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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish
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Citation:
Stem Cell Res Ther. 2019 Dec 16;10(1):389. doi: 10.1186/s13287-019-1495-3 Epub:
Not Epub Abstract:
OBJECTIVE: Neural tube defects (NTDs) are the most serious and common birth defects in the clinic. The SRY-related HMG box B1 (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Zhou W, Li X, Gao M, Ji S, Tian W, Ji G, Du J, Hao A. SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish. Stem Cell Res Ther. 2019 Dec 16;10(1):389. doi: 10.1186/s13287-019-1495-3. |
BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
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Citation:
Life Sci Alliance. 2020 Mar 4;3(4):e202000666. doi: 10.26508/lsa.202000666. PMID: 32132179; PMCID: PMC7063472 Epub:
Not Epub Abstract:
Angiogenesis and lymphangiogenesis are key processes during embryogenesis as well as under physiological and pathological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cohen B, Tempelhof H, Raz T, Oren R, Nicenboim J, Bochner F, Even R, Jelinski A, Eilam R, Ben-Dor S, Adaddi Y, Golani O, Lazar S, Yaniv K, Neeman M. BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression. Life Sci Alliance. 2020 Mar 4;3(4):e202000666. doi: 10.26508/lsa.202000666. PMID: 32132179; PMCID: PMC7063472. |
SCGN deficiency results in colitis susceptibility
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Citation:
Elife. 2019 Oct 30;8. pii: e49910. doi:10.7554/eLife.49910 Epub:
Not Epub Abstract:
Inflammatory bowel disease (IBD) affects 1.5-3.0 million people in the United States. IBD is genetically determined and many... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sifuentes-Dominguez LF, Li H, Llano E, Liu Z, Singla A, Patel AS, Kathania M, Khoury A, Norris N, Rios JJ, Starokadomskyy P, Park JY, Gopal P, Liu Q, Tan S, Chan L, Ross T, Harrison S, Venuprasad K, Baker LA, Jia D, Burstein E. SCGN deficiency results in colitis susceptibility. Elife. 2019 Oct 30;8. pii: e49910. doi:10.7554/eLife.49910. |
Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence
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Citation:
PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006 Epub:
Not Epub Abstract:
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006. |
Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation
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Citation:
eLife. 2019;8:e51447. doi:10.7554/eLife.51447 Epub:
Not Epub Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. eLife. 2019;8:e51447. doi:10.7554/eLife.51447. |
Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia
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Citation:
Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print] Epub:
Yes Abstract:
Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM. Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia. Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print]. |
AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos
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Citation:
Sci Total Environ. 2019 Nov 21:135097. doi: 10.1016/j.scitotenv.2019.135097. [Epub ahead of print] Epub:
Not Epub Abstract:
Recent studies have shown an association between maternal exposure to ambient fine particle matter (PM2.5) and congenital heart... Organism or Cell Type:
zebrafish Citation Extract: Ren F, Ji C, Huang Y, Aniagu S, Jiang Y, Chen T. AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos. Sci Total Environ. 2019 Nov 21:135097. doi: 10.1016/j.scitotenv.2019.135097. [Epub ahead of print]. |
Gene duplication and functional divergence of the zebrafish otospiralin genes
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Citation:
Dev Genes Evol. 2019 Dec 14. doi: 10.1007/s00427-019-00642-8. [Epub ahead of print] Epub:
Yes Abstract:
Otospiralin (OTOSP) is a small protein of unknown function, expressed in fibrocytes of the inner ear and required for normal... Organism or Cell Type:
zebrafish Citation Extract: Aissette B, Sepand R, Amal B, Masanari T, Vanessa G, Amal S, Tanja B, Olfa J, Uwe S, Saber M. Gene duplication and functional divergence of the zebrafish otospiralin genes. Dev Genes Evol. 2019 Dec 14. doi: 10.1007/s00427-019-00642-8. [Epub ahead of print]. |
Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9
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Citation:
Genome Res. 2019 Dec 12. doi: 10.1101/gr.248559.119. [Epub ahead of print] Epub:
Yes Abstract:
Genome editing by the well-established CRISPR/Cas9 technology has greatly facilitated our understanding of many biological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun Y, Zhang B, Luo L, Shi DL, Wang H, Cui Z, Huang H, Cao Y, Shu X, Zhang W, Zhou J, Li Y, Du J, Zhao Q, Chen J, Zhong H, Zhong TP, Li L, Xiong JW, Peng J, Xiao W, Zhang J, Yao J, Yin Z, Mo X, Peng G, Zhu J, Chen Y, Zhou Y, Liu D, Pan W, Zhang Y, Ruan H, Liu F, Zhu Z, Meng A; ZAKOC Consortium. Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome Res. 2019 Dec 12. doi: 10.1101/gr.248559.119. [Epub ahead of print]. |
Ectoderm to mesoderm transition by down-regulation of actomyosin contractility
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Citation:
PLoS Biol. 2021 Jan 6;19(1):e3001060. doi: 10.1371/journal.pbio.3001060. PMID: 33406067; PMCID: PMC7815211 Epub:
Not Epub Abstract:
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F. Ectoderm to mesoderm transition by down-regulation of actomyosin contractility. PLoS Biol. 2021 Jan 6;19(1):e3001060. doi: 10.1371/journal.pbio.3001060. PMID: 33406067; PMCID: PMC7815211. |