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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
Who is the best surrogate for germ stem cell transplantation in fish?
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Citation:
Aquaculture, Volume 549, 2022, 737759, ISSN 0044-8486, https://doi.org/10.1016/j.aquaculture.2021.737759 Epub:
Not Epub Abstract:
Surrogate broodstock technology in fishes has potential for aquaculture as well as endangered species conservation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička. Who is the best surrogate for germ stem cell transplantation in fish?. Aquaculture, Volume 549, 2022, 737759, ISSN 0044-8486, https://doi.org/10.1016/j.aquaculture.2021.737759. |
Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development
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Citation:
PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698 Epub:
Not Epub Abstract:
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuil LE, MacKenzie KC, Tang CS, Windster JD, Le TL, Karim A, de Graaf BM, van der Helm R, van Bever Y, Sloots CEJ, Meeussen C, Tibboel D, de Klein A, Wijnen RMH, Amiel J, Lyonnet S, Garcia-Barcelo M-M, Tam PKH, Alves MM, Brooks AS, Hofstra RMW, Brosens E. Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development. PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698. |
Deep learning to design nuclear-targeting abiotic miniproteins
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Citation:
Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3 Epub:
Not Epub Abstract:
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space... Delivery Method:
protein-linked Organism or Cell Type:
cell culture Citation Extract: Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep learning to design nuclear-targeting abiotic miniproteins. Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3. |
Neuron Navigator 3 (NAV3) is Required for Heart Development
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Citation:
Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-734749/v1 Epub:
Not Epub Abstract:
Background: As a tightly controlled biological process, cardiogenesis requires the specification and migration of a suite of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lv F, Yuan F, Lu X, Ge X, Shi L, Wang X, Liu D, Chen C. Neuron Navigator 3 (NAV3) is Required for Heart Development. Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-734749/v1. |
Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury
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Citation:
Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print Epub:
Yes Abstract:
In strong contrast to limited repair within the mammalian central nervous system, the spinal cord of adult zebrafish is capable... Organism or Cell Type:
zebrafish Citation Extract: Cui C, Wang LF, Huang SB, Zhao P, Chen YQ, Wu YB, Qiao CM, Zhao WJ, Shen YQ. Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury. Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print. |
Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish
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Citation:
PLoS Genet. 2021;17(8):e1009693. doi:10.1371/journal.pgen.1009693 Epub:
Not Epub Abstract:
The ubiquitin-proteasome system plays important roles in various biological processes as it degrades the majority of cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gao S, Wang Z, Wang L, Wang H, Yuan H, Liu X, Chen S, Chen Z, de Thé H, Zhang W, Zhang Y, Zhu J, Zhou J. Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish. PLoS Genet. 2021;17(8):e1009693. doi:10.1371/journal.pgen.1009693. |
Open-Label Evaluation of Eteplirsen in Patients with Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping: PROMOVI Trial
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Citation:
J Neuromuscul Dis. 2021 Jun 8;[Epub ahead of print]. doi:10.3233/JND-210643 Epub:
Yes Abstract:
Background: Eteplirsen received accelerated FDA approval for treatment of Duchenne muscular dystrophy (DMD) with mutations... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: McDonald CM, Shieh PB, Abdel-Hamid HZ, Connolly AM, Ciafaloni E, Wagner KR, Goemans N, Mercuri E, Khan N, Koenig E, Malhotra J, Zhang W, Han B, Mendell JR, the Italian DMD Telethon Registry Study Group, Leuven NMRC Registry Investigators, CINRG Duchenne Natural History Investigators, and PROMOVI Trial Clinical Investigators. Open-Label Evaluation of Eteplirsen in Patients with Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping: PROMOVI Trial. J Neuromuscul Dis. 2021 Jun 8;[Epub ahead of print]. doi:10.3233/JND-210643. |
Splice-Modulating Oligonucleotide QR-110 Restores CEP290 mRNA and Function in Human c.2991+1655A>G LCA10 Models
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Citation:
Mol Ther Nucleic Acids. 2018 Sep 7;12:730-740. doi: 10.1016/j.omtn.2018.07.010. Epub 2018 Jul 23. PMID: 30114557; PMCID: PMC6092551 Epub:
Not Epub Abstract:
Leber congenital amaurosis type 10 (LCA10) is a severe inherited retinal dystrophy associated with mutations in CEP290. The... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human retinal organoids Citation Extract: Dulla K, Aguila M, Lane A, Jovanovic K, Parfitt DA, Schulkens I, Chan HL, Schmidt I, Beumer W, Vorthoren L, Collin RWJ, Garanto A, Duijkers L, Brugulat-Panes A, Semo M, Vugler AA, Biasutto P, Adamson P, Cheetham ME. Splice-Modulating Oligonucleotide QR-110 Restores CEP290 mRNA and Function in Human c.2991+1655A>G LCA10 Models. Mol Ther Nucleic Acids. 2018 Sep 7;12:730-740. doi: 10.1016/j.omtn.2018.07.010. Epub 2018 Jul 23. PMID: 30114557; PMCID: PMC6092551. |
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis
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Citation:
Proc Nat Acad Sci. 2021;118(32):e2015528118. doi:10.1073/pnas.2015528118 Epub:
Not Epub Abstract:
Dyskeratosis congenita (DC) is a rare inherited bone marrow failure and cancer predisposition syndrome caused by mutations in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: García-Castillo J, Alcaraz-Pérez F, Martínez-Balsalobre E, García-Moreno D, Rossmann MP, Fernández-Lajarín M, Bernabé-García M, Pérez-Oliva AB, Rodríguez-Cortez VC, Clara Bueno C, Adatto I, Agarwal S, Menéndez P, Zon LI, Mulero V, Cayuela ML. Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis. Proc Nat Acad Sci. 2021;118(32):e2015528118. doi:10.1073/pnas.2015528118. |
Identification of de novo EP300 and PLAU variants in a patient with Rubinstein-Taybi syndrome-related arterial vasculopathy and skeletal anomaly
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Citation:
Sci Rep. 2021;11(1):15931. doi:0.1038/s41598-021-95133-0 Epub:
Not Epub Abstract:
Rubinstein-Taybi syndrome (RSTS) is a human genetic disorder characterized by distinctive craniofacial features, broad thumbs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Park JE, Kim E, Lee D-W, Park TK, Kim MS, Jang SY, Ahn J, Park KB, Kim K-H, Park H-C, Ki C-S, Kim D-K. Identification of de novo EP300 and PLAU variants in a patient with Rubinstein-Taybi syndrome-related arterial vasculopathy and skeletal anomaly. Sci Rep. 2021;11(1):15931. doi:0.1038/s41598-021-95133-0. |