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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12221 scientific papers returned from the database with the search filters currently being used below.

Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia

Authors:
Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M
Citation:
Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029
Epub:
Yes
Abstract:
Our recent data show the valuable potential of TnP for the development of a new and safe anti-inflammatory drug due to its...
Link:
https://www.sciencedirect.com/science/article/pii/S1050464821001194
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M. Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia. Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029.

Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression

Authors:
Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P
Citation:
J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print
Epub:
Yes
Abstract:
Background: Coagulation factor IX (FIX) is a serine protease zymogen involved in the intrinsic blood coagulation pathway, and...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/jth.15365
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P. Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression. J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print.

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus

Authors:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y
Citation:
Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118
Epub:
Not Epub
Abstract:
Fibroblast growth factor (FGF)/extracellular signal-regulated kinase (ERK) signaling plays a crucial role in anterior–posterior...
Link:
https://www.pnas.org/content/118/20/e2100342118
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118.

RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus

Authors:
Kim H, Jang S
Citation:
Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print
Epub:
Yes
Abstract:
N6-methyladenosine (m6A) is the most prevalent internal RNA modification, and has a widespread impact on mRNA stability and...
Link:
https://mcb.asm.org/content/early/2021/05/04/MCB.00104-21
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H, Jang S. RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus. Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print.

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia

Authors:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J
Citation:
Brain. 2021;[Epub] doi:10.1093/brain/awab041
Epub:
Not Epub
Abstract:
Human 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) is a putative iron-containing non-heme oxygenase of unknown specificity...
Link:
https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab041/6273093
Organism or Cell Type:
zebrafish
Citation Extract:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J. Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia. Brain. 2021;[Epub] doi:10.1093/brain/awab041.

Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo

Authors:
Molina MD, Lepage T
Citation:
Curr Top Dev Biol. 2020;140:283-316. doi: 10.1016/bs.ctdb.2019.10.007. Epub 2019 Nov 22
Epub:
Not Epub
Abstract:
Specification of the main axes of polarity of the embryo is an essential process during embryonic development. In many species...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0070215319300821
Organism or Cell Type:
sea urchin
Citation Extract:
Molina MD, Lepage T. Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo. Curr Top Dev Biol. 2020;140:283-316. doi: 10.1016/bs.ctdb.2019.10.007. Epub 2019 Nov 22.

Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate

Authors:
Chuykin I, Itoh K, Kim K, Sokol SY
Citation:
J Cell Sci. 2021 Dec 15;134(24):jcs258864. doi: 10.1242/jcs.258864. Epub 2021 Dec 15. PMID: 34806749; PMCID: PMC8729781
Epub:
Not Epub
Abstract:
The orientation of epithelial cells in the plane of the tissue, known as planar cell polarity (PCP), is regulated by...
Link:
https://journals.biologists.com/jcs/article/134/24/jcs258864/273708/Frizzled3-inhibits-Vangl2-Prickle3-association-to
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chuykin I, Itoh K, Kim K, Sokol SY. Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate. J Cell Sci. 2021 Dec 15;134(24):jcs258864. doi: 10.1242/jcs.258864. Epub 2021 Dec 15. PMID: 34806749; PMCID: PMC8729781.

Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish

Authors:
Hung J-C, Wu J-L, Hong J-R
Citation:
Int J Mol Sci. 2021;22:4832. doi:10.3390/ijms22094832
Epub:
Not Epub
Abstract:
The BH3-only molecule Bad regulates cell death via its differential protein phosphorylation, but very few studies address its...
Link:
https://www.mdpi.com/1422-0067/22/9/4832
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung J-C, Wu J-L, Hong J-R. Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish. Int J Mol Sci. 2021;22:4832. doi:10.3390/ijms22094832.

Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception

Authors:
Boutillon A, Escot S, Elouin A, Jahn D, González-Tirado S, Starruß J, Brusch L, David NB
Citation:
Dev Cell. 2022 Jun 20;57(12):1529-1544.e5. doi: 10.1016/j.devcel.2022.05.001. Epub 2022 May 24. PMID: 35613615
Epub:
Not Epub
Abstract:
Morphogenesis, wound healing, and some cancer metastases depend upon the migration of cell collectives that need to be guided...
Link:
https://www.cell.com/developmental-cell/fulltext/S1534-5807(22)00329-X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boutillon A, Escot S, Elouin A, Jahn D, González-Tirado S, Starruß J, Brusch L, David NB. Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception. Dev Cell. 2022 Jun 20;57(12):1529-1544.e5. doi: 10.1016/j.devcel.2022.05.001. Epub 2022 May 24. PMID: 35613615.

Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway

Authors:
Wang H, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H
Citation:
Development. 2021 Apr 28:dev.199441. doi: 10.1242/dev.199441. Online ahead of print
Epub:
Yes
Abstract:
The focal adhesion protein Kindlin2 is essential for integrin activation, a process that is fundamental to cell-extracellular...
Link:
https://journals.biologists.com/dev/article/doi/10.1242/dev.199441/261719/Kindlin2-regulates-neural-crest-specification-via
Organism or Cell Type:
Xenopus
Citation Extract:
Wang H, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H. Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. Development. 2021 Apr 28:dev.199441. doi: 10.1242/dev.199441. Online ahead of print.

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