Identification of p53-target genes in Danio rerio

Authors:
Mandriani B, Castellana S, Rinaldi C, Manzoni M, Venuto S, Rodriguez-Aznar E, Galceran J, Nieto MA, Borsani G, Monti E, Mazza T, Merla G, Micale L
Citation:
Sci Rep. 2016;6:32474. doi:10.1038/srep32474
Epub:
Not Epub
Abstract:
To orchestrate the genomic response to cellular stress signals, p53 recognizes and binds to DNA containing specific and well-...
Organism or Cell Type:
zebrafish
Citation Extract:
Mandriani B, Castellana S, Rinaldi C, Manzoni M, Venuto S, Rodriguez-Aznar E, Galceran J, Nieto MA, Borsani G, Monti E, Mazza T, Merla G, Micale L. Identification of p53-target genes in Danio rerio. Sci Rep. 2016;6:32474. doi:10.1038/srep32474.

Role of morphine, miR-212/132 and mu opioid receptor in the regulation of Bdnf in zebrafish embryos

Authors:
Jimenez-Gonzalez A, García-Concejo A, López-Benito S, Gonzalez-Nunez V, Arévalo JC, Rodriguez RE
Citation:
Biochim Biophys Acta. 2016 Jun;1860(6):1308-16. doi: 10.1016/j.bbagen.2016.03.001. Epub 2016 Mar 4
Epub:
Not Epub
Abstract:
BACKGROUND: Morphine is one of the first-line therapies for the treatment of pain despite its secondary effects. It modifies...
Organism or Cell Type:
zebrafish
Citation Extract:
Jimenez-Gonzalez A, García-Concejo A, López-Benito S, Gonzalez-Nunez V, Arévalo JC, Rodriguez RE. Role of morphine, miR-212/132 and mu opioid receptor in the regulation of Bdnf in zebrafish embryos. Biochim Biophys Acta. 2016 Jun;1860(6):1308-16. doi: 10.1016/j.bbagen.2016.03.001. Epub 2016 Mar 4.

Lxr regulates lipid metabolic and visual perception pathways during zebrafish development

Authors:
Pinto CL, Kalasekar SM, McCollum CW, Riu A, Jonsson P, Lopez J, Swindell EC, Bouhlatouf A, Balaguer P, Bondesson M, Gustafsson JÅ
Citation:
Mol Cell Endocrinol. 2016 Jan 5;419:29-43. doi: 10.1016/j.mce.2015.09.030. Epub 2015 Sep 30
Epub:
Not Epub
Abstract:
The Liver X Receptors (LXRs) play important roles in multiple metabolic pathways, including fatty acid, cholesterol,...
Organism or Cell Type:
zebrafish
Citation Extract:
Pinto CL, Kalasekar SM, McCollum CW, Riu A, Jonsson P, Lopez J, Swindell EC, Bouhlatouf A, Balaguer P, Bondesson M, Gustafsson JÅ. Lxr regulates lipid metabolic and visual perception pathways during zebrafish development. Mol Cell Endocrinol. 2016 Jan 5;419:29-43. doi: 10.1016/j.mce.2015.09.030. Epub 2015 Sep 30.

Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin

Authors:
Warner JF, Miranda EL, McClay DR
Citation:
Dev Biol. 2016 Mar 15;411(2):314-24. doi: 10.1016/j.ydbio.2016.02.008. Epub 2016 Feb 9
Epub:
Not Epub
Abstract:
Most bilaterians exhibit a left-right asymmetric distribution of their internal organs. The sea urchin larva is notable in this...
Organism or Cell Type:
sea urchin
Citation Extract:
Warner JF, Miranda EL, McClay DR. Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin. Dev Biol. 2016 Mar 15;411(2):314-24. doi: 10.1016/j.ydbio.2016.02.008. Epub 2016 Feb 9.

The positive transcriptional elongation factor (P-TEFb) is required for neural crest specification

Authors:
Hatch VL, Marin-Barba M, Moxon S, Ford CT, Ward NJ, Tomlinson ML, Desanlis I, Hendry AE, Hontelez S, van Kruijsbergen I, Veenstra GJ, Münsterberg AE, Wheeler GN
Citation:
Dev Biol. 2016 Aug 15;416(2):361-72. doi: 10.1016/j.ydbio.2016.06.012. Epub 2016 Jun 23
Epub:
Not Epub
Abstract:
Regulation of gene expression at the level of transcriptional elongation has been shown to be important in stem cells and...
Organism or Cell Type:
Xenopus
Citation Extract:
Hatch VL, Marin-Barba M, Moxon S, Ford CT, Ward NJ, Tomlinson ML, Desanlis I, Hendry AE, Hontelez S, van Kruijsbergen I, Veenstra GJ, Münsterberg AE, Wheeler GN. The positive transcriptional elongation factor (P-TEFb) is required for neural crest specification. Dev Biol. 2016 Aug 15;416(2):361-72. doi: 10.1016/j.ydbio.2016.06.012. Epub 2016 Jun 23.

Characterization of the zebrafish cx36.7 gene promoter: Its regulation of cardiac-specific expression and skeletal muscle-specific repression

Authors:
Miyagi H, Nag K, Sultana N, Munakata K, Hirose S, Nakamura N
Citation:
Gene. 2016 Feb 15;577(2):265-74. doi: 10.1016/j.gene.2015.12.013. Epub 2015 Dec 9
Epub:
Not Epub
Abstract:
Zebrafish connexin 36.7 (cx36.7/ecx) has been identified as a key molecule in the early stages of heart development in this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyagi H, Nag K, Sultana N, Munakata K, Hirose S, Nakamura N. Characterization of the zebrafish cx36.7 gene promoter: Its regulation of cardiac-specific expression and skeletal muscle-specific repression. Gene. 2016 Feb 15;577(2):265-74. doi: 10.1016/j.gene.2015.12.013. Epub 2015 Dec 9.

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