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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations
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Citation:
Elife. 2021 May 20;10:e62155. doi: 10.7554/eLife.62155. Online ahead of print Epub:
Not Epub Abstract:
Mosaic inactivation of CCM2 in humans causes cerebral cavernous malformations (CCMs) containing adjacent dilated blood-filled... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 May 20;10:e62155. doi: 10.7554/eLife.62155. Online ahead of print. |
Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism
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Citation:
Endocrinology. 2021 May 21:bqab101. doi: 10.1210/endocr/bqab101. Online ahead of print Epub:
Yes Abstract:
Congenital hypothyroidism (CH) is a highly prevalent but treatable neonatal endocrine disorder. Thyroid dyshormonogenesis is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun F, Fang Y, Zhang MM, Zhang RJ, Wu FY, Yang RM, Tu PH, Dong M, Zhao SX, Song HD. Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism. Endocrinology. 2021 May 21:bqab101. doi: 10.1210/endocr/bqab101. Online ahead of print. |
Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models
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Citation:
Bone. 2022 Feb;155:116263. doi: 10.1016/j.bone.2021.116263. Epub 2021 Nov 23. PMID: 34826632; PMCID: PMC9007314 Epub:
Not Epub Abstract:
Many key signaling molecules used to build tissues during embryonic development are re-activated at injury sites to stimulate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heller IS, Guenther CA, Meireles AM, Talbot WS, Kingsley DM. Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models. Bone. 2022 Feb;155:116263. doi: 10.1016/j.bone.2021.116263. Epub 2021 Nov 23. PMID: 34826632; PMCID: PMC9007314. |
Interferon tau: Influences on growth and development of the conceptus
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Citation:
Theriogenology. 2020;150:75-83. doi:10.1016/j.theriogenology.2020.01.069 Epub:
Not Epub Abstract:
Interferon tau (IFNT), the pregnancy recognition signal secreted from trophectoderm cells of ruminant conceptuses abrogates the... Organism or Cell Type:
Ovis aries (sheep) conceptus Citation Extract: Bazer FW, Seo H, Wu G, Johnson GA. Interferon tau: Influences on growth and development of the conceptus. Theriogenology. 2020;150:75-83. doi:10.1016/j.theriogenology.2020.01.069. |
The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
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Citation:
Cells. 2021;10(5):1233. doi:10.3390/cells10051233 Epub:
Not Epub Abstract:
SMYD3 (SET and MYND domain containing protein 3) is a methylase over-expressed in cancer cells and involved in oncogenesis.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fittipaldi R, Floris P, Proserpio V, Cotelli F, Beltrame M, Caretti G. The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development. Cells. 2021;10(5):1233. doi:10.3390/cells10051233 . |
A newly identified Rab-GDI paralogue has a role in neural development in amphibia
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Citation:
Gene. 2017 Jan 30;599:78-86. doi: 10.1016/j.gene.2016.11.013. Epub 2016 Nov 9 Epub:
Not Epub Abstract:
Vesicle shuttling is critical for many cellular and organismal processes, including embryonic development. GDI proteins... Organism or Cell Type:
Xenopus Citation Extract: Nazlamova L, Noble A, Schubert FR, McGeehan J, Myers F, Guille M, Scarlett G. A newly identified Rab-GDI paralogue has a role in neural development in amphibia. Gene. 2017 Jan 30;599:78-86. doi: 10.1016/j.gene.2016.11.013. Epub 2016 Nov 9. |
Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation
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Citation:
Sci Adv. 2021 May 14;7(20):eabg2099. doi: 10.1126/sciadv.abg2099. Print 2021 May Epub:
Not Epub Abstract:
The four-pass transmembrane proteins Vangl1 and Vangl2 are dedicated core components of Wnt/planar cell polarity (Wnt/PCP)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Feng D, Wang J, Yang W, Li J, Lin X, Zha F, Wang X, Ma L, Choi NT, Mii Y, Takada S, Huen MSY, Guo Y, Zhang L, Gao B. Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation. Sci Adv. 2021 May 14;7(20):eabg2099. doi: 10.1126/sciadv.abg2099. Print 2021 May. |
Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control
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Citation:
EMBO J. 2022 Mar 1;41(5):e109256. doi: 10.15252/embj.2021109256. Epub 2022 Jan 18. PMID: 35040509; PMCID: PMC8886528 Epub:
Not Epub Abstract:
The control of mRNA stability plays a central role in regulating gene expression patterns. Recent studies have revealed that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mishima Y, Han P, Ishibashi K, Kimura S, Iwasaki S. Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control. EMBO J. 2022 Mar 1;41(5):e109256. doi: 10.15252/embj.2021109256. Epub 2022 Jan 18. PMID: 35040509; PMCID: PMC8886528. |
The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis
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Citation:
Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2109022118. doi: 10.1073/pnas.2109022118. PMID: 34903650; PMCID: PMC8713801 Epub:
Not Epub Abstract:
In mammals, cyclic dinucleotides (CDNs) bind and activate STING to initiate an antiviral type I interferon response. CDNs and... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (anemone) Citation Extract: Margolis SR, Dietzen PA, Hayes BM, Wilson SC, Remick BC, Chou S, Vance RE. The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2109022118. doi: 10.1073/pnas.2109022118. PMID: 34903650; PMCID: PMC8713801. |
Slit2 is necessary for optic axon organization in the zebrafish ventral midline
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Citation:
Cells Dev. 2021 Apr 10;166:203677. doi: 10.1016/j.cdev.2021.203677. Online ahead of print Epub:
Not Epub Abstract:
Slit-Robo signaling has been implicated in regulating several steps of retinal ganglion cell axon guidance, with a central role... Organism or Cell Type:
zebrafish Citation Extract: Davison C, Zolessi FR. Slit2 is necessary for optic axon organization in the zebrafish ventral midline. Cells Dev. 2021 Apr 10;166:203677. doi: 10.1016/j.cdev.2021.203677. Online ahead of print. |