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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish
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Citation:
Cells. 2021 Jan 22;10(2):221. doi: 10.3390/cells10020221 Epub:
Not Epub Abstract:
The "distal axonopathy" hypothesis in amyotrophic lateral sclerosis (ALS) proposes that pathological changes occur at... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Campanari ML, Marian A, Ciura S, Kabashi E. TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish. Cells. 2021 Jan 22;10(2):221. doi: 10.3390/cells10020221. |
The Axenfeld–Rieger Syndrome Gene FOXC1 Contributes to Left–Right Patterning
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Citation:
Genes. 2021;12(2):170. https://doi.org/10.3390/genes12020170 Epub:
Not Epub Abstract:
Precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm establishes the left–right... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ. The Axenfeld–Rieger Syndrome Gene FOXC1 Contributes to Left–Right Patterning. Genes. 2021;12(2):170. https://doi.org/10.3390/genes12020170 . |
CDK19-related disorder results from both loss-of-function and gain-of-function de novo missense variants
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Citation:
Genet Med. 2021;[Epub ahead of print] doi:10.1038/s41436-020-01091-9 Epub:
Yes Abstract:
Purpose: To expand the recent description of a new neurodevelopmental syndrome related to alterations in CDK19.
Methods:... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zarate YA, Uehara T, Abe K, Oginuma M, Harako S, Ishitani S, Lehesjoki A-E, Bierhals T, Kloth K, Ehmke N, Horn D, Holtgrewe M, Anderson K, Viskochil D, Edgar-Zarate CL, Sacoto MJG, Schnur RE, Morrow MM, Sanchez-Valle A, Pappas J, Rabin R, Muona M, Anttonen A-K, Platzer K, Luppe J, Gburek-Augustat J, Kaname T, Okamoto N, Mizuno S, Kaido Yusaku, Ohkuma Y, Hirose Y, Ishitani T, Kosaki K. CDK19-related disorder results from both loss-of-function and gain-of-function de novo missense variants. Genet Med. 2021;[Epub ahead of print] doi:10.1038/s41436-020-01091-9. |
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds
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Citation:
Development. 2021;148:dev1905008 doi:10.1242/dev.195008 Epub:
Yes Abstract:
Pathogenic mutations in the endocytic receptor LRP2 in humans are associated with severe neural tube closure defects (NTDs)... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Goerne J, Wallingford JB, Hammes-Lewin A, Feistel K. Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds. Development. 2021;148:dev1905008 doi:10.1242/dev.195008. |
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience
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Citation:
Neuron. 2021;[Epub ahead of print] doi:10.1016/j.neuron.2021.01.002 Epub:
Yes Abstract:
Gene Ontology analyses of autism spectrum disorders (ASD) risk genes have repeatedly highlighted synaptic function and... Organism or Cell Type:
Xenopus tropicalis Citation Extract: Willsey HR, Exner CRT, Xu Y, Everitt A, Sun N, Wang B, Dea J, Schmunk G, Zaltsman Y, Teerikorpi N, Kim A, Anderson AS, Shin D, Seyler M, Nowakowski TJ, Harland RM, Willsey AJ, State MW. Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience. Neuron. 2021;[Epub ahead of print] doi:10.1016/j.neuron.2021.01.002. |
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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Citation:
Cell. 2021;184:[Epub ahead of print] doi:10.1016/j.cell.2020.12.024 Epub:
Yes Abstract:
Ras GTPase-activating protein-binding proteins 1 and 2 (G3BP1 and G3BP2, respectively) are widely recognized as core components... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Prentzell MT, Rehbein U, Sandoval MC, De Meulemeester A-S, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G, Genomics England Research Consortium, de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Pittol JMR, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell. 2021;184:[Epub ahead of print] doi:10.1016/j.cell.2020.12.024. |
Anterior lateral plate mesoderm gives rise to multiple tissues and requires tbx5a function in left-right asymmetry, migration dynamics, and cell specification of late-addition cardiac cells
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Citation:
Dev Biol. 2021;472:52-66. doi:10.1016/j.ydbio.2021.01.007 Epub:
Not Epub Abstract:
In this study, we elucidate a single cell resolution fate map in the zebrafish in a sub-section of the anterior Lateral Plate... Organism or Cell Type:
zebrafish Citation Extract: Mao LMF, Boyle Anderson EAT, Ho RK. Anterior lateral plate mesoderm gives rise to multiple tissues and requires tbx5a function in left-right asymmetry, migration dynamics, and cell specification of late-addition cardiac cells. Dev Biol. 2021;472:52-66. doi:10.1016/j.ydbio.2021.01.007. |
Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus
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Citation:
Dev Biol. 2021 Jan 20:S0012-1606(20)30322-5. doi:10.1016/j.ydbio.2020.12.012. Online ahead of print Epub:
Yes Abstract:
Coup-TF, a member of the nuclear receptor super-family, is present in the pool of maternal mRNAs and proteins in the sea urchin... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Tsironis I, Paganos P, Gouvi G, Tsimpos P, Stamopoulou A, Arnone MI, Flytzanis CN. Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus. Dev Biol. 2021 Jan 20:S0012-1606(20)30322-5. doi:10.1016/j.ydbio.2020.12.012. Online ahead of print. |
Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish
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Citation:
Cell Mol Neurobiol. 2021 Jan 22. doi:10.1007/s10571-020-01022-x. Online ahead of print Epub:
Not Epub Abstract:
Insulin-like growth factor-1 (IGF-1) is a neurotrophic factor produced locally in the central nervous system which can promote... Delivery Method:
lesion site Organism or Cell Type:
zebrafish Citation Extract: Zhao L, Zhang B, Huang S, Zhou Z, Jia X, Qiao C, Wang F, Sun M, Shi Y, Yao L, Cui C, Shen Y. Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish. Cell Mol Neurobiol. 2021 Jan 22. doi:10.1007/s10571-020-01022-x. Online ahead of print. |
Diversified Biomineralization Roles of Pteria penguin Pearl Shell Lectins as Matrix Proteins
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Citation:
Int J Mol Sci. 2021;22(3),1081. doi:10.3390/ijms22031081 Epub:
Not Epub Abstract:
Previously, we isolated jacalin-related lectins termed PPL2, PPL3 (PPL3A, 3B and 3C) and PPL4 from the mantle secretory fluid... Delivery Method:
Endo-Porter Organism or Cell Type:
Pteria penguin (oyster) Citation Extract: Ogawa T, Sato R, Naganuma T, Liu K, Sato S, Sakaue S, Osada M, Yoshimi K, Muramoto K. Diversified Biomineralization Roles of Pteria penguin Pearl Shell Lectins as Matrix Proteins. Int J Mol Sci. 2021;22(3),1081. doi:10.3390/ijms22031081. |
