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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
Function of Sox2 in ependymal cells of lesioned spinal cords in adult zebrafish
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Citation:
Neurosci Res. 2014 Nov;88:84-7. doi: 10.1016/j.neures.2014.07.010. Epub 2014 Aug 20 Epub:
Not Epub Abstract:
The sex-determining region Y-box 2 (Sox2) is related not only to pluripotency, but also to cell proliferation. Zebrafish can... Organism or Cell Type:
zebrafish Citation Extract: Ogai K, Nakatani K, Hisano S, Sugitani K, Koriyama Y, Kato S. Function of Sox2 in ependymal cells of lesioned spinal cords in adult zebrafish. Neurosci Res. 2014 Nov;88:84-7. doi: 10.1016/j.neures.2014.07.010. Epub 2014 Aug 20. |
Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation
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Citation:
Development. 2014 Sep;141(17):3363-9. doi: 10.1242/dev.106864. Epub 2014 Jul 30 Epub:
Not Epub Abstract:
In vertebrates that have been examined to date, the sexual identity of germ cells is determined by the sex of gonadal somatic... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Nishimura T, Herpin A, Kimura T, Hara I, Kawasaki T, Nakamura S, Yamamoto Y, Saito TL, Yoshimura J, Morishita S, Tsukahara T, Kobayashi S, Naruse K, Shigenobu S, Sakai N, Schartl M, Tanaka M. Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation. Development. 2014 Sep;141(17):3363-9. doi: 10.1242/dev.106864. Epub 2014 Jul 30. |
Molecular characterization of SLC24A5 variants and evaluation of Nitisinone treatment efficacy in a zebrafish model of OCA6
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Citation:
Pigment Cell Melanoma Res. 2020 Apr 9. doi: 10.1111/pcmr.12879. [Epub ahead of print] Epub:
Yes Abstract:
Skin pigmentation is a highly heterogeneous trait with diverse consequences worldwide. SLC24A5, encoding a potent K+ -dependent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yousaf S, Sethna S, Chaudhary MA, Shaikh RS, Riazuddin S, Ahmed ZM. Molecular characterization of SLC24A5 variants and evaluation of Nitisinone treatment efficacy in a zebrafish model of OCA6. Pigment Cell Melanoma Res. 2020 Apr 9. doi: 10.1111/pcmr.12879. [Epub ahead of print]. |
Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization
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Citation:
J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print] Epub:
Not Epub Abstract:
Reciprocal changes in histone lysine methylation/demethylation of M(LPS + IFN-γ)/M(IL-10) genes is one of the factors that... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Parmar N, Chandrakar P, Kar S. Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization. J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print]. |
Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling
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Citation:
PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696 Epub:
Not Epub Abstract:
It is well known that various developmental signals play diverse roles in hematopoietic stem and progenitor cell (HSPC)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heng J, Lv P, Zhang Y, Cheng X, Wang L, Ma D, Liu F. Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling. PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696. |
Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B
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Citation:
PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690 Epub:
Not Epub Abstract:
Loss-of-function mutations in the human coagulation factor 9 (F9) gene lead to hemophilia B. Here, we dissected the... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Krooss S, Werwitzke S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B. PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690. |
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I
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Citation:
Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969 Epub:
Not Epub Abstract:
During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation.... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou C, Miao Y, Cui Z, ShiYang X, Zhang Y, Xiong B. The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I. Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969. |
Piezo1 and outflow tract and aortic valve development
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Citation:
J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013 Epub:
Yes Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 and outflow tract and aortic valve development. J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013. |
Trade-off between somatic and germline repair in a vertebrate supports the expensive germ line hypothesis
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Citation:
Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201918205. doi: 10.1073/pnas.1918205117. [Epub ahead of print] Epub:
Yes Abstract:
The disposable soma theory is a central tenet of the biology of aging where germline immortality comes at the cost of an aging... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen HY, Jolly C, Bublys K, Marcu D, Immler S. Trade-off between somatic and germline repair in a vertebrate supports the expensive germ line hypothesis. Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201918205. doi: 10.1073/pnas.1918205117. [Epub ahead of print]. |
Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling
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Citation:
Dev Biol. 2022 Jun;486:26-43. doi: 10.1016/j.ydbio.2022.03.006. Epub 2022 Mar 23. PMID: 35337795; PMCID: PMC11238767 Epub:
Not Epub Abstract:
The formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lange M, Ohnesorge N, Hoffmann D, Rocha SF, Benedito R, Siekmann AF. Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling. Dev Biol. 2022 Jun;486:26-43. doi: 10.1016/j.ydbio.2022.03.006. Epub 2022 Mar 23. PMID: 35337795; PMCID: PMC11238767. |