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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway
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Citation:
PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943 Epub:
Not Epub Abstract:
Pericellular and extracellular proteoglycans play an important role in modulating morphogen gradients and signal transductions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee Y-H, Kawakami K, HuangFu W-C, Liu I-H. Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway. PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943. |
Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish
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Citation:
Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print] Epub:
Yes Abstract:
IGF2BPs, a subclass of RNA-binding proteins, regulate cellular differentiation, proliferation and migration during multiple... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu J, Lu C, Ge S, Mei J, Li X, Guo W. Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish. Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print]. |
NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis
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Citation:
Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031 Epub:
Not Epub Abstract:
Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031. |
Golodirsen
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Citation:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27 Epub:
Not Epub Abstract:
Golodirsen is synthetic antisense oligonucleotide designed to cause skipping of abnormal exons in the synthesis of the... Citation Extract: The LiverTox team. Golodirsen. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27. |
Eteplirsen
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Citation:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27 Epub:
Not Epub Abstract:
Eteplirsen is synthetic antisense oligonucleotide designed to cause skipping of abnormal exons during synthesis of the... Citation Extract: The LiverTox team. Eteplirsen. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. 2020 Feb 27. |
EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus
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Citation:
Biochem Biophys Res Commun. 2020 Mar 25. pii: S0006-291X(20)30590-8. doi: 10.1016/j.bbrc.2020.03.099. [Epub ahead of print] Epub:
Yes Abstract:
Receptor tyrosine kinase EphA7 is specifically expressed in otic region in Xenopus early development. However, its role in... Organism or Cell Type:
Xenopus Citation Extract: Wang X, Sun J, Wang Z, Li C, Mao B. EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus. Biochem Biophys Res Commun. 2020 Mar 25. pii: S0006-291X(20)30590-8. doi: 10.1016/j.bbrc.2020.03.099. [Epub ahead of print]. |
Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis
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Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0489-9 Epub:
Yes Abstract:
During mouse embryonic development, pluripotent cells rapidly divide and diversify, yet the regulatory programs that define the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pijuan-Sala B, Wilson NK, Xia J, Hou X, Hannah RL, Kinston S, Calero-Nieto FJ, Olivier Poirion O, Preissl S, Liu F, Göttgens B. Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0489-9. |
RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells
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Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0493-0 Epub:
Yes Abstract:
The availability of nucleotides has a direct impact on transcription. The inhibition of dihydroorotate dehydrogenase (DHODH)... Organism or Cell Type:
zebrafish Citation Extract: Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Greig EC, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Brian J. Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-0493-0. |
Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis
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Citation:
J Cell Biol. 2020;219(4):[Epub ahead of print] doi:10.1083/jcb.201907213 Epub:
Yes Abstract:
In mitotic cells, DNA damage induces temporary G2 arrest via inhibitory Cdk1 phosphorylation. In contrast, fully grown G2-stage... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Subramanian GN, Greaney J, Wei Z, Becherel O, Lavin M, Homer HA. Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis. J Cell Biol. 2020;219(4):[Epub ahead of print] doi:10.1083/jcb.201907213. |
DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies
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Citation:
Hum Mol Genet. 2020 Oct 10;29(17):2855-2871. doi: 10.1093/hmg/ddaa173. PMID: 32766788; PMCID: PMC7566544 Epub:
Not Epub Abstract:
DOCK3 is a member of the DOCK family of guanine nucleotide exchange factors that regulate cell migration, fusion and viability... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reid AL, Wang Y, Samani A, Hightower RM, Lopez MA, Gilbert SR, Ianov L, Crossman DK, Dell'Italia LJ, Millay DP, van Groen T, Halade GV, Alexander MS. DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies. Hum Mol Genet. 2020 Oct 10;29(17):2855-2871. doi: 10.1093/hmg/ddaa173. PMID: 32766788; PMCID: PMC7566544. |
