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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
High-throughput custom capture sequencing identifies novel mutations in coloboma-associated genes: Mutation in DNA-binding domain of retinoic acid receptor beta affects nuclear localization causing ocular coloboma
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Citation:
Hum Mutat. 2019 Dec 9. doi: 10.1002/humu.23954. [Epub ahead of print] Epub:
Yes Abstract:
Uveal coloboma is a potentially blinding congenital ocular malformation caused by the failure of optic fissure closure during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kalaskar VK, Alur RP, Li LK, Thomas JW, Sergeev YV, Blain D, Hufnagel RB, Cogliati T, Brooks BP. High-throughput custom capture sequencing identifies novel mutations in coloboma-associated genes: Mutation in DNA-binding domain of retinoic acid receptor beta affects nuclear localization causing ocular coloboma. Hum Mutat. 2019 Dec 9. doi: 10.1002/humu.23954. [Epub ahead of print]. |
The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development
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Citation:
Hum Mol Genet. 2019 Dec 9. pii: ddz278. doi: 10.1093/hmg/ddz278. [Epub ahead of print] Epub:
Yes Abstract:
Mutations in the key transcription factor, SOX2, alone account for 20% of anophthalmia (no eye) and microphthalmia (small eye)... Organism or Cell Type:
zebrafish Citation Extract: Dash S, Brastrom LK, Patel SD, Scott CA, Slusarski DC, Lachke SA. The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development. Hum Mol Genet. 2019 Dec 9. pii: ddz278. doi: 10.1093/hmg/ddz278. [Epub ahead of print]. |
EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway
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Citation:
Hum Genomics. 2019 Dec 5;13(1):63. doi: 10.1186/s40246-019-0238-y Epub:
Not Epub Abstract:
BACKGROUND: Mandibulofacial dysostosis with microcephaly (MFDM) is characteristic of multiple skeletal anomalies comprising... Organism or Cell Type:
zebrafish Citation Extract: Wu J, Yang Y, He Y, Li Q, Wang X, Sun C, Wang L, An Y, Luo F. EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway. Hum Genomics. 2019 Dec 5;13(1):63. doi: 10.1186/s40246-019-0238-y. |
Glis3 as a critical regulator of thyroid primordium specification
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Citation:
Thyroid. 2019 Dec 4. doi: 10.1089/thy.2019.0196. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: GLIS3 (GLI-Similar protein 3) is a transcription factor involved in several cellular processes. Homozygous... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rurale G, Marelli F, Duminuco P, Persani L. Glis3 as a critical regulator of thyroid primordium specification. Thyroid. 2019 Dec 4. doi: 10.1089/thy.2019.0196. [Epub ahead of print]. |
Massive centriole production can occur in the absence of deuterosomes in multiciliated cells
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Citation:
Nat Cell Biol. 2019;21:1544–1552. doi: 10.1038/s41556-019-0427-x. Epub:
Not Epub Abstract:
Multiciliated cells (MCCs) amplify large numbers of centrioles that convert into basal bodies, which are required for producing... Organism or Cell Type:
cell culture: Xenopus epithelial cells Citation Extract: Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. Massive centriole production can occur in the absence of deuterosomes in multiciliated cells. Nat Cell Biol. 2019;21:1544–1552. doi: 10.1038/s41556-019-0427-x.. |
Synaptotagmin 1 regulates cortical granule exocytosis during mouse oocyte activation
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Citation:
Zygote. 2019 Dec 2:1-6. doi: 10.1017/S0967199419000704. [Epub ahead of print] Epub:
Yes Abstract:
Synaptotagmin 1 (Syt1) is an abundant and important presynaptic vesicle protein that binds Ca2+ for the regulation of synaptic... Organism or Cell Type:
mouse oocyte Citation Extract: Zhu XL, Li SF, Zhang XQ, Xu H, Luo YQ, Yi YH, Lv LJ, Zhang CH, Wang ZB, Ouyang YC, Hou Y, Schatten H, Liu FH. Synaptotagmin 1 regulates cortical granule exocytosis during mouse oocyte activation. Zygote. 2019 Dec 2:1-6. doi: 10.1017/S0967199419000704. [Epub ahead of print]. |
Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a
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Citation:
Sci Rep. 2019 Dec 2;9(1):18130. doi: 10.1038/s41598-019-54544-w Epub:
Not Epub Abstract:
In this study, to investigate the secondary function of Rpl10a in zebrafish development, morpholino antisense oligonucleotides... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W. Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a. Sci Rep. 2019 Dec 2;9(1):18130. doi: 10.1038/s41598-019-54544-w. |
Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary
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Citation:
Development. 2020 Jun 8;147(11):dev186882. doi: 10.1242/dev.186882. PMID: 32439756 Epub:
Not Epub Abstract:
The formation and maintenance of sharp boundaries between groups of cells play a vital role during embryonic development as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kesavan G, Machate A, Hans S, Brand M. Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary. Development. 2020 Jun 8;147(11):dev186882. doi: 10.1242/dev.186882. PMID: 32439756. |
Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization
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Citation:
Nucleic Acids Res. 2019 Nov 28. pii: gkz1117. doi: 10.1093/nar/gkz1117. [Epub ahead of print] Epub:
Not Epub Abstract:
The Spinal Muscular Atrophy (SMA) gene SMN was recently duplicated (SMN1 and SMN2) in higher primates. Furthermore, invasion of... Delivery Method:
cell scraping Organism or Cell Type:
cell culture: human SMA type-I fibroblasts GM03813 Citation Extract: Pagliarini V, Jolly A, Bielli P, Di Rosa V, De la Grange P, Sette C. Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization. Nucleic Acids Res. 2019 Nov 28. pii: gkz1117. doi: 10.1093/nar/gkz1117. [Epub ahead of print]. |
The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors
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Citation:
Development. 2019 Nov 29. pii: dev.180133. doi: 10.1242/dev.180133. [Epub ahead of print] Epub:
Yes Abstract:
Multipotent progenitor populations are necessary for generating diverse tissue types during embryogenesis. We show the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ. The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development. 2019 Nov 29. pii: dev.180133. doi: 10.1242/dev.180133. [Epub ahead of print]. |